SODIUM PENTACHLOROPHENATE

Both the sodium salt and the phenol have been used in home and industry as herbicides, disinfectants, mildew retardants, and wood preservatives (Baselt, 1988). It has been used in cooling towers to control the growth of algae (HSDB , 1997).

FORMS

Sodium pentachlorophenate is the sodium salt of PENTACHLOROPHENOL. It is available as a white or tan powder or buff-colored flakes, pellets, or briquets (EPA, 1985; HSDB , 1997). It has a phenolic odor (EPA, 1985). Sodium pentachlorophenate is soluble in water (21 to 29 percent weight/volume) and in ethanol and acetone; it is insoluble in benzene and petroleum oils (HSDB , 1997).

SOURCES

It has been banned for most uses in the USA because of its carcinogenic activity (Baselt, 1988). The toxic effects of sodium pentachlorophenate are identical to those of PENTACHLOROPHENOL (Clayton & Clayton, 1981). The following review is based on the toxicologic properties of pentachlorophenol. Effects attributed specifically to sodium pentachlorophenate are indicated.
Pentachlorophenol can be absorbed in toxic amounts by all routes of exposure, but skin exposure is the most dangerous (ACGIH, 1986).

-CLINICAL EFFECTS

GENERAL CLINICAL EFFECTS

The toxic effects of sodium pentachlorophenate are identical to those of pentachlorophenol. Either or both can produce severe eye, skin, and respiratory irritation or burns, anorexia, dyspnea, anesthesia, tachycardia, hyperpyrexia, sweating and flushing of the skin, rapidly progressing coma and death.

Onset of rigor mortis is especially rapid. Cerebral edema, inflammation of the gastric mucosa, pulmonary congestion, cardiac dilatation, and degenerative changes in the liver and kidney have been apparent at autopsy.

POTENTIAL HEALTH HAZARDS - EMERGENCY RESPONSE GUIDEBOOK, GUIDE 154 (ERG, 2004)

TOXIC; inhalation, ingestion or skin contact with material may cause severe injury or death.
Contact with molten substance may cause severe burns to skin and eyes.
Avoid any skin contact.
Effects of contact or inhalation may be delayed.
Fire may produce irritating, corrosive and/or toxic gases.
Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution.

ACUTE CLINICAL EFFECTS

Sodium pentachlorophenate produced elevated body temperature in rabbits irrespective of the route of administration (McGavack et al, 1941). Headache has been reported following pentachlorophenol exposure during application (Rugman & Cosstick, 1990).

Pentachlorophenol is a strong eye irritant (Finkel, 1983). It may cause lacrimation (Grant, 1986), burns, permanent corneal injury, corneal opacity, corneal numbness, and mydriasis.

There are several cases of retrobulbar neuritis associated with the use of a mixture containing pentachlorophenol (Campbell, 1952; Jindal, 1968). No cause and effect relationship has been established.

Pentachlorophenol irritates the nose and throat (Clayton & Clayton, 1981). Intense thirst is characteristic of severe pentachlorophenol intoxication (Blair, 1961; Morgan, 1989).

Elevated blood pressure was seen in exposed dogs, rats, and guinea pigs (HSDB , 1997). Pentachlorophenol poisoning has produced tachycardia (Baselt & Cravey, 1989; Gray, 1985). Cardiac dilatation has been reported from exposure to sodium pentachlorophenate (EPA, 1985). Heart failure is often a cause of death, with vascular damage seen (ACGIH, 1986).

Irritation and bronchitis may be seen with exposure to dust or sprays (Clayton & Clayton, 1981; Proctor et al, 1988; HSDB , 1997). Tachypnea is a symptom of intoxication in both experimental animals and humans (Clayton & Clayton, 1981; Gray, 1985; Baselt & Cravey, 1989; Morgan, 1989). Dyspnea, a sense of constriction in the chest, and pulmonary congestion occur with more severe intoxication (EPA, 1985).

