TELLURIUM HEXAFLUORIDE

Little information is available on its effects in humans. This review is based on the known effects of TELLURIUM and FLUORIDE compounds in general, with specific effects attributed to TELLURIUM HEXAFLUORIDE indicated.
Based on animal studies, tellurium hexafluoride is considered seriously toxic by inhalation and may produce pulmonary edema and death. Animal studies suggest that tellurium hexafluorid is five times more toxic than selenium hexafluoride and 2.5 times more toxic than ozone (ACGIH, 1986). Effects in humans exposed to tellurium hexafluoride have included headache, dyspnea, garlic breath odor, and bluish-black discoloration of the skin (Proctor et al, 1988).
There have been no reports of workers dying or having serious symptoms from exposure to tellurium or its compounds (ACGIH, 1986). Tellurium is considered to be less toxic than selenium, but tellurites appear to be more toxic than selenites.
A garlicky odor of the breath and perspiration are effects seen with tellurium and its compounds, and are considered good indicators of systemic tellurium absorption (HSDB , 1995). These effects are thought to be due to the generation of dimethyl telluride. This odor is also found in urine, feces, and internal organs of sacrificed animals (Steinberg et al, 1942; Nyska et al, 1989). Ingestion of as little as 40 mcg of soluble tellurium may cause the unusual breath odor.
The ACGIH has established a Biological Exposure Index (BEI) for fluorides. See the BIOMONITORING section for more information.

FORMS

Tellurium hexafluoride is a colorless gas with a repulsive odor (Budavari, 1989).

SOURCES

It is a by-product of ore refining (Hathaway et al, 1991).

-CLINICAL EFFECTS

GENERAL CLINICAL EFFECTS

Tellurium hexafluoride is considered seriously toxic by inhalation and may produce pulmonary edema and death. Little information is available on its effects in humans, and no data for chronic exposure were found.

POTENTIAL HEALTH HAZARDS - EMERGENCY RESPONSE GUIDEBOOK, GUIDE 125 (ERG, 2004)

TOXIC; may be fatal if inhaled, ingested or absorbed through skin.
Vapors are extremely irritating and corrosive.
Contact with gas or liquefied gas may cause burns, severe injury and/or frostbite.
Fire will produce irritating, corrosive and/or toxic gases.
Runoff from fire control may cause pollution.

ACUTE CLINICAL EFFECTS

Tellurium hexafluoride is highly irritating to the eyes. One episode of acute inhalation of tellurium hexafluoride involving two persons produced metallic taste and a sour garlic odor on the breath (ACGIH, 1986).

Headache has been reported in humans acutely exposed to tellurium hexafluoride (Hathaway et al, 1991).

Tellurium hexafluoride is a respiratory tract irritant in experimental animals and is expected to cause similar effects in humans if exposure is severe (Proctor et al, 1988; HSDB , 1995). Disturbed breathing indicative of pulmonary edema occurred in four animal species exposed to 1 ppm tellurium hexafluoride for four hours (ACGIH, 1986). In one incident of acute human exposure to tellurium hexafluoride, no respiratory effects were reported (ACGIH, 1986). Dyspnea has been reported in exposed humans (Hathaway et al, 1991).

A dose of 1.5 grams of tellurium salts given subcutaneously to dogs produced respiratory depression and asphyxia within three days (Mead & Giese, 1901). Increased respirations were seen in rabbits, guinea pigs, rats, and mice exposed to 1 ppm tellurium hexafluoride for one hour (ACGIH, 1986). Repeated exposures to 1 ppm resulted in no effects, whereas exposure to 5 ppm for 4 hours was fatal to rodents (Hathaway et al, 1991).

Garlic breath odor, fatigue, bluish-black discoloration of the fingernails, and discolored streaks on the face and neck were noted in two human cases of exposure to 50 grams of tellurium hexafluoride which had leaked into a small laboratory room; complete recovery ensued without therapy (Hathaway et al, 1991). Giddiness and fatigue were reported in a 37-year-old female exposed to tellurium in a piece of meat she tasted containing 800 to 1000 mcg/kg of tellurium in the meat (Muller et al, 1989).

1.5 grams of tellurium salts injected subcutaneously into dogs in a four-hour period produced restlessness, paralysis, seizures, drowsiness, and coma within three days (Mead & Giese, 1901). Ingestion has resulted in "black brain" and black testes in rats (Finkel, 1983).

Anorexia has been a symptom reported after exposure to tellurium and its compounds (Muller et al, 1989). It was one of the symptoms noted in two cases of human exposure.

Nausea and vomiting may also develop in tellurium compound exposures, although they are not always present (Steinberg et al, 1942; Blackadder & Manderson, 1975; Muller et al, 1989).

