PHOSPHORUS OXYCHLORIDE

Phosphorus oxychloride is used as a chlorinating agent, often to replace oxygen in organic compounds. It also is used as a catalyzing agent and in the manufacture of fire retardants, cyclic and acyclic esters for plasticizers, gasoline additives, hydraulic fluids, organic phosphorus products, perfumes, nonflammable films, and pharmaceuticals (ACGIH, 1996a; Budavari, 1996; ITI, 1988; Lewis, 1997).
It also is used as a cryoscopy solvent, starch crosslinking agent, and dopant for semiconductor grade silicon (Ashford, 1994; Budavari, 1996; Lewis, 1997).

SOURCES

Phosphorus oxychloride is derived from phosphorus trichloride, phosphorus pentoxide, and chlorine (Lewis, 1997).
It can be made by heating phosphorus pentachloride with boric acid or iodide (HSDB , 2001).
It is produced by oxidating phosphorus trichloride (Ashford, 1994).

-CLINICAL EFFECTS

GENERAL CLINICAL EFFECTS

All reported cases involve inhalation by workers rather than ingestion.

Signs following exposure to vapors are irritation of the conjunctiva and mucous membranes, cough with sputum production, dyspnea, retrosternal chest pain, wheezing, dizziness, headache, weakness, anorexia, vomiting, bronchitis, pulmonary edema, nephritis, and a sense of suffocation. Exposure to vapors may cause skin burns.

Transient elevations of liver function tests and mild, transient albuminuria with minimal microscopic hematuria may follow significant inhalation exposure.

A chronic asthmatic-like bronchitis may develop after acute inhalation intoxication.

POTENTIAL HEALTH HAZARDS - EMERGENCY RESPONSE GUIDEBOOK, GUIDE 137 (ERG, 2004)

CORROSIVE and/or TOXIC; inhalation, ingestion or contact (skin, eyes) with vapors, dusts or substance may cause severe injury, burns, or death.
Fire will produce irritating, corrosive and/or toxic gases.
Reaction with water may generate much heat which will increase the concentration of fumes in the air.
Contact with molten substance may cause severe burns to skin and eyes.
Runoff from fire control or dilution water may cause pollution.

-FIRST AID

FIRST AID AND PREHOSPITAL TREATMENT

DILUTION-

DILUTION: If no respiratory compromise is present, administer milk or water as soon as possible after ingestion. Dilution may only be helpful if performed in the first seconds to minutes after ingestion. The ideal amount is unknown; no more than 8 ounces (240 mL) in adults and 4 ounces (120 mL) in children is recommended to minimize the risk of vomiting (Caravati, 2004).

EMESIS/NOT RECOMMENDED-

EMESIS SHOULD BE AVOIDED due to potential severe irritation and release of acids (CHRIS, 1985).

ACTIVATED CHARCOAL/NOT RECOMMENDED-

Activated charcoal is of no value and may obscure endoscopy findings; it should be avoided.

-MEDICAL TREATMENT

LIFE SUPPORT

Support respiratory and cardiovascular function.

SUMMARY

FIRST AID - EMERGENCY RESPONSE GUIDEBOOK, GUIDE 137 (ERG, 2004)

Move victim to fresh air.
Call 911 or emergency medical service.
Give artificial respiration if victim is not breathing.
Do not use mouth-to-mouth method if victim ingested or inhaled the substance; give artificial respiration with the aid of a pocket mask equipped with a one-way valve or other proper respiratory medical device.
Administer oxygen if breathing is difficult.
Remove and isolate contaminated clothing and shoes.
In case of contact with substance, immediately flush skin or eyes with running water for at least 20 minutes.
For minor skin contact, avoid spreading material on unaffected skin.
Removal of solidified molten material from skin requires medical assistance.
Keep victim warm and quiet.
Effects of exposure (inhalation, ingestion or skin contact) to substance may be delayed.
Ensure that medical personnel are aware of the material(s) involved and take precautions to protect themselves.

FIRST AID

FIRST AID

EYE EXPOSURE - Immediately wash the eyes with large amounts of water, occasionally lifting the lower and upper lids. Get medical attention immediately. Contact lenses should not be worn when working with this chemical.
DERMAL EXPOSURE - Immediately flush the contaminated skin with water. If this chemical penetrates the clothing, immediately remove the clothing and flush the skin with water. Get medical attention promptly.
INHALATION EXPOSURE - Move the exposed person to fresh air at once. If breathing has stopped, perform artificial respiration. Keep the affected person warm and at rest. Get medical attention as soon as possible.
ORAL EXPOSURE - If this chemical has been swallowed, get medical attention immediately.
TARGET ORGANS - Eyes, skin, respiratory system, central nervous system, and kidneys (National Institute for Occupational Safety and Health, 2007).

