When This Medicine Should Not Be Used:
This medicine is not right for everyone. You should not receive it if you had an allergic reaction to capreomycin.

How to Use This Medicine:
Injectable

• Your doctor will prescribe your exact dose and tell you how often it should be given. This medicine is given as a shot into one of your muscles.
• Take all of the medicine in your prescription to clear up your infection, even if you feel better after the first few doses.
• A nurse or other health provider will give you this medicine.
• You may be taught how to give your medicine at home. Make sure you understand all instructions before giving yourself an injection. Do not use more medicine or use it more often than your doctor tells you to.
• Missed dose: Call your doctor or pharmacist for instructions.
• This medicine should be mixed with sterile water or saline before use. Talk with your healthcare provider about the supplies you will need. After the medicine is mixed, it can be stored for up to 24 hours in the refrigerator.
• Check the medicine before each use. Do not use it if you see solid pieces or specks in the liquid.
• Throw away used needles in a hard, closed container that the needles cannot poke through. Keep this container away from children and pets.

Drugs and Foods to Avoid:
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

• Some medicines can affect how capreomycin works. Tell your doctor if you are also receiving amikacin, gentamicin, kanamycin, netilmicin, streptomycin, tobramycin, or vancomycin.

Warnings While Using This Medicine:

• Tell your doctor if you are pregnant or breastfeeding, or if you have hearing problems, kidney disease, liver disease, or any allergies, especially any allergic reactions to medicine.
• This medicine may cause the following problems:
  
  • Hearing loss
  • Kidney problems
• Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
• Tell any doctor or dentist who treats that you are using this medicine.
• Keep all medicine out of the reach of children. Never share your medicine with anyone.

Possible Side Effects While Using This Medicine:
Call your doctor right away if you notice any of these side effects:

• Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
• Decrease in how much or how often you urinate
• Dry mouth, increased thirst, muscle cramps, nausea or vomiting, uneven heartbeat
• Hearing loss, ringing in your ears, or dizziness
• Heavy bleeding or a lump where the shot is given
• Muscle spasms, stiffness, uneven heartbeat, lightheadedness, confusion
• Nausea, vomiting, unusual tiredness or weakness, muscle cramps, confusion
• Unusual bleeding or bruising

If you notice these less serious side effects, talk with your doctor:

• Pain where the shot is given

If you notice other side effects that you think are caused by this medicine, tell your doctor.
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088