A garlic odor of the breath and a metallic taste have been reported after exposure to tellurium and its compounds (Blackadder & Manderson, 1975; Muller et al, 1989). This odor may also be found in urine and feces (Steinberg et al, 1942; Muller et al, 1989).

The mucosa of the ureter and bladder was discolored in two fatal human cases of tellurium injection (Keal et al, 1946).

Reduced hemoglobin levels and hemolysis have been reported in animal studies (Steinberg et al, 1942). This was especially true with hydrogen telluride exposure (Finkel, 1983).

Reduction of sweating may result in scaly, dry skin and dermatitis (Finkel, 1983). Bluish-black patches were noted on the skin of the finger webs, neck, and face in a case report of two patients inadvertently exposed to 50 grams of tellurium hexafluoride (Blackadder & Manderson, 1975; ACGIH, 1986; Clayton & Clayton, 1981; Hathaway et al, 1991).

A 37-year-old patient with tellurium intoxication developed loss of hair and discoloration of new grown hair (Muller et al, 1989).

The investigational immunomodulator, AS-101 (a tellurium compound), has been shown to stimulate proliferation and interleukin-2 production in human lymphocytes in vitro, as well as production of interleukin-2 and colony stimulating factor in murine spleen cells (Sredni et al, 1987; Nyska et al, 1989).

CHRONIC CLINICAL EFFECTS

Dry mouth has been reported in tellurium workers exposed to fumes and dust for several weeks or months (Finkel, 1983).

Retinal changes have been observed in animals. Chronic experimental poisoning with metallic tellurium in cats has caused degenerative changes in the ganglion cells of the retina, an effect NOT reported in humans (Grant, 1986).

Kidney damage has been reported after repeated oral administration in experimental animals (Clayton & Clayton, 1981).

Proliferation of myelinated, non-dividing intraspinal Schwann cells was observed in rats fed 1.25% tellurium in the diet. This is thought to be due to initial tellurium-induced demyelination, which would provide a stimulus for Schwann cell division (Hammang et al, 1988).

Repeated exposures to 1 ppm resulted in no effects, whereas exposure to 5 ppm for 4 hours was fatal to rodents (Hathaway et al, 1991).

-MEDICAL TREATMENT

LIFE SUPPORT

Support respiratory and cardiovascular function.

SUMMARY

FIRST AID - EMERGENCY RESPONSE GUIDEBOOK, GUIDE 125 (ERG, 2004)

Move victim to fresh air.
Call 911 or emergency medical service.
Give artificial respiration if victim is not breathing.
Do not use mouth-to-mouth method if victim ingested or inhaled the substance; give artificial respiration with the aid of a pocket mask equipped with a one-way valve or other proper respiratory medical device.
Administer oxygen if breathing is difficult.
Remove and isolate contaminated clothing and shoes.
In case of contact with liquefied gas, thaw frosted parts with lukewarm water.
In case of contact with substance, immediately flush skin or eyes with running water for at least 20 minutes.
In case of contact with Hydrogen fluoride, anhydrous (UN1052), flush skin and eyes with water for 5 minutes; then, for skin exposures rub on a calcium/jelly combination; for eyes flush with a water/calcium solution for 15 minutes.
Keep victim warm and quiet.
Keep victim under observation.
Effects of contact or inhalation may be delayed.
Ensure that medical personnel are aware of the material(s) involved and take precautions to protect themselves.

-RANGE OF TOXICITY

MINIMUM LETHAL EXPOSURE

GENERAL/SUMMARY

The minimum lethal human dose to this agent has not been delineated.

MAXIMUM TOLERATED EXPOSURE

GENERAL/SUMMARY

Tellurites and tellurates in concentrations of 25 to 50 ppm placed in the diets of animals proved toxic. Elemental tellurium had only a slight effect on growth at 1500 ppm (ACGIH, 1991).
As little as 0.5 microgram produced the garlicky odor for 30 hours. An estimated dose of 15 milligrams produced an effect for 279 days (Blackadder & Manderson, 1975; Steinberg et al, 1942).

Carcinogenicity Ratings for CAS7783-80-4 :

ACGIH (American Conference of Governmental Industrial Hygienists, 2010): Not Listed ; Listed as: Tellurium hexafluoride, as Te
EPA (U.S. Environmental Protection Agency, 2011): Not Listed
IARC (International Agency for Research on Cancer (IARC), 2016; International Agency for Research on Cancer, 2015; IARC Working Group on the Evaluation of Carcinogenic Risks to Humans, 2010; IARC Working Group on the Evaluation of Carcinogenic Risks to Humans, 2010a; IARC Working Group on the Evaluation of Carcinogenic Risks to Humans, 2008; IARC Working Group on the Evaluation of Carcinogenic Risks to Humans, 2007; IARC Working Group on the Evaluation of Carcinogenic Risks to Humans, 2006; IARC, 2004): Not Listed
NIOSH (National Institute for Occupational Safety and Health, 2007): Not Listed ; Listed as: Tellurium hexafluoride
MAK (DFG, 2002): Not Listed
NTP (U.S. Department of Health and Human Services, Public Health Service, National Toxicology Project ): Not Listed