GENERAL -

Move victims of inhalation exposure from the toxic environment and administer 100% humidified supplemental oxygen with assisted ventilation as required. Exposed skin and eyes should be copiously flushed with water. Because of the potential for rapid onset of CNS depression or seizures with possible aspiration of gastric contents, EMESIS SHOULD NOT BE INDUCED. Cautious gastric lavage followed by administration of activated charcoal may be of benefit if the patient is seen soon after the exposure.

INHALATION EXPOSURE -

INHALATION: Move patient to fresh air. Monitor for respiratory distress. If cough or difficulty breathing develops, evaluate for respiratory tract irritation, bronchitis, or pneumonitis. Administer oxygen and assist ventilation as required. Treat bronchospasm with an inhaled beta2-adrenergic agonist. Consider systemic corticosteroids in patients with significant bronchospasm.
If bronchospasm and wheezing occur, consider treatment with inhaled sympathomimetic agents.
ACUTE LUNG INJURY: Maintain ventilation and oxygenation and evaluate with frequent arterial blood gases and/or pulse oximetry monitoring. Early use of PEEP and mechanical ventilation may be needed.

DERMAL EXPOSURE -

DECONTAMINATION: Remove contaminated clothing and jewelry and place them in plastic bags. Wash exposed areas with soap and water for 10 to 15 minutes with gentle sponging to avoid skin breakdown. A physician may need to examine the area if irritation or pain persists (Burgess et al, 1999).
Treat dermal irritation or burns with standard topical therapy. Patients developing dermal hypersensitivity reactions may require treatment with systemic or topical corticosteroids or antihistamines.

EYE EXPOSURE -

DECONTAMINATION: Remove contact lenses and irrigate exposed eyes with copious amounts of room temperature 0.9% saline or water for at least 15 minutes. If irritation, pain, swelling, lacrimation, or photophobia persist after 15 minutes of irrigation, the patient should be seen in a healthcare facility.

ORAL EXPOSURE -

Because of the potential for CNS depression or gastrointestinal tract irritation, DO NOT induce emesis.
Significant esophageal or gastrointestinal tract irritation or burns may occur following ingestion. The possible benefit of early removal of some ingested material by cautious gastric lavage must be weighed against potential complications of bleeding or perforation.
GASTRIC LAVAGE: Consider after ingestion of a potentially life-threatening amount of poison if it can be performed soon after ingestion (generally within 1 hour). Protect airway by placement in the head down left lateral decubitus position or by endotracheal intubation. Control any seizures first.

CONTRAINDICATIONS: Loss of airway protective reflexes or decreased level of consciousness in unintubated patients; following ingestion of corrosives; hydrocarbons (high aspiration potential); patients at risk of hemorrhage or gastrointestinal perforation; and trivial or non-toxic ingestion.

ACTIVATED CHARCOAL: Administer charcoal as a slurry (240 mL water/30 g charcoal). Usual dose: 25 to 100 g in adults/adolescents, 25 to 50 g in children (1 to 12 years), and 1 g/kg in infants less than 1 year old.
Observe patients with ingestion carefully for the possible development of esophageal or gastrointestinal tract irritation or burns. If signs or symptoms of esophageal irritation or burns are present, consider endoscopy to determine the extent of injury.

-RANGE OF TOXICITY

MINIMUM LETHAL EXPOSURE

GENERAL/SUMMARY

The minimum lethal human exposure to phosphorus oxychloride has not been established. Deaths from acute exposure have not been reported, although one reference mentions two late deaths from chronic pulmonary sequelae (Scotti, 1967).

MAXIMUM TOLERATED EXPOSURE

GENERAL/SUMMARY

Although specific values have not been reported in the standard references, chronic and acute occupational exposure cases have been reported. Symptoms following exposure to phosphorus oxychloride vapor include severe eye, skin, and mucous membrane irritation, weakness, dizziness, headache, anorexia, nausea, vomiting, cough, dyspnea, chest pain, bronchitis, bronchopneumonia, pulmonary edema, and nephritis (ACGIH, 1996a).

Carcinogenicity Ratings for CAS10025-87-3 :

ACGIH (American Conference of Governmental Industrial Hygienists, 2010): Not Listed ; Listed as: Phosphorus oxychloride
EPA (U.S. Environmental Protection Agency, 2011): Not Listed
IARC (International Agency for Research on Cancer (IARC), 2016; International Agency for Research on Cancer, 2015; IARC Working Group on the Evaluation of Carcinogenic Risks to Humans, 2010; IARC Working Group on the Evaluation of Carcinogenic Risks to Humans, 2010a; IARC Working Group on the Evaluation of Carcinogenic Risks to Humans, 2008; IARC Working Group on the Evaluation of Carcinogenic Risks to Humans, 2007; IARC Working Group on the Evaluation of Carcinogenic Risks to Humans, 2006; IARC, 2004): Not Listed
NIOSH (National Institute for Occupational Safety and Health, 2007): Not Listed ; Listed as: Phosphorus oxychloride
MAK (DFG, 2002): Not Listed
NTP (U.S. Department of Health and Human Services, Public Health Service, National Toxicology Project ): Not Listed

