When This Medicine Should Not Be Used:
Do not use this medicine if you have had an allergic reaction to ursodiol or other bile acids. Do not use this medicine if you have biliary tract blockage, such as a blocked bile duct.

How to Use This Medicine:
Capsule, Tablet

• Your doctor will tell you how much medicine to use. Do not use more than directed.
• It is best to take this medicine with food or milk.
• Urso Forte® tablet can be broken in half, if needed. Place the tablet on a flat surface with the score (groove) on top. Hold the tablet with your thumbs close to the groove then apply gentle pressure until the tablet breaks apart. Swallow the half tablet with water. Do not chew.
• Gallstone treatment: Keep using the medicine for your full treatment time. It may take several months for the medicine to dissolve gallstones.

Drugs and Foods to Avoid:
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

• Make sure your doctor knows if you are also using an antacid that contains aluminum (ALternaGEL®, Gaviscon®, Maalox®, Mylanta®), medicine to lower cholesterol (such as cholestyramine, clofibrate, colestipol, Atromid-S®, Colestid®, Questran®), estrogen, or birth control pills.

Warnings While Using This Medicine:

• Make sure your doctor knows if you are pregnant or breastfeeding, or if you have other liver problems or pancreas problems.
• This medicine should not be used to treat bleeding varices, hepatic encephalopathy, or ascites.
• Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

Possible Side Effects While Using This Medicine:
Call your doctor right away if you notice any of these side effects:

• Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
• Chest pain
• Fever, chills, cough, sore throat, and body aches
• Severe nausea and vomiting
• Severe stomach pain especially on the right upper side
• Swelling in your hands, ankles, or feet
• Unusual bleeding or bruising

If you notice these less serious side effects, talk with your doctor:

• Diarrhea, constipation, loss of appetite, upset stomach, or gas
• Headache
• Indigestion or bitter taste in your mouth
• Itching, dry skin, rash, or hair thinning
• Weakness

If you notice other side effects that you think are caused by this medicine, tell your doctor.
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088