Dizziness and headache may be seen (Proctor et al, 1988). CNS depression may occur following acute sodium pentachlorophenate exposure (EPA, 1985). Asphyxial convulsions have been seen in fatally poisoned experimental animals and humans (Clayton & Clayton, 1981; Gray, 1985).

Sodium pentachlorophenate exposure has been reported to cause cerebral edema; fatalities have been noted (Clayton & Clayton, 1981; Gray, 1985; EPA, 1985). Rapidly progressive coma has been reported from exposure to sodium pentachlorophenate (EPA, 1985) and pentachlorophenol (Baselt & Cravey, 1989).

Severe pentachlorophenol poisoning has produced restlessness, excitement, delirium, and confusion (Baselt & Cravey, 1989; Morgan, 1989).

Ingestion of sodium pentachlorophenate may cause inflammation of the gastric mucosa. Anorexia, gastrointestinal distress, and suspected pentachlorophenol-induced pancreatitis have been reported (Bergner et al, 1965; Clayton & Clayton, 1981) Cooper & Maccauley, 1982; (EPA, 1985).

Liver toxicity has been reported from exposure to sodium pentachlorophenate (EPA, 1985; HSDB , 1997). Centrilobular hepatic necrosis has been seen in fatal human cases (Clayton & Clayton, 1981; Gray, 1985). Hepatomegaly was seen in poisoned infants (Robson et al, 1969).

Kidney toxicity has been reported from exposure to sodium pentachlorophenate (EPA, 1985). Renal tubular degeneration has been seen in fatal cases. Renal output is first increased, then decreased in poisoned experimental animals and humans (Clayton & Clayton, 1981; Gray, 1985).

Sodium pentachlorophenate acts by uncoupling oxidative phosphorylation, producing increased basal metabolism, and increasing body temperature (Finkel, 1983). Profuse sweating may lead to fluid and electrolyte losses. Metabolic acidosis may be seen in severe cases (Gray, 1985; Robson et al, 1969).

Aplastic anemia and erythrocyte aplasia have been reported (Roberts, 1983; Roberts, 1981; Rugman & Cosstick, 1990). Intravascular hemolysis was reported in one woman who had dermal and inhalation exposure (Hassan et al, 1985).

Pentachlorophenol is a strong skin irritant (Finkel, 1983; HSDB , 1997). Irritation generally occurs with concentrations greater than 10 percent. Concentrations of less than 0.1 percent are unlikely to cause symptoms (Clayton & Clayton, 1981). Fatal poisonings have been seen after dermal exposure to concentrated pentachlorophenol (Jones et al, 1986).

Muscle spasms and tremor indicate severe intoxication (Morgan, 1989). Fatally poisoned experimental animals developed a rapidly progressing motor weakness (Clayton & Clayton, 1981). Profound rigor mortis usually develops rapidly after death due to pentachlorophenol poisoning (Clayton & Clayton, 1981; Gray, 1985).

Hyperglycemia and glycosuria have been seen in poisoned experimental animals (Clayton & Clayton, 1981; HSDB , 1997).

CHRONIC CLINICAL EFFECTS

Pentachlorophenol may exhibit CUMULATIVE SYSTEMIC TOXICITY (NIOSH/OSHA). Net daily uptake from occupational exposure has been calculated to range from 35 mcg to approximately 24 mg. Non-occupational exposures from treated wood can also be significant, with systemic absorption of up to 37 mcg/day (Reigner et al, 1992).

Lymphocytes from persons exposed to pentachlorophenol from treated wood in log cabins had a variety of immunological changes, including immunosuppression, autoimmunity against smooth muscle, enhanced natural killer cell activity, activated T-cells, and abnormal regulation of B-cells (McConnachie & Zahalsky, 1991). The noted increased incidence of low-grade infections and inflammations in workers exposed to pentachlorophenol is suggestive of immunological compromise (Klemmer, 1980).