TOXICITY AND RISK ASSESSMENT VALUES

EPA IRIS

EPA Risk Assessment Values for CAS10025-87-3 (U.S. Environmental Protection Agency, 2011):

Not Listed

TOXICITY VALUES

ANIMAL DATA
- LC50- (INHALATION)GUINEA_PIG:
- LC50- (INHALATION)MOUSE:
- LC50- (INHALATION)RAT:
- LD50- (ORAL)MOUSE:
- LD50- (ORAL)RAT:

-STANDARDS AND LABELS

WORKPLACE STANDARDS

ACGIH TLV Values for CAS10025-87-3 (American Conference of Governmental Industrial Hygienists, 2010):

Editor's Note: The listed values are recommendations or guidelines developed by ACGIH(R) to assist in the control of health hazards. They should only be used, interpreted and applied by individuals trained in industrial hygiene. Before applying these values, it is imperative to read the introduction to each section in the current TLVs(R) and BEI(R) Book and become familiar with the constraints and limitations to their use. Always consult the Documentation of the TLVs(R) and BEIs(R) before applying these recommendations and guidelines.

Adopted Value

Phosphorus oxychloride

TLV:

TLV-TWA: 0.1 ppm
TLV-STEL:
TLV-Ceiling:

Notations and Endnotes:

Carcinogenicity Category: Not Listed
Codes: Not Listed
Definitions: Not Listed

TLV Basis - Critical Effect(s): URT irr
Molecular Weight: 153.35

For gases and vapors, to convert the TLV from ppm to mg/m(3):

[(TLV in ppm)(gram molecular weight of substance)]/24.45

For gases and vapors, to convert the TLV from mg/m(3) to ppm:

[(TLV in mg/m(3))(24.45)]/gram molecular weight of substance

AIHA WEEL Values for CAS10025-87-3 (AIHA, 2006):

Not Listed

NIOSH REL and IDLH Values for CAS10025-87-3 (National Institute for Occupational Safety and Health, 2007):

Listed as: Phosphorus oxychloride
REL:

TWA: 0.1 ppm (0.6 mg/m(3))
STEL: 0.5 ppm (3 mg/m(3))
Ceiling:
Carcinogen Listing: (Not Listed) Not Listed
Skin Designation: Not Listed
Note(s):

IDLH: Not Listed

OSHA PEL Values for CAS10025-87-3 (U.S. Occupational Safety, and Health Administration (OSHA), 2010):

Not Listed

OSHA List of Highly Hazardous Chemicals, Toxics, and Reactives for CAS10025-87-3 (U.S. Occupational Safety and Health Administration, 2010):

Threshold Quantity, in pounds:1000
Threshold Quantity, in pounds:1000

ENVIRONMENTAL STANDARDS

EPA CERCLA, Hazardous Substances and Reportable Quantities for CAS10025-87-3 (U.S. Environmental Protection Agency, 2010):

Listed as: Phosphorus oxychloride
Final Reportable Quantity, in pounds (kilograms):

1000 (454)

Additional Information:

EPA CERCLA, Hazardous Substances and Reportable Quantities, Radionuclides for CAS10025-87-3 (U.S. Environmental Protection Agency, 2010):

Not Listed

EPA RCRA Hazardous Waste Number for CAS10025-87-3 (U.S. Environmental Protection Agency, 2010b):

Not Listed
Editor's Note: The D, F, and K series waste numbers and Appendix VIII to Part 261 -- Hazardous Constituents were not included. Please refer to 40 CFR Part 261.

EPA SARA Title III, Extremely Hazardous Substance List for CAS10025-87-3 (U.S. Environmental Protection Agency, 2010):

Listed as: Phosphorus Oxychloride
Reportable Quantity, in pounds: 1000

Only the statutory or final RQ is shown. For more information, see 40 CFR table 302.4.