TOXICITY AND RISK ASSESSMENT VALUES

EPA IRIS

EPA Risk Assessment Values for CAS7783-80-4 (U.S. Environmental Protection Agency, 2011):

Not Listed

TOXICITY VALUES

Reference: RTECS, 1999
- LCLo- (INHALATION)GUINEA_PIG:
- LCLo- (INHALATION)MOUSE:
- LCLo- (INHALATION)RABBIT:
- LCLo- (INHALATION)RAT:

CALCULATIONS

AMBIENT CONVERSIONS

CONVERSION FACTORS

ppm = 0.101 x mg/m(3)

mg/m(3) = 9.88 x ppm

-STANDARDS AND LABELS

WORKPLACE STANDARDS

ACGIH TLV Values for CAS7783-80-4 (American Conference of Governmental Industrial Hygienists, 2010):

Editor's Note: The listed values are recommendations or guidelines developed by ACGIH(R) to assist in the control of health hazards. They should only be used, interpreted and applied by individuals trained in industrial hygiene. Before applying these values, it is imperative to read the introduction to each section in the current TLVs(R) and BEI(R) Book and become familiar with the constraints and limitations to their use. Always consult the Documentation of the TLVs(R) and BEIs(R) before applying these recommendations and guidelines.

Adopted Value

Tellurium hexafluoride, as Te

TLV:

TLV-TWA: 0.02 ppm
TLV-STEL:
TLV-Ceiling:

Notations and Endnotes:

Carcinogenicity Category: Not Listed
Codes: Not Listed
Definitions: Not Listed

TLV Basis - Critical Effect(s): LRT irr
Molecular Weight: 241.61

For gases and vapors, to convert the TLV from ppm to mg/m(3):

[(TLV in ppm)(gram molecular weight of substance)]/24.45

For gases and vapors, to convert the TLV from mg/m(3) to ppm:

[(TLV in mg/m(3))(24.45)]/gram molecular weight of substance

AIHA WEEL Values for CAS7783-80-4 (AIHA, 2006):

Not Listed

NIOSH REL and IDLH Values for CAS7783-80-4 (National Institute for Occupational Safety and Health, 2007):

Listed as: Tellurium hexafluoride
REL:

TWA: 0.02 ppm (0.2 mg/m(3))
STEL:
Ceiling:
Carcinogen Listing: (Not Listed) Not Listed
Skin Designation: Not Listed
Note(s):

IDLH:

IDLH: 1 ppm
Note(s): Not Listed

OSHA PEL Values for CAS7783-80-4 (U.S. Occupational Safety, and Health Administration (OSHA), 2010):

Listed as: Tellurium hexafluoride (as Te)
Table Z-1 for Tellurium hexafluoride (as Te):

8-hour TWA:

ppm: 0.02

Parts of vapor or gas per million parts of contaminated air by volume at 25 degrees C and 760 torr.

mg/m3: 0.2

Milligrams of substances per cubic meter of air. When entry is in this column only, the value is exact; when listed with a ppm entry, it is approximate.

Ceiling Value:
Skin Designation: No
Notation(s): Not Listed

OSHA List of Highly Hazardous Chemicals, Toxics, and Reactives for CAS7783-80-4 (U.S. Occupational Safety and Health Administration, 2010):

Threshold Quantity, in pounds:250

ENVIRONMENTAL STANDARDS

EPA CERCLA, Hazardous Substances and Reportable Quantities for CAS7783-80-4 (U.S. Environmental Protection Agency, 2010):

Not Listed

EPA CERCLA, Hazardous Substances and Reportable Quantities, Radionuclides for CAS7783-80-4 (U.S. Environmental Protection Agency, 2010):

Not Listed

EPA RCRA Hazardous Waste Number for CAS7783-80-4 (U.S. Environmental Protection Agency, 2010b):

Not Listed
Editor's Note: The D, F, and K series waste numbers and Appendix VIII to Part 261 -- Hazardous Constituents were not included. Please refer to 40 CFR Part 261.

EPA SARA Title III, Extremely Hazardous Substance List for CAS7783-80-4 (U.S. Environmental Protection Agency, 2010):

Listed as: Tellurium Hexafluoride
Reportable Quantity, in pounds: 100

Only the statutory or final RQ is shown. For more information, see 40 CFR table 302.4.

Threshold Planning Quantity, in pounds:

100
Amount necessary to be covered by this standard. See 40 CFR 355.30.

Note(s): e

e: The TPQ was revised due to calculation error, April 22, 1987.