Long-term occupational exposure to pentachlorophenol did not have major immunological effects in a group of 32 workers. There was a slightly reduced response to phytohemagluttinin in the group with the highest-level exposures, and there was a weak response against hepatocyte membrane in persons exposed for over 10 years (Colosio et al, 1993).

No significant changes in nerve conduction velocity could be detected in 10 workers exposed to pentachlorophenol at airborne concentrations of 0.3 to 180 mcg/m(3) for 4 to 24 years when measured serially at 4-year intervals (Triebig et al, 1987).

Respiratory symptoms and spirometric abnormalities were not increased in a group of persons manufacturing sodium pentachlorophenate and a butyl ester of 2,4,5-T (Embree et al, 1984). Low-grade infections, skin and eye irritation, and respiratory tract irritation were the main effects of low-level occupational exposure (Klemmer, 1980). High-level exposures can produce more severe effects, including aplastic anemia (Roberts, 1981).

Reduced glomerular filtration and tubular function have been seen in workers during pentachlorophenol exposure (Finkel, 1983). Chronic occupational exposure may cause weight loss (Bergner et al, 1965).

Other effects of chronic exposure include bronchitis, liver damage (NIOSH/OSHA), peripheral nerve damage (Triebig, 1981), sweating, weight loss, fever, and gastrointestinal distress (Bergner et al, 1965).

A 28-year-old male developed headaches, exertional dyspnea, and easy bruising associated with chronic exposure to a pentachlorophenol solution (Rugman & Cosstick, 1990).

Persons chronically exposed to pentachlorophenol have developed chloracne (Sehgal & Ghorpade, 1983; Proctor et al, 1988; Baselt & Cravey, 1989). Contaminants such as dioxins and dibenzofurans are the likely etiologic agents (O'Malley et al, 1990).

Contact dermatitis commonly occurs with occupational pentachlorophenol exposure. Occasional cases of exfoliative dermatitis, angioedema of the hands, and diffuse urticaria have been seen in heavily exposed workers (Morgan, 1989). Dermatitis may be seen with exposure to a solution as dilute as 1 percent if contact is frequent or prolonged. Sodium pentachlorophenate and pentachlorophenol were weak eczema allergens in human skin testing (Klaschka, 1979). Eczematous dermatitis has been reported from occupational exposure (L'Epee et al, 1962).

Pemphigus vulgaris and chronic urticaria have been reported in patients exposed in a non-occupational setting (Lambert et al, 1985; Kentor, 1986). Skin hyperpigmentation was seen in approximately 50 percent of workers manufacturing sodium pentachlorophenate and a butyl ester of 2,4,5-T (Jirasek et al, 1974).

Myalgias may be present in persons exposed to pentachlorophenol (Ellenhorn, 1997).

-MEDICAL TREATMENT

LIFE SUPPORT

Support respiratory and cardiovascular function.

SUMMARY

FIRST AID - EMERGENCY RESPONSE GUIDEBOOK, GUIDE 154 (ERG, 2004)

Move victim to fresh air.
Call 911 or emergency medical service.
Give artificial respiration if victim is not breathing.
Do not use mouth-to-mouth method if victim ingested or inhaled the substance; give artificial respiration with the aid of a pocket mask equipped with a one-way valve or other proper respiratory medical device.
Administer oxygen if breathing is difficult.
Remove and isolate contaminated clothing and shoes.
In case of contact with substance, immediately flush skin or eyes with running water for at least 20 minutes.
For minor skin contact, avoid spreading material on unaffected skin.
Keep victim warm and quiet.
Effects of exposure (inhalation, ingestion or skin contact) to substance may be delayed.
Ensure that medical personnel are aware of the material(s) involved and take precautions to protect themselves.

-RANGE OF TOXICITY

MINIMUM LETHAL EXPOSURE

GENERAL/SUMMARY

The minimum lethal human dose to this agent has not been delineated.
Fatalities have occurred from improper handling of sodium pentachlorophenate and pentachlorophenol (Gordon, 1956).