Threshold Planning Quantity, in pounds:

500
Amount necessary to be covered by this standard. See 40 CFR 355.30.

Note(s): Not Listed

EPA SARA Title III, Community Right-to-Know for CAS10025-87-3 (40 CFR 372.65, 2006; 40 CFR 372.28, 2006):

Not Listed

DOT List of Marine Pollutants for CAS10025-87-3 (49 CFR 172.101 - App. B, 2005):

Not Listed

EPA TSCA Inventory for CAS10025-87-3 (EPA, 2005):

Listed as: Phosphoric trichloride

SHIPPING REGULATIONS

SURFACE

DOT -- Table of Hazardous Materials and Special Provisions for UN/NA Number 1810 (49 CFR 172.101, 2005):

Hazardous materials descriptions and proper shipping name: Phosphorus oxychloride

Symbol(s): +

+: fixes the proper shipping name, hazard class and packing group for that entry without regard to whether the material meets the definition of that class, packing group or any other hazard class definition. When the plus sign is assigned to a proper shipping name, it means that the material is known to pose a risk to humans. When a plus sign is assigned to mixtures or solutions containing a material where the hazard to humans is significantly different from that of the pure material or where no hazard to humans is posed, the material may be described using an alternative shipping name that represents the hazards posed by the material. An appropriate alternate proper shipping name and hazard class may be authorized by the DOT Associate Administrator.

Hazard class or Division: 8

8: Corrosive material. See 49 CFR section 173.136 for definitions.

Identification Number: UN1810
Packing Group: II

II: Packing Group II - indicates the degree of danger presented by the material is medium.

Label(s) required (if not excepted): 8, 6.1

8: Corrosive.
6.1: Poison Inhalation Hazard (inhalation hazard, Zone A or B) or Poison (other than inhalation hazard, Zone A or B; the packing group for a material is indicated in column 5 of the table.).

Special Provisions: 2, B9, B14, B32, B74, B77, N34, T20, TP2, TP38, TP45

2: This material is poisonous by inhalation (see sxn. 171.8 of this subchapter) in Hazard Zone B (see sxn. 173.116(a) or sxn. 173.133(a) of this subchapter), and must be described as an inhalation hazard under the provisions of this subchapter.
B9: Bottom outlets are not authorized.
B14: Each bulk packaging, except a tank car or a multi-unit-tank car tank, must be insulated with an insulating material so that the overall thermal conductance at 15.5 °C (60 °F) is no more than 1.5333 kilojoules per hour per square meter per degree Celsius (0.075 Btu per hour per square foot per degree Fahrenheit) temperature differential. Insulating materials must not promote corrosion to steel when wet.
B32: MC 312, MC 330, MC 331, DOT 412 cargo tanks and DOT 51 portable tanks must be made of stainless steel, except that steel other than stainless steel may be used in accordance with the provisions of sxn. 173.24b(b) of this subchapter. Thickness of stainless steel for tank shell and heads for cargo tanks and portable tanks must be the greater of 6.35 mm (0.250 inch) or the thickness required for a tank with a design pressure at least equal to 1.3 times the vapor pressure of the lading at 46 °C (115 °F). In addition, MC 312 and DOT 412 cargo tank motor vehicles must: a. Be ASME Code (U) stamped for 100% radiography of all pressure-retaining welds; b. Have accident damage protection which conforms with sxn. 178.345-8 of this subchapter; c. Have a MAWP or design pressure of at least 87 psig; and d. Have a bolted manway cover.
B74: Tank cars must have a test pressure of 20.68 Bar (300 psig) or greater and conform to Class 105S, 106, 110, 112J, 114J or 120S.
B77: Other packaging are authorized when approved by the Associate Administrator.
N34: Aluminum construction materials are not authorized for any part of a packaging which is normally in contact with the hazardous material.
T20: Minimum test pressure (bar): 10; Minimum shell thickness (in mm-reference steel) (See sxn.178.274(d)): 8 mm; Pressure-relief requirements (See sxn.178.275(g)): sxn. 178.275(g)(3); Bottom opening requirements (See sxn.178.275(d)): Prohibited.
TP2: a. The maximum degree of filling must not exceed the degree of filling determined by the following: [Degree of filling = 95/1+alpha(tr - tf)], where tr is the maximum mean bulk temperature during transport, tf is the temperature in degrees celsius of the liquid during filling, and alpha is the mean coefficient of cubical expansion of the liquid between the mean temperature of the liquid during filling (tf) and the maximum mean bulk temperature during transportation (tr) both in degrees celsius; and b. For liquids transported under ambient conditions a may be calculated using the formula: [alpha = (d15-d50)/(35 x d50)], where d15 and d50 are the densities (in units of mass per unit volume) of the liquid at 15 degrees C (59 degrees F) and 50 degrees C (122 degrees F), respectively.
TP38: Each portable tank must be insulated with an insulating material so that the overall thermal conductance at 15.5 °C (60 °F) is no more than 1.5333 kilojoules per hour per square meter per degree Celsius (0.075 Btu per hour per square foot per degree Fahrenheit) temperature differential. Insulating materials may not promote corrosion to steel when wet.
TP45: Each portable tank must be made of stainless steel, except that steel other than stainless steel may be used in accordance with the provisions of 173.24b(b) of this subchapter. Thickness of stainless steel for portable tank shells and heads must be the greater of 6.35 mm (0.250 inch) or the thickness required for a portable tank with a design pressure at least equal to 1.3 times the vapor pressure of the hazardous material at 46 °C (115 °F).

