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Riluzole (Oral) (Tablet)

Riluzole (By mouth)
Riluzole (RIL-ue-zole)Treats amyotrophic lateral sclerosis (ALS).
Rilutek

When This Medicine Should Not Be Used:
This medicine is not right for everyone. Do not use it if you had an allergic reaction to riluzole.

How to Use This Medicine:
Tablet

  • Your doctor will tell you how much medicine to use. Do not use more than directed.
  • Take this medicine at least 1 hour before or 2 hours after meals.
  • Swallow the tablet whole. Do not crush, break, or chew it.
  • Missed dose: Skip the missed dose and take your next dose at the regular time. Do not use extra medicine to make up for a missed dose.
  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

Drugs and Foods to Avoid:
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Some medicines can affect how riluzole works. Tell your doctor if you are using any of the following:
    • Allopurinol, ciprofloxacin, enoxacin, fluvoxamine, methoxsalen, methyldopa, mexiletine, sulfasalazine, thiabendazole, vemurafenib, or zileuton
    • Birth control pills

Warnings While Using This Medicine:

  • Tell your doctor if you are pregnant or breastfeeding, or if you have liver disease. Tell your doctor if you have Japanese ancestry.
  • This medicine may cause the following problems:
    • Liver problems
    • Lung problems
  • This medicine lowers the number of white blood cells. This weakens your immune system, so you may get infections more easily. Wash your hands often. Avoid people who are sick.
  • Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Possible Side Effects While Using This Medicine:
Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Cough, trouble breathing
  • Dark urine or pale stools, nausea, vomiting, loss of appetite, stomach pain, yellow skin or eyes
  • Fever, chills, cough, sore throat, body aches

If you notice other side effects that you think are caused by this medicine, tell your doctor.
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088