EPA SARA Title III, Community Right-to-Know for CAS7783-80-4 (40 CFR 372.65, 2006; 40 CFR 372.28, 2006):

Not Listed

DOT List of Marine Pollutants for CAS7783-80-4 (49 CFR 172.101 - App. B, 2005):

Not Listed

EPA TSCA Inventory for CAS7783-80-4 (EPA, 2005):

Listed as: Tellurium fluoride (TeF6), (OC-6-11)-

SHIPPING REGULATIONS

SURFACE

DOT -- Table of Hazardous Materials and Special Provisions for UN/NA Number 2195 (49 CFR 172.101, 2005):

Hazardous materials descriptions and proper shipping name: Tellurium hexafluoride

Symbol(s): Not Listed
Hazard class or Division: 2.3

2.3: Poisonous gas. See 49 CFR section 173.115 for definitions.

Identification Number: UN2195
Packing Group: Not Listed
Label(s) required (if not excepted): 2.3, 8

2.3: Poison Gas.
8: Corrosive.

Special Provisions: 1

1: This material is poisonous by inhalation (see sxn. 171.8 of this subchapter) in Hazard Zone A (see sxn. 173.116(a) or sxn. 173.133(a) of this subchapter), and must be described as an inhalation hazard under the provisions of this subchapter.

Packaging Authorizations (refer to 49 CFR 173.***):

Exceptions: None
Non-bulk packaging: 302
Bulk packaging: None

Quantity Limitations:

Passenger aircraft or railcar: Forbidden
Cargo aircraft only: Forbidden

Vessel Stowage Requirements:

Vessel stowage location: D

D: The material must be stowed "on deck only" on a cargo vessel and on a passenger vessel carrying a number of passengers limited to not more than the larger of 25 passengers or one passenger per each 3 m of overall vessel length, but the material is prohibited on passenger vessels in which the limiting number of passengers is exceeded.

Vessel stowage other: 40

40: Stow "clear of living quarters".

ICAO International Shipping Name for UN2195 (ICAO, 2002):

Proper Shipping Name: Tellurium hexafluoride
UN Number: 2195

LABELS

NFPA

NFPA Hazard Ratings for CAS7783-80-4 (NFPA, 2002):

Not Listed

-PERSONAL PROTECTION

SUMMARY

RECOMMENDED PROTECTIVE CLOTHING - EMERGENCY RESPONSE GUIDEBOOK, GUIDE 125 (ERG, 2004)

Wear positive pressure self-contained breathing apparatus (SCBA).
Wear chemical protective clothing that is specifically recommended by the manufacturer. It may provide little or no thermal protection.
Structural firefighters' protective clothing provides limited protection in fire situations ONLY; it is not effective in spill situations where direct contact with the substance is possible.

PROTECTIVE CLOTHING

CHEMICAL PROTECTIVE CLOTHING. Search results for CAS 7783-80-4.

Specific recommendations and test data for this chemical were not found in the available manufacturers' product literature. A complete list of consulted manufacturers and references is presented below.

-PHYSICAL HAZARDS

FIRE HAZARD

SUMMARY

POTENTIAL FIRE OR EXPLOSION HAZARDS - EMERGENCY RESPONSE GUIDEBOOK, GUIDE 125 (ERG, 2004)
- Some may burn, but none ignite readily.
- Vapors from liquefied gas are initially heavier than air and spread along ground.
- Some of these materials may react violently with water.
- Cylinders exposed to fire may vent and release toxic and/or corrosive gas through pressure relief devices.
- Containers may explode when heated.
- Ruptured cylinders may rocket.

FLAMMABILITY CLASSIFICATION

NFPA Flammability Rating for CAS7783-80-4 (NFPA, 2002):

Not Listed

FIRE CONTROL/EXTINGUISHING AGENTS

SMALL FIRE PRECAUTIONS - EMERGENCY RESPONSE GUIDEBOOK, GUIDE 125 (ERG, 2004)

Dry chemical or CO2.

LARGE FIRE PRECAUTIONS - EMERGENCY RESPONSE GUIDEBOOK, GUIDE 125 (ERG, 2004)

Water spray, fog or regular foam.
Move containers from fire area if you can do it without risk.
Do not get water inside containers.
Damaged cylinders should be handled only by specialists.

TANK FIRE PRECAUTIONS - EMERGENCY RESPONSE GUIDEBOOK, GUIDE 125 (ERG, 2004)

Fight fire from maximum distance or use unmanned hose holders or monitor nozzles.
Cool containers with flooding quantities of water until well after fire is out.
Do not direct water at source of leak or safety devices; icing may occur.
Withdraw immediately in case of rising sound from venting safety devices or discoloration of tank.
ALWAYS stay away from tanks engulfed in fire.