Packaging Authorizations (refer to 49 CFR 173.***):

Exceptions: None
Non-bulk packaging: 227
Bulk packaging: 244

Quantity Limitations:

Passenger aircraft or railcar: Forbidden
Cargo aircraft only: Forbidden

Vessel Stowage Requirements:

Vessel stowage location: C

C: The material must be stowed "on deck only" on a cargo vessel and on a passenger vessel.

Vessel stowage other: 40

40: Stow "clear of living quarters".

ICAO International Shipping Name for UN1810 (ICAO, 2002):

Proper Shipping Name: Phosphorus oxychloride
UN Number: 1810

LABELS

NFPA

NFPA Hazard Ratings for CAS10025-87-3 (NFPA, 2002):

Not Listed

-HANDLING AND STORAGE

HANDLING

It is recommended that personnel either handle phosphorus oxychloride from behind a body shield and in an adequate draft or outdoors in an area enclosed with a protective fence (ITI, 1988).

STORAGE

CONTAINER

The following are the usual shipping containers for phosphorus oxychloride: bottles, cans, drums, tanks on trucks, rail cars, and barges (NFPA, 1994).
ITI (1988) recommends storing the compound in vacuum containers to avoid exposure to moist air.
Ensure that containers are kept tightly closed (Budavari, 1996).

ROOM/CABINET RECOMMENDATIONS

Store phosphorus oxychloride in a cool, dry, well-ventilated area (NFPA, 1994).
Keep separate from water, acids, alkalis, alkali metals, and alcohols (NFPA, 1994).

-PERSONAL PROTECTION

SUMMARY

RECOMMENDED PROTECTIVE CLOTHING - EMERGENCY RESPONSE GUIDEBOOK, GUIDE 137 (ERG, 2004)

Wear positive pressure self-contained breathing apparatus (SCBA).
Wear chemical protective clothing that is specifically recommended by the manufacturer. It may provide little or no thermal protection.
Structural firefighters' protective clothing provides limited protection in fire situations ONLY; it is not effective in spill situations where direct contact with the substance is possible.

EYE/FACE PROTECTION

To prevent contact with eyes, wear appropriate eye protection (NIOSH , 1997).

Wear protective safety goggles (OHM/TADS , 1997).

Eyewash fountains should be provided in areas where personnel may be exposed to the chemical (NIOSH , 1997).

RESPIRATORY PROTECTION

Refer to "Recommendations for respirator selection" in the NIOSH Pocket Guide to Chemical Hazards on TOMES Plus(R) for respirator information.

PROTECTIVE CLOTHING

CHEMICAL PROTECTIVE CLOTHING. Search results for CAS 10025-87-3.

All data are compiled from published sources and are NOT recommended specifically by Truven Health Analytics. The appearance of specific manufacturers or products in this section does not represent an endorsement by Truven Health Analytics. No attempt has been made to verify the data presented. All product recommendations should be confirmed with the specific manufacturer for verification of product performance.
CLOTHING

Neoprene

River City

Neoprene splash suits

Degradation Rating: Not Recommended
Breakthrough Time (minutes): Not Listed
Permeation Rate (mcg/cm2/min): Not Listed
Notes: Not Listed
Citation: (River City, 1995)

Plastic Laminate

DuPont Personal Protection

Responder

Degradation Rating: No Degradation Rating provided
Breakthrough Time (minutes): >480
Permeation Rate (mcg/cm2/min): None detected
Notes: Not Listed
Citation: (DuPont, 2002)

Responder Plus

Degradation Rating: No Degradation Rating provided
Breakthrough Time (minutes): >480
Permeation Rate (mcg/cm2/min): None detected
Notes: Not Listed
Citation: (DuPont, 2002)

Tychem 10,000

Degradation Rating: No Degradation Rating provided
Breakthrough Time (minutes): >480
Permeation Rate (mcg/cm2/min): 0.053
Notes: liquid
Citation: (DuPont, 2002)

Tychem 7500

Degradation Rating: No Degradation Rating provided
Breakthrough Time (minutes): Not Tested
Permeation Rate (mcg/cm2/min): Not Tested
Notes: liquid
Citation: (DuPont, 2002)

Tychem 9400

Degradation Rating: No Degradation Rating provided
Breakthrough Time (minutes): >480
Permeation Rate (mcg/cm2/min): <0.1
Notes: liquid
Citation: (DuPont, 2002)

Tychem BR

Degradation Rating: No Degradation Rating provided
Breakthrough Time (minutes): >480
Permeation Rate (mcg/cm2/min): <0.1
Notes: Not Listed
Citation: (DuPont, 2002)