MAXIMUM TOLERATED EXPOSURE

ROUTE OF EXPOSURE

SKIN IRRITATION -

Concentrations of 10 percent or greater produce irritation after brief exposure; a one percent solution will cause irritation upon repeated contact; a 0.1 percent solution will irritate from prolonged contact (HSDB , 1998).

RESPIRATORY IRRITATION -

Painful irritation will occur in the nose of an uninitiated persons at concentrations greater than 1 mg/m(3); 2.4 mg/m(3) can be tolerated by accustomed persons (HSDB , 1998).
Concentrations of as little as 0.3 milligrams/cubic meter irritated the mucous membranes of lungs, eyes, nose, and the throat (Clayton & Clayton, 1981).
Concentrations of 1 milligram/cubic meter caused pain in the nose and throat as well as sneezing and coughing (Proctor et al, 1988).

INGESTION -

Severe toxic effects have occurred in adults after ingestion of 2 grams of pentachlorophenol (Ellenhorn & Barceloux, 1988).

Carcinogenicity Ratings for CAS131-52-2 :

ACGIH (American Conference of Governmental Industrial Hygienists, 2010): Not Listed
EPA (U.S. Environmental Protection Agency, 2011): Not Listed
IARC (International Agency for Research on Cancer (IARC), 2016; International Agency for Research on Cancer, 2015; IARC Working Group on the Evaluation of Carcinogenic Risks to Humans, 2010; IARC Working Group on the Evaluation of Carcinogenic Risks to Humans, 2010a; IARC Working Group on the Evaluation of Carcinogenic Risks to Humans, 2008; IARC Working Group on the Evaluation of Carcinogenic Risks to Humans, 2007; IARC Working Group on the Evaluation of Carcinogenic Risks to Humans, 2006; IARC, 2004): Not Listed
NIOSH (National Institute for Occupational Safety and Health, 2007): Not Listed
MAK (DFG, 2002): Not Listed
NTP (U.S. Department of Health and Human Services, Public Health Service, National Toxicology Project ): Not Listed

TOXICITY AND RISK ASSESSMENT VALUES

EPA IRIS

EPA Risk Assessment Values for CAS131-52-2 (U.S. Environmental Protection Agency, 2011):

Not Listed

TOXICITY VALUES

References: RTECS, 1998
- LC50- (INHALATION)GUINEA_PIG:
- LC50- (INHALATION)MOUSE:
- LD50- (INTRAPERITONEAL)MOUSE:
- LD50- (ORAL)MOUSE:
- LD50- (SKIN)MOUSE:
- LD50- (ORAL)RABBIT:
- LD50- (INHALATION)RAT:
- LD50- (ORAL)RAT:
- LD50- (SUBCUTANEOUS)RAT:
- LDLo- (SUBCUTANEOUS)DOG:
- LDLo- (INTRATRACHEAL)GUINEA_PIG:
- LDLo- (ORAL)GUINEA_PIG:
- LDLo- (SKIN)GUINEA_PIG:
- LDLo- (INTRATRACHEAL)MOUSE:
- LDLo- (SUBCUTANEOUS)MOUSE:
- LDLo- (INTRAPERITONEAL)RABBIT:
- LDLo- (INTRAVENOUS)RABBIT:
- LDLo- (SKIN)RABBIT:
- LDLo- (SUBCUTANEOUS)RABBIT:
- LDLo- (INTRATRACHEAL)RAT:

-STANDARDS AND LABELS

WORKPLACE STANDARDS

ACGIH TLV Values for CAS131-52-2 (American Conference of Governmental Industrial Hygienists, 2010):

Not Listed

AIHA WEEL Values for CAS131-52-2 (AIHA, 2006):

Not Listed

NIOSH REL and IDLH Values for CAS131-52-2 (National Institute for Occupational Safety and Health, 2007):