NFPA Extinguishing Methods for CAS7783-80-4 (NFPA, 2002):

Not Listed

EVACUATION PROCEDURES

SUMMARY

Initial Isolation and Protective Action Distances (ERG, 2004)

Data presented from the Emergency Response Guidebook Table of Initial Isolation and Protective Action Distances are for use when a spill has occurred and there is no fire. If there is a fire, or if a fire is involved, evacuation information presented under FIRE - PUBLIC SAFETY EVACUATION DISTANCES should be used.
Generally, a small spill is one that involves a single, small package such as a drum containing up to approximately 200 liters, a small cylinder, or a small leak from a large package. A large spill is one that involves a spill from a large package, or multiple spills from many small packages.
Suggested distances to protect from vapors of toxic-by-inhalation and/or water-reactive materials during the first 30 minutes following the spill.

DOT ID No. 2195 - Tellurium hexafluoride

SMALL SPILLS

First isolate in all directions: 90 meters (300 feet).
Note wind direction.
Then protect persons downwind:

during the DAY for: 1 kilometers (0.6 miles); or
during the NIGHT for: 4 kilometers (2.5 miles).

LARGE SPILLS

First isolate in all directions: 600 meters (2000 feet).
Note wind direction.
Then protect persons downwind:

during the DAY for: 6 kilometers (3.7 miles); or
during the NIGHT for: 11.0+ kilometers (7.0+ miles).

SPILL - PUBLIC SAFETY EVACUATION DISTANCES - EMERGENCY RESPONSE GUIDEBOOK, GUIDE 125 (ERG, 2004)

Increase, in the downwind direction, as necessary, the isolation distance of at least 100 meters (330 feet) in all directions.

FIRE - PUBLIC SAFETY EVACUATION DISTANCES - EMERGENCY RESPONSE GUIDEBOOK, GUIDE 125 (ERG, 2004)

If tank, rail car or tank truck is involved in a fire, ISOLATE for 1600 meters (1 mile) in all directions; also, consider initial evacuation for 1600 meters (1 mile) in all directions.

PUBLIC SAFETY MEASURES - EMERGENCY RESPONSE GUIDEBOOK, GUIDE 125 (ERG, 2004)

CALL Emergency Response Telephone Number on Shipping Paper first. If Shipping Paper not available or no answer, refer to appropriate telephone number:

MEXICO:

SETIQ:

01-800-00-214-00 in the Mexican Republic;
For calls originating in Mexico City and the Metropolitan Area: 5559-1588;
For calls originating elsewhere, call: 011-52-555-559-1588.

CENACOM:

01-800-00-413-00 in the Mexican Republic;
For calls originating in Mexico City and the Metropolitan Area: 5550-1496, 5550-1552, 5550-1485, or 5550-4885;
For calls originating elsewhere, call: 011-52-555-550-1496, or 011-52-555-550-1552; 011-52-555-550-1485, or 011-52-555-550-4885.

ARGENTINA:

CIQUIME:

0-800-222-2933 in the Republic of Argentina;
For calls originating elsewhere, call: +54-11-4613-1100.

BRAZIL:

PRÓ-QUÍMICA:

0-800-118270 (Toll-free in Brazil);
For calls originating elsewhere, call: +55-11-232-1144 (Collect calls are accepted).

COLUMBIA:

CISPROQUIM:

01-800-091-6012 in Colombia;
For calls originating in Bogotá, Colombia, call: 288-6012;
For calls originating elsewhere, call: 011-57-1-288-6012.

CANADA:

CANUTEC:

613-996-6666 (Collect calls are accepted);
*666 cellular (in Canada only).

UNITED STATES:

CHEMTREC®:

1-800-424-9300 (Toll-free in the U.S., Canada, and the U.S. Virgin Islands);
703-527-3887 for calls originating elsewhere (Collect calls are accepted).

CHEM-TEL, INC.:

1-800-255-3924 (Toll-free in the U.S., Canada, and the U.S. Virgin Islands);
813-248-0585 for calls originating elsewhere (Collect calls are accepted).

INFOTRAC:

1-800-535-5053 (Toll-free in the U.S., Canada, and the U.S. Virgin Islands);
352-323-3500 for calls originating elsewhere (Collect calls are accepted).

3E COMPANY:

1-800-451-8346 (Toll-free in the U.S., Canada, and the U.S. Virgin Islands);
760-602-8703 for calls originating elsewhere (Collect calls are accepted).

NATIONAL RESPONSE CENTER (NRC):

1-800-424-8802 - (24 hours) (Toll-free in the U.S., Canada, and the U.S. Virgin Islands);
202-267-2675 for calls in the District of Columbia.

MILITARY SHIPMENTS:

703-697-0218 - Explosives/ammunition incidents (Collect calls are accepted);
1-800-851-8061 - All other dangerous goods incidents.

NATIONWIDE POISON CONTROL CENTER (United States only):

1-800-222-1222 (Toll-free in the U.S.).