Tychem F

Degradation Rating: Not Listed
Breakthrough Time (minutes): >480
Permeation Rate (mcg/cm2/min): <0.01
Notes: Not Listed
Citation: (DuPont, 2003)

Tychem LV

Degradation Rating: Not Listed
Breakthrough Time (minutes): >480
Permeation Rate (mcg/cm2/min): <0.1
Notes: Not Listed
Citation: (DuPont, 2003)

Tychem QC

Degradation Rating: No Degradation Rating provided
Breakthrough Time (minutes): Not Tested
Permeation Rate (mcg/cm2/min): Not Tested
Notes: liquid
Citation: (DuPont, 2002)

Tychem SL

Degradation Rating: No Degradation Rating provided
Breakthrough Time (minutes): Not Tested
Permeation Rate (mcg/cm2/min): Not Tested
Notes: liquid
Citation: (DuPont, 2002)

Tychem ThermoPro

Degradation Rating: No Degradation Rating provided
Breakthrough Time (minutes): >480
Permeation Rate (mcg/cm2/min): <0.01
Notes: Not Listed
Citation: (DuPont, 2003)

Tychem TK

Degradation Rating: No Degradation Rating provided
Breakthrough Time (minutes): >480
Permeation Rate (mcg/cm2/min): <0.1
Notes: Not Listed
Citation: (DuPont, 2002)
Degradation Rating: No Degradation Rating provided
Breakthrough Time (minutes): >480
Permeation Rate (mcg/cm2/min): <0.1
Notes: liquid
Citation: (DuPont, 2002)

Polyvinyl Chloride

River City

PVC splash suits

Degradation Rating: Not Recommended
Breakthrough Time (minutes): Not Listed
Permeation Rate (mcg/cm2/min): Not Listed
Notes: Not Listed
Citation: (River City, 1995)

Teflon Laminate

Mar-Mac Manufacturing, Inc.

Commander Ultrapro

Degradation Rating: No Degradation Rating provided
Breakthrough Time (minutes): >180
Permeation Rate (mcg/cm2/min): <0.1
Notes: Not Listed
Citation: (Mar-Mac Manufacturing, Inc, 1995)

FOOTWEAR

Specific recommendations and test data for this product type were not found in the available manufacturers' product literature.

GLOVES

Nitrile+Neoprene+Natural Rubber

Perfect Fit Glove Co, LLC

TRIonic 521

Degradation Rating: Not Tested
Breakthrough Time (minutes): <15
Permeation Rate (mcg/cm2/min): 4217
Notes: 0.99
Citation: (MAPA Professional, 2003)

TRIonic 522

Degradation Rating: Not Tested
Breakthrough Time (minutes): <15
Permeation Rate (mcg/cm2/min): 4217
Notes: 0.99
Citation: (MAPA Professional, 2003)

TRIonic E-194

Degradation Rating: Not Tested
Breakthrough Time (minutes): <15
Permeation Rate (mcg/cm2/min): 4217
Notes: 99%
Citation: (MAPA Professional, 2003)

TRIonic E-194BPK

Degradation Rating: Not Tested
Breakthrough Time (minutes): <15
Permeation Rate (mcg/cm2/min): 4217
Notes: 99%
Citation: (MAPA Professional, 2003)

TRIonic E-204

Degradation Rating: Not Tested
Breakthrough Time (minutes): <15
Permeation Rate (mcg/cm2/min): 4217
Notes: 0.99
Citation: (MAPA Professional, 2003)

TRIonic O-240

Degradation Rating: Not Tested
Breakthrough Time (minutes): <15
Permeation Rate (mcg/cm2/min): 4217
Notes: 99%
Citation: (MAPA Professional, 2003)

Plastic Laminate

North -- Safety 4H

Degradation Rating: No Degradation Rating provided
Breakthrough Time (minutes): >240
Permeation Rate (mcg/cm2/min): Not reported
Notes: tested at 35 degrees C; 95 degrees F
Citation: (Safety 4, 2002)
Degradation Rating: No Degradation Rating provided
Breakthrough Time (minutes): >240
Permeation Rate (mcg/cm2/min): Not reported
Notes: tested at 21 degrees C; 70 degrees F
Citation: (Safety 4, 2002)