Not Listed

OSHA PEL Values for CAS131-52-2 (U.S. Occupational Safety, and Health Administration (OSHA), 2010):

Not Listed

OSHA List of Highly Hazardous Chemicals, Toxics, and Reactives for CAS131-52-2 (U.S. Occupational Safety and Health Administration, 2010):

Not Listed

ENVIRONMENTAL STANDARDS

EPA CERCLA, Hazardous Substances and Reportable Quantities for CAS131-52-2 (U.S. Environmental Protection Agency, 2010):

Not Listed

EPA CERCLA, Hazardous Substances and Reportable Quantities, Radionuclides for CAS131-52-2 (U.S. Environmental Protection Agency, 2010):

Not Listed

EPA RCRA Hazardous Waste Number for CAS131-52-2 (U.S. Environmental Protection Agency, 2010b):

Not Listed
Editor's Note: The D, F, and K series waste numbers and Appendix VIII to Part 261 -- Hazardous Constituents were not included. Please refer to 40 CFR Part 261.

EPA SARA Title III, Extremely Hazardous Substance List for CAS131-52-2 (U.S. Environmental Protection Agency, 2010):

Not Listed

EPA SARA Title III, Community Right-to-Know for CAS131-52-2 (40 CFR 372.65, 2006; 40 CFR 372.28, 2006):

Listed as: Sodium pentachlorophenate
Effective Date for Reporting Under 40 CFR 372.30:
Lower Thresholds for Chemicals of Special Concern under 40 CFR 372.28:

DOT List of Marine Pollutants for CAS131-52-2 (49 CFR 172.101 - App. B, 2005):

Listed as Sodium pentachlorophenate
Severe Marine Pollutant: Yes

EPA TSCA Inventory for CAS131-52-2 (EPA, 2005):

Listed as: Phenol, pentachloro-, sodium salt

SHIPPING REGULATIONS

SURFACE

DOT -- Table of Hazardous Materials and Special Provisions for UN/NA Number 2567 (49 CFR 172.101, 2005):

Hazardous materials descriptions and proper shipping name: Sodium pentachlorophenate

Symbol(s): Not Listed
Hazard class or Division: 6.1

6.1: Poisonous materials. See 49 CFR section 173.132 for definitions.

Identification Number: UN2567
Packing Group: II

II: Packing Group II - indicates the degree of danger presented by the material is medium.

Label(s) required (if not excepted): 6.1

6.1: Poison Inhalation Hazard (inhalation hazard, Zone A or B) or Poison (other than inhalation hazard, Zone A or B; the packing group for a material is indicated in column 5 of the table.).

Special Provisions: IB8, IP2, IP4, T3, TP33

IB8: Authorized IBCs: Metal (11A, 11B, 11N, 21A, 21B, 21N, 31A, 31B and 31N); Rigid plastics (11H1, 11H2, 21H1, 21H2, 31H1 and 31H2); Composite (11HZ1, 11HZ2, 21HZ1, 21HZ2, 31HZ1 and 31HZ2); Fiberboard (11G); Wooden (11C, 11D and 11F); Flexible (13H1, 13H2, 13H3, 13H4, 13H5, 13L1, 13L2, 13L3, 13L4, 13M1 or 13M2).
IP2: When IBCs other than metal or rigid plastics IBCs are used, they must be offered for transportation in a closed freight container or a closed transport vehicle.
IP4: Flexible, fiberboard or wooden IBCs must be sift-proof and water-resistant or be fitted with a sift-proof and water-resistant liner.
T3: Minimum test pressure (bar): 2.65; Minimum shell thickness (in mm-reference steel) (See sxn.178.274(d)): sxn.178.274(d)(2); Pressure-relief requirements (See sxn.178.275(g)): Normal; Bottom opening requirements (See sxn.178.275(d)): sxn.178.275(d)(2).
TP33: The portable tank instruction assigned for this substance applies for granular and powdered solids and for solids which are filled and discharged at temperatures above their melting point which are cooled and transported as a solid mass. Solid substances transported or offered for transport above their melting point are authorized for transportation in portable tanks conforming to the provisions of portable tank instruction T4 for solid substances of packing group III or T7 for solid substances of packing group II, unless a tank with more stringent requirements for minimum shell thickness, maximum allowable working pressure, pressure-relief devices or bottom outlets are assigned in which case the more stringent tank instruction and special provisions shall apply. Filling limits must be in accordance with portable tank special provision TP3. Solids meeting the defnintion of an elevated temperature material must be transported in accordance with the applicable requirements of this subchapter.