For additional details see the section entitled "WHO TO CALL FOR ASSISTANCE" under the ERG Instructions.
As an immediate precautionary measure, isolate spill or leak area for at least 100 meters (330 feet) in all directions.
Keep unauthorized personnel away.
Stay upwind.
Many gases are heavier than air and will spread along ground and collect in low or confined areas (sewers, basements, tanks).
Keep out of low areas.
Ventilate closed spaces before entering.

AIHA ERPG Values for CAS7783-80-4 (AIHA, 2006):

Not Listed

DOE TEEL Values for CAS7783-80-4 (U.S. Department of Energy, Office of Emergency Management, 2010):

Listed as Tellurium hexafluoride
TEEL-0 (units = ppm): 0.018
TEEL-1 (units = ppm): 0.018
TEEL-2 (units = ppm): 0.018
TEEL-3 (units = ppm): 0.053
Definitions:

TEEL-0: The threshold concentration below which most people will experience no adverse health effects.
TEEL-1: The airborne concentration (expressed as ppm [parts per million] or mg/m(3) [milligrams per cubic meter]) of a substance above which it is predicted that the general population, including susceptible individuals, could experience notable discomfort, irritation, or certain asymptomatic, nonsensory effects. However, these effects are not disabling and are transient and reversible upon cessation of exposure.
TEEL-2: The airborne concentration (expressed as ppm or mg/m(3)) of a substance above which it is predicted that the general population, including susceptible individuals, could experience irreversible or other serious, long-lasting, adverse health effects or an impaired ability to escape.
TEEL-3: The airborne concentration (expressed as ppm or mg/m(3)) of a substance above which it is predicted that the general population, including susceptible individuals, could experience life-threatening adverse health effects or death.

AEGL Values for CAS7783-80-4 (National Research Council, 2010; National Research Council, 2009; National Research Council, 2008; National Research Council, 2007; NRC, 2001; NRC, 2002; NRC, 2003; NRC, 2004; NRC, 2004; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2006; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2007; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2005; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2005; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2007; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2006; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2006; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2006; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2006; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2006; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2006; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2006; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2006; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2006; United States Environmental Protection Agency Office of Pollution Prevention and Toxics, 2006; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2006; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2007; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2007; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2007; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2007; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2007; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2009; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2009; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2009; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2009; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2009; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2009; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2009; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2009; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2009; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2009; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2009; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2009; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2009; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2007; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2006; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2006; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2006; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2007; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2007; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2007; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2007; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2007; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2005; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2005; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2005; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2005; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2005; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2005; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2005; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2005; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2007; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2005; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2006; 62 FR 58840, 1997; 65 FR 14186, 2000; 65 FR 39264, 2000; 65 FR 77866, 2000; 66 FR 21940, 2001; 67 FR 7164, 2002; 68 FR 42710, 2003; 69 FR 54144, 2004):

Listed as: Tellurium hexafluoride
Proposed Value:

AEGL-1

10 min exposure:

ppm:
mg/m3: Not recommended because of insufficient data

30 min exposure:

ppm:
mg/m3: Not recommended because of insufficient data

1 hr exposure:

ppm:
mg/m3: Not recommended because of insufficient data

4 hr exposure:

ppm:
mg/m3: Not recommended because of insufficient data

8 hr exposure:

ppm:
mg/m3: Not recommended because of insufficient data

Definitions:

AEGL-1 is the airborne concentration of a substance above which it is predicted that the general population, including susceptible individuals, could experience notable discomfort, irritation, or certain asymptomatic non-sensory effects. However, the effects are not disabling, are transient, and are reversible upon cessation of exposure.

Listed as: Tellurium hexafluoride
Proposed Value:

AEGL-2

10 min exposure:

ppm: 0.032 ppm
mg/m3: 0.32 mg/m(3)

30 min exposure:

ppm: 0.022 ppm
mg/m3: 0.22 mg/m(3)

1 hr exposure:

ppm: 0.018 ppm
mg/m3: 0.18 mg/m(3)

4 hr exposure:

ppm: 0.011 ppm
mg/m3: 0.11 mg/m(3)

8 hr exposure:

ppm: 0.0057 ppm
mg/m3: 0.056 mg/m(3)

Definitions:

AEGL-2 is the airborne concentration of a substance above which it is predicted that the general population, including susceptible individuals, could experience irreversible or other serious, long-lasting adverse health effects or an impaired ability to escape.

Listed as: Tellurium hexafluoride
Proposed Value:

AEGL-3

10 min exposure:

ppm: 0.096 ppm
mg/m3: 0.95 mg/m(3)

30 min exposure:

ppm: 0.067 ppm
mg/m3: 0.66 mg/m(3)

1 hr exposure:

ppm: 0.053 ppm
mg/m3: 0.52 mg/m(3)

4 hr exposure:

ppm: 0.033 ppm
mg/m3: 0.33 mg/m(3)

8 hr exposure:

ppm: 0.017
mg/m3: 0.17 mg/m(3)

Definitions:

AEGL-3 is the airborne concentration of a substance above which it is predicted that the general population, including susceptible individuals, could experience life-threatening health effects or death.