GENERAL INFORMATION

This section provides a compilation of chemical resistance information and test data for specific protective clothing products. Chemical resistance information includes both degradation resistance ratings and permeation resistance data. This information is designed to assist in the selection of appropriate protective clothing. Only data on specific products and manufacturers are included. Generic information or recommendations are not provided since significant differences can exist in the chemical resistance for apparent similar product types.
Specific product information is organized by general product type (gloves, garments, and footwear), material type, and manufacturer. The category 'garments' may include totally encapsulating suits, splash suits, as well as other items (e.g., coveralls, jackets, and aprons). Specific manufacturers should be contacted to determine the features of available styles/models.
In addition to chemical resistance information, there are many critical variables in the selection of protective clothing which cannot be represented in this summary of the literature. Some factors to be considered in choosing protective clothing include, but are not limited to: overall clothing integrity, physical hazard resistance, durability, human factors, ease of decontamination, and cost. Overall clothing integrity refers to a specific design's ability to offer consistent protection for all clothing-covered areas of the body. Physical hazards include resisting the effects of abrasion, cuts, tears, and punctures. Human factors entail effects on wearer mobility, visibility, and hearing for garments; dexterity, tactility, and grip for gloves; ankle support and weight for footwear; and, any effect of the clothing on the function of the wearer. There are several variations in the design for gloves, garments, and footwear that affect these factors. Protective clothing must properly be sized and correctly fit the wearer to ensure its proper use and function.
As required in the U.S.A., protective clothing should be selected based on a risk assessment of the workplace. This risk assessment must account for the identification of existing as well as potential hazards and involve the recommendation of protective clothing appropriate for the identified hazards. Therefore, the recommendations in this section should not be used as the sole basis for decisions on choice of protective clothing, but rather should be used as a tool by qualified occupational health and safety professionals or other technically qualified persons in conjunction with a review of all mitigating factors. Consult the OSHA PPE Standard (29 CFR 1910.132 - 1910.138) for regulations and additional guidance regarding the selection and use of protective clothing and equipment. For general information on protective clothing selection, refer to the "PERSONAL PROTECTIVE EQUIPMENT - OSHA PUB 3077" document.
PROTECTIVE CLOTHING SELECTION

Determine the type of protective clothing item needed based on a risk assessment (e.g., gloves, garments, footwear).
For high risk situations, choose clothing that covers all parts of the body that may be exposed. In many cases, multiple clothing items will be required. Low risk situations may permit partial body protective clothing. Select protective clothing products that have reported chemical resistance data. High risk situations involving full body clothing or extended chemical contact often require permeation resistance data to determine the barrier effectiveness of materials used in the construction of clothing. Relatively low risk situations, where only splash or incidental exposure occur, may allow use of protective clothing based on degradation or penetration resistance data. Specifics on the interpretation of chemical resistance data are presented below.
Other factors must be considered in addition to chemical resistance. The selected chemical protective clothing item should offer the optimal combination of protection against identified hazards while allowing maximum function and comfort.

INTERPRETATION OF DEGRADATION RATINGS

Degradation refers to physical changes in a material as the result of chemical exposure. Degradation may become evident in visible changes, such as discoloration, swelling, delamination, deterioration, or disintegration. Degradation effects may also be measured by weight change or other changes in a material's physical properties (e.g., strength, elasticity, hardness).
Degradation resistance ratings are provided by manufacturers to rate the amount of degradation that occurs for a particular protective clothing material when contacted by a chemical. All degradation ratings are qualitative and include ratings, such as "EXCELLENT," "GOOD," "FAIR," "POOR," and "NOT RECOMMENDED." There is no standard test method for the measurement of chemical degradation resistance; therefore, manufacturer ratings may be based on different testing approaches. This makes comparison of degradation ratings between manufacturers unreliable.
The use of degradation resistance ratings alone to recommend protective clothing, particularly for high hazard situations, should be avoided. Degradation resistance testing does not directly assess the barrier quality of protective clothing, since materials can show relatively little degradation but still allow either permeation or penetration by a chemical. Degradation resistance ratings can be used to exclude protective clothing materials from consideration. Protective clothing materials with a "NOT RECOMMENDED" degradation resistance rating should never be used.
For some products, the rating "NO PENETRATION" is provided. This refers to penetration resistance test results that are based on a different procedure (American Society for Testing and Materials (ASTM) Standard Test Method F 903). Penetration resistance testing involves placing a material sample in a test cell, exposing the exterior side of the material to a chemical, and then observing the interior side of the material for visible signs of liquid penetration. Part of the test is conducted at an elevated pressure. Test results are reported as pass (no penetration) or fail (penetration detected). Unlike degradation testing, penetration testing provides an assessment of protective clothing material barrier performance. Since penetration resistance testing examines only observable amounts of liquid penetration, permeation may still occur. The use of penetration resistance data must be restricted to liquid chemicals, and should be limited to scenarios where there is no reasonable vapor exposure hazard under the conditions of exposure.