Packaging Authorizations (refer to 49 CFR 173.***):

Exceptions: 153
Non-bulk packaging: 212
Bulk packaging: 242

Quantity Limitations:

Passenger aircraft or railcar: 25 kg
Cargo aircraft only: 100 kg

Vessel Stowage Requirements:

Vessel stowage location: A

A: The material may be stowed "on deck" or "under deck" on a cargo vessel and on a passenger vessel.

Vessel stowage other: Not Listed

ICAO International Shipping Name for UN2567 (ICAO, 2002):

Proper Shipping Name: Sodium pentachlorophenate
UN Number: 2567

LABELS

NFPA

NFPA Hazard Ratings for CAS131-52-2 (NFPA, 2002):

Not Listed

-PERSONAL PROTECTION

SUMMARY

RECOMMENDED PROTECTIVE CLOTHING - EMERGENCY RESPONSE GUIDEBOOK, GUIDE 154 (ERG, 2004)

Wear positive pressure self-contained breathing apparatus (SCBA).
Wear chemical protective clothing that is specifically recommended by the manufacturer. It may provide little or no thermal protection.
Structural firefighters' protective clothing provides limited protection in fire situations ONLY; it is not effective in spill situations where direct contact with the substance is possible.

PROTECTIVE CLOTHING

CHEMICAL PROTECTIVE CLOTHING. Search results for CAS 131-52-2.

Specific recommendations and test data for this chemical were not found in the available manufacturers' product literature. A complete list of consulted manufacturers and references is presented below.

-PHYSICAL HAZARDS

FIRE HAZARD

SUMMARY

POTENTIAL FIRE OR EXPLOSION HAZARDS - EMERGENCY RESPONSE GUIDEBOOK, GUIDE 154 (ERG, 2004)
- Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes.
- Some are oxidizers and may ignite combustibles (wood, paper, oil, clothing, etc.).
- Contact with metals may evolve flammable hydrogen gas.
- Containers may explode when heated.

FLAMMABILITY CLASSIFICATION

NFPA Flammability Rating for CAS131-52-2 (NFPA, 2002):

Not Listed

FIRE CONTROL/EXTINGUISHING AGENTS

SMALL FIRE PRECAUTIONS - EMERGENCY RESPONSE GUIDEBOOK, GUIDE 154 (ERG, 2004)

Dry chemical, CO2 or water spray.

LARGE FIRE PRECAUTIONS - EMERGENCY RESPONSE GUIDEBOOK, GUIDE 154 (ERG, 2004)

Dry chemical, CO2, alcohol-resistant foam or water spray.
Move containers from fire area if you can do it without risk.
Dike fire control water for later disposal; do not scatter the material.

TANK OR CAR/TRAILER LOAD FIRE PRECAUTIONS - EMERGENCY RESPONSE GUIDEBOOK, GUIDE 154 (ERG, 2004)

Fight fire from maximum distance or use unmanned hose holders or monitor nozzles.
Do not get water inside containers.
Cool containers with flooding quantities of water until well after fire is out.
Withdraw immediately in case of rising sound from venting safety devices or discoloration of tank.
ALWAYS stay away from tanks engulfed in fire.