NIOSH IDLH Values for CAS7783-80-4 (National Institute for Occupational Safety and Health, 2007):

IDLH: 1 ppm
Note(s): Not Listed

CONTAINMENT/WASTE TREATMENT OPTIONS

SUMMARY

SPILL OR LEAK PRECAUTIONS - EMERGENCY RESPONSE GUIDEBOOK, GUIDE 125 (ERG, 2004)
- Fully encapsulating, vapor protective clothing should be worn for spills and leaks with no fire.
- Do not touch or walk through spilled material.
- Stop leak if you can do it without risk.
- If possible, turn leaking containers so that gas escapes rather than liquid.
- Prevent entry into waterways, sewers, basements or confined areas.
- Do not direct water at spill or source of leak.
- Use water spray to reduce vapors or divert vapor cloud drift. Avoid allowing water runoff to conact spilled material.
- Isolate area until gas has dispersed.
RECOMMENDED PROTECTIVE CLOTHING - EMERGENCY RESPONSE GUIDEBOOK, GUIDE 125 (ERG, 2004)
- Wear positive pressure self-contained breathing apparatus (SCBA).
- Wear chemical protective clothing that is specifically recommended by the manufacturer. It may provide little or no thermal protection.
- Structural firefighters' protective clothing provides limited protection in fire situations ONLY; it is not effective in spill situations where direct contact with the substance is possible.

-PHYSICAL/CHEMICAL PROPERTIES

MOLECULAR WEIGHT

241.59 (Budavari, 1996)

DESCRIPTION/PHYSICAL STATE

Tellurium hexafluoride exists as a colorless gas at standard temperature and pressure. It is noncombustible and has a repulsive odor (ACGIH, 1991; Budavari, 1996).

VAPOR PRESSURE

>760 torr (at 20 degrees C) (ACGIH, 1991)

DENSITY

OTHER TEMPERATURE AND/OR PRESSURE

SOLID: 4.006 g/mL (at -191 degrees C) (Budavari, 1996; Lewis, 1996)
LIQUID: 2.499 g/mL (at -10 degrees C) (Budavari, 1996; Lewis, 1996)
LIQUID: 3.025 g/mL (at -24 degrees C) (ACGIH, 1991)

FREEZING/MELTING POINT

MELTING POINT

-37.6 degrees C (Budavari, 1996)
-37.8 degrees C (ACGIH, 1991)

BOILING POINT

-38.9 degrees C (sublimes) (ACGIH, 1991; Lewis, 1996)

SOLUBILITY

IN WATER

Tellurium hexafluoride is absorbed by water slowly and undergoes hydrolysis to form telluric acid (Budavari, 1996).

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National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances: Acute Exposure Guideline Levels (AEGLs) for Carbonyl Sulfide (Proposed). United States Environmental Protection Agency. Washington, DC. 2007e. Available from URL: http://www.regulations.gov/search/Regs/contentStreamer?objectId=090000648037ff26&disposition=attachment&contentType=pdf. As accessed 2010-08-12.

National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances: Acute Exposure Guideline Levels (AEGLs) for Chlorobenzene (Proposed). United States Environmental Protection Agency. Washington, DC. 2008c. Available from URL: http://www.regulations.gov/search/Regs/contentStreamer?objectId=09000064803a52bb&disposition=attachment&contentType=pdf. As accessed 2010-08-12.

National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances: Acute Exposure Guideline Levels (AEGLs) for Cyanogen (Proposed). United States Environmental Protection Agency. Washington, DC. 2008f. Available from URL: http://www.regulations.gov/search/Regs/contentStreamer?objectId=09000064809187fe&disposition=attachment&contentType=pdf. As accessed 2010-08-15.

National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances: Acute Exposure Guideline Levels (AEGLs) for Dimethyl Phosphite (Proposed). United States Environmental Protection Agency. Washington, DC. 2009. Available from URL: http://www.regulations.gov/search/Regs/contentStreamer?objectId=0900006480a7cbf3&disposition=attachment&contentType=pdf. As accessed 2010-08-12.

National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances: Acute Exposure Guideline Levels (AEGLs) for Diphenylchloroarsine (Proposed). United States Environmental Protection Agency. Washington, DC. 2007l. Available from URL: http://www.regulations.gov/search/Regs/contentStreamer?objectId=090000648020fd29&disposition=attachment&contentType=pdf. As accessed 2010-08-16.