INTERPRETATION OF PERMEATION DATA

Permeation is the process of chemical movement through a material on a molecular level. Permeation resistance refers to the ability of a material to retard or prevent chemical movement through it. Permeation may occur without any visible signs of degradation.
Permeation resistance is measured using a test cell which is divided into two halves by a protective clothing specimen. Chemical is placed on the challenge side, while the collection side is periodically monitored for permeating chemical. Permeation data were obtained in accordance with the American Society for Testing and Materials (ASTM) Standard Test Method F 739 (Resistance of Materials Used in Protective Clothing to Permeation by Liquids and Gases), unless stated otherwise. In the case of chemicals that are classified as warfare agents, the data were obtained in accordance with the Military Standard 282 (MIL-STD-282) (Military Standard, Filter Units, Protective Clothing, Gas-Mask Components, and Related Products: Performance Test Methods).
Permeation rate is the amount of chemical that passes through a material for a measured surface area per unit time. In this section, permeation rate is expressed in micrograms per square centimeter per minute (mcg/cm(2)/min). The reported permeation rate is either the steady-state rate or the maximum rate observed during testing. In some cases, very large permeation rates exceed measurement techniques and are reported as ">" (greater than) or "HIGH."
Breakthrough time is the elapsed time, in minutes, from the time the chemical comes in contact with the material exterior surface, to the time that chemical is detected on the interior surface. When no breakthrough is detected, the breakthrough time is report as ">" the testing period. If permeation breakthrough is rapid, results are reported as "<" (less than) the earlier sampling time or as "IMMEDIATELY" (which usually means breakthrough in less than 4 minutes).
The breakthrough time should exceed the expected use period of the selected protective clothing. Additionally, there are several other factors that must be taken into account to provide appropriate protection.
Permeation testing is usually conducted with full strength, undiluted chemical for the duration of the test period. Actual exposures may involve diluted chemical for short or intermittent exposure periods.
Permeation testing is usually conducted at room temperature. Permeation occurs faster at elevated temperatures (short breakthrough times and higher permeation rates) and slower at reduced temperatures (long breakthrough times and lower permeation rates).
Permeation resistance of mixtures cannot usually be determined on the basis of the individual chemicals making up the mixture. Synergistic effects may occur and result in more rapid permeation than accounted for by the individual mixture chemicals.
Permeation rates may be used to calculate potential wearer exposure; however, several assumptions must be made about the extent of exposure and condition of clothing wear. Furthermore, there are few chemicals with dermal exposure limits, making it difficult to determine an acceptable skin exposure level.

COMPANY INFORMATION

DuPont Personal Protection P. O. Box 80705 Wilmington, DE 19880-0705 USA Phone: (302) 774-1000 Toll-Free: (800) 931-3456 Website: http://personalprotection.dupont.com Email: personalprotection@usa.dupont.com
Mar-Mac Manufacturing, Inc. P. O. Box P.O. Box 278 McBee, SC 29101 USA Phone: (843) 335-8211 Fax: (843) 355-8599 Toll-Free: (843) 335-8211 Website: http://www.marmac.com Email: info@marmac.com
North -- Safety 4H 2000 Plainfield Pike Cranston, RI 02921 USA Phone: (800) 430-4110 Fax: (800) 572-6346 Toll-Free: (800) 430-4110 Website: http://www.safety4.com
Perfect Fit Glove Co, LLC 85 Innsbruck Dr. Buffalo, NY 14227 USA Phone: (800) 245-6837 Fax: (716) 668-3224 Toll-Free: (800) 245-6837 Website: http://www.perfectfitglove.com Email: perfectfitglove@perfectfitglove.com
River City 5321 East Shelby Dr. Memphis, TN 38188 USA Phone: (800) 888-0347 Fax: (901) 795-3815 Toll-Free: (800) 888-0347 Website: http://www.protectivewear.com Email: support@protectivewear.com

REFERENCES

CHEMICAL PROTECTIVE CLOTHING CITATIONS

The following sources were consulted for chemical protective clothing data:

(Ansell-Edmont, 2001)
(Bata Shoe Company, 1995)
(Best Manufacturing, 2002)
(Best Manufacturing, 2004)
(Boss Manufacturing Company, 1998)
(ChemFab Corporation, 1993)
(Comasec Safety, Inc., 2003)
(Comasec Safety, Inc., 2003a)
(DuPont, 2002)
(DuPont, 2002)
(DuPont, 2003)
(Guardian Manufacturing Group, 2001)
(ILC Dover, Inc., 1998)
(Kappler Inc., 2001)
(Kimberly-Clark, 2002)
(LaCrosse-Rainfair, 1997)
(MAPA Professional, 2003)
(MAPA Professional, 2004)
(Mar-Mac Manufacturing, Inc, 1995)
(Marigold Industrial, 2003)
(Memphis Glove Company, 2001)
(Montgomery Safety Products, 1995)
(Nat-Wear, 2001)
(Neese Industries, Inc., 2003)
(North, 2002)
(North, 2002)
(Playtex, 1995)
(River City, 1995)