NFPA Extinguishing Methods for CAS131-52-2 (NFPA, 2002):

Not Listed

EVACUATION PROCEDURES

SUMMARY

Editor's Note: This material is not listed in the Table of Initial Isolation and Protective Action Distances.

SPILL - PUBLIC SAFETY EVACUATION DISTANCES - EMERGENCY RESPONSE GUIDEBOOK, GUIDE 154 (ERG, 2004)

Increase, in the downwind direction, as necessary, the isolation distance of at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids in all directions.

FIRE - PUBLIC SAFETY EVACUATION DISTANCES - EMERGENCY RESPONSE GUIDEBOOK, GUIDE 154 (ERG, 2004)

If tank, rail car or tank truck is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions.

PUBLIC SAFETY MEASURES - EMERGENCY RESPONSE GUIDEBOOK, GUIDE 154 (ERG, 2004)

CALL Emergency Response Telephone Number on Shipping Paper first. If Shipping Paper not available or no answer, refer to appropriate telephone number:

MEXICO:

SETIQ:

01-800-00-214-00 in the Mexican Republic;
For calls originating in Mexico City and the Metropolitan Area: 5559-1588;
For calls originating elsewhere, call: 011-52-555-559-1588.

CENACOM:

01-800-00-413-00 in the Mexican Republic;
For calls originating in Mexico City and the Metropolitan Area: 5550-1496, 5550-1552, 5550-1485, or 5550-4885;
For calls originating elsewhere, call: 011-52-555-550-1496, or 011-52-555-550-1552; 011-52-555-550-1485, or 011-52-555-550-4885.

ARGENTINA:

CIQUIME:

0-800-222-2933 in the Republic of Argentina;
For calls originating elsewhere, call: +54-11-4613-1100.

BRAZIL:

PRÓ-QUÍMICA:

0-800-118270 (Toll-free in Brazil);
For calls originating elsewhere, call: +55-11-232-1144 (Collect calls are accepted).

COLUMBIA:

CISPROQUIM:

01-800-091-6012 in Colombia;
For calls originating in Bogotá, Colombia, call: 288-6012;
For calls originating elsewhere, call: 011-57-1-288-6012.

CANADA:

CANUTEC:

613-996-6666 (Collect calls are accepted);
*666 cellular (in Canada only).

UNITED STATES:

CHEMTREC®:

1-800-424-9300 (Toll-free in the U.S., Canada, and the U.S. Virgin Islands);
703-527-3887 for calls originating elsewhere (Collect calls are accepted).

CHEM-TEL, INC.:

1-800-255-3924 (Toll-free in the U.S., Canada, and the U.S. Virgin Islands);
813-248-0585 for calls originating elsewhere (Collect calls are accepted).

INFOTRAC:

1-800-535-5053 (Toll-free in the U.S., Canada, and the U.S. Virgin Islands);
352-323-3500 for calls originating elsewhere (Collect calls are accepted).

3E COMPANY:

1-800-451-8346 (Toll-free in the U.S., Canada, and the U.S. Virgin Islands);
760-602-8703 for calls originating elsewhere (Collect calls are accepted).

NATIONAL RESPONSE CENTER (NRC):

1-800-424-8802 - (24 hours) (Toll-free in the U.S., Canada, and the U.S. Virgin Islands);
202-267-2675 for calls in the District of Columbia.

MILITARY SHIPMENTS:

703-697-0218 - Explosives/ammunition incidents (Collect calls are accepted);
1-800-851-8061 - All other dangerous goods incidents.

NATIONWIDE POISON CONTROL CENTER (United States only):

1-800-222-1222 (Toll-free in the U.S.).

For additional details see the section entitled "WHO TO CALL FOR ASSISTANCE" under the ERG Instructions.
As an immediate precautionary measure, isolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids.
Keep unauthorized personnel away.
Stay upwind.
Keep out of low areas.
Ventilate enclosed areas.

AIHA ERPG Values for CAS131-52-2 (AIHA, 2006):

Not Listed

DOE TEEL Values for CAS131-52-2 (U.S. Department of Energy, Office of Emergency Management, 2010):

Listed as Sodium pentachlorophenate
TEEL-0 (units = mg/m3): 1
TEEL-1 (units = mg/m3): 3.5
TEEL-2 (units = mg/m3): 24
TEEL-3 (units = mg/m3): 75
Definitions:

TEEL-0: The threshold concentration below which most people will experience no adverse health effects.
TEEL-1: The airborne concentration (expressed as ppm [parts per million] or mg/m(3) [milligrams per cubic meter]) of a substance above which it is predicted that the general population, including susceptible individuals, could experience notable discomfort, irritation, or certain asymptomatic, nonsensory effects. However, these effects are not disabling and are transient and reversible upon cessation of exposure.
TEEL-2: The airborne concentration (expressed as ppm or mg/m(3)) of a substance above which it is predicted that the general population, including susceptible individuals, could experience irreversible or other serious, long-lasting, adverse health effects or an impaired ability to escape.
TEEL-3: The airborne concentration (expressed as ppm or mg/m(3)) of a substance above which it is predicted that the general population, including susceptible individuals, could experience life-threatening adverse health effects or death.

AEGL Values for CAS131-52-2 (National Research Council, 2010; National Research Council, 2009; National Research Council, 2008; National Research Council, 2007; NRC, 2001; NRC, 2002; NRC, 2003; NRC, 2004; NRC, 2004; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2006; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2007; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2005; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2005; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2007; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2006; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2006; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2006; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2006; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2006; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2006; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2006; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2006; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2006; United States Environmental Protection Agency Office of Pollution Prevention and Toxics, 2006; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2006; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2007; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2007; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2007; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2007; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2007; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2009; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2009; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2009; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2009; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2009; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2009; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2009; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2009; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2009; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2009; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2009; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2009; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2009; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2007; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2006; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2006; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2006; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2007; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2007; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2007; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2007; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2007; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2005; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2005; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2005; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2005; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2005; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2005; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2005; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2005; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2007; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2005; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2006; 62 FR 58840, 1997; 65 FR 14186, 2000; 65 FR 39264, 2000; 65 FR 77866, 2000; 66 FR 21940, 2001; 67 FR 7164, 2002; 68 FR 42710, 2003; 69 FR 54144, 2004):

Not Listed

NIOSH IDLH Values for CAS131-52-2 (National Institute for Occupational Safety and Health, 2007):

Not Listed

CONTAINMENT/WASTE TREATMENT OPTIONS

SUMMARY

SPILL OR LEAK PRECAUTIONS - EMERGENCY RESPONSE GUIDEBOOK, GUIDE 154 (ERG, 2004)
- ELIMINATE all ignition sources (no smoking, flares, sparks or flames in immediate area).
- Do not touch damaged containers or spilled material unless wearing appropriate protective clothing.
- Stop leak if you can do it without risk.
- Prevent entry into waterways, sewers, basements or confined areas.
- Absorb or cover with dry earth, sand or other non-combustible material and transfer to containers.
- DO NOT GET WATER INSIDE CONTAINERS.
RECOMMENDED PROTECTIVE CLOTHING - EMERGENCY RESPONSE GUIDEBOOK, GUIDE 154 (ERG, 2004)
- Wear positive pressure self-contained breathing apparatus (SCBA).
- Wear chemical protective clothing that is specifically recommended by the manufacturer. It may provide little or no thermal protection.
- Structural firefighters' protective clothing provides limited protection in fire situations ONLY; it is not effective in spill situations where direct contact with the substance is possible.

-PHYSICAL/CHEMICAL PROPERTIES

MOLECULAR WEIGHT

288.32

-REFERENCES

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Classification | Information to evaluate chemical incidents

Information to evaluate chemical incidents

Information to evaluate chemical incidents

Information to evaluate chemical incidents