National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances: Acute Exposure Guideline Levels (AEGLs) for Ethyl Isocyanate (Proposed). United States Environmental Protection Agency. Washington, DC. 2008h. Available from URL: http://www.regulations.gov/search/Regs/contentStreamer?objectId=090000648091884e&disposition=attachment&contentType=pdf. As accessed 2010-08-15.

National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances: Acute Exposure Guideline Levels (AEGLs) for Ethyl Phosphorodichloridate (Proposed). United States Environmental Protection Agency. Washington, DC. 2008i. Available from URL: http://www.regulations.gov/search/Regs/contentStreamer?objectId=0900006480920347&disposition=attachment&contentType=pdf. As accessed 2010-08-15.

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National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances: Acute Exposure Guideline Levels (AEGLs) for Germane (Proposed). United States Environmental Protection Agency. Washington, DC. 2008j. Available from URL: http://www.regulations.gov/search/Regs/contentStreamer?objectId=0900006480963906&disposition=attachment&contentType=pdf. As accessed 2010-08-15.

National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances: Acute Exposure Guideline Levels (AEGLs) for Hexafluoropropylene (Proposed). United States Environmental Protection Agency. Washington, DC. 2006. Available from URL: http://www.regulations.gov/search/Regs/contentStreamer?objectId=09000064801ea1f5&disposition=attachment&contentType=pdf. As accessed 2010-08-15.

National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances: Acute Exposure Guideline Levels (AEGLs) for Ketene (Proposed). United States Environmental Protection Agency. Washington, DC. 2007. Available from URL: http://www.regulations.gov/search/Regs/contentStreamer?objectId=090000648020ee7c&disposition=attachment&contentType=pdf. As accessed 2010-08-15.

National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances: Acute Exposure Guideline Levels (AEGLs) for Magnesium Aluminum Phosphide (Proposed). United States Environmental Protection Agency. Washington, DC. 2005h. Available from URL: http://www.regulations.gov/search/Regs/contentStreamer?objectId=090000648020c5ed&disposition=attachment&contentType=pdf. As accessed 2010-08-16.

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National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances: Acute Exposure Guideline Levels (AEGLs) for Mercury Vapor (Proposed). United States Environmental Protection Agency. Washington, DC. 2009b. Available from URL: http://www.regulations.gov/search/Regs/contentStreamer?objectId=0900006480a8a087&disposition=attachment&contentType=pdf. As accessed 2010-08-12.

National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances: Acute Exposure Guideline Levels (AEGLs) for Methyl Isothiocyanate (Proposed). United States Environmental Protection Agency. Washington, DC. 2008k. Available from URL: http://www.regulations.gov/search/Regs/contentStreamer?objectId=0900006480963a03&disposition=attachment&contentType=pdf. As accessed 2010-08-15.

National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances: Acute Exposure Guideline Levels (AEGLs) for Methyl Parathion (Proposed). United States Environmental Protection Agency. Washington, DC. 2008l. Available from URL: http://www.regulations.gov/search/Regs/contentStreamer?objectId=0900006480963a57&disposition=attachment&contentType=pdf. As accessed 2010-08-12.

National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances: Acute Exposure Guideline Levels (AEGLs) for Methyl tertiary-butyl ether (Proposed). United States Environmental Protection Agency. Washington, DC. 2007a. Available from URL: http://www.regulations.gov/search/Regs/contentStreamer?objectId=09000064802a4985&disposition=attachment&contentType=pdf. As accessed 2010-08-15.

National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances: Acute Exposure Guideline Levels (AEGLs) for Methylchlorosilane (Proposed). United States Environmental Protection Agency. Washington, DC. 2005. Available from URL: http://www.regulations.gov/search/Regs/contentStreamer?objectId=090000648020c5f4&disposition=attachment&contentType=pdf. As accessed 2010-08-15.

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National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances: Acute Exposure Guideline Levels (AEGLs) for Nitrogen Tetroxide (Proposed). United States Environmental Protection Agency. Washington, DC. 2008n. Available from URL: http://www.regulations.gov/search/Regs/contentStreamer?objectId=090000648091855b&disposition=attachment&contentType=pdf. As accessed 2010-08-12.

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National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances: Acute Exposure Guideline Levels (AEGLs) for Perchloryl Fluoride (Proposed). United States Environmental Protection Agency. Washington, DC. 2009c. Available from URL: http://www.regulations.gov/search/Regs/contentStreamer?objectId=0900006480a7e268&disposition=attachment&contentType=pdf. As accessed 2010-08-12.

National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances: Acute Exposure Guideline Levels (AEGLs) for Perfluoroisobutylene (Proposed). United States Environmental Protection Agency. Washington, DC. 2009d. Available from URL: http://www.regulations.gov/search/Regs/contentStreamer?objectId=0900006480a7e26a&disposition=attachment&contentType=pdf. As accessed 2010-08-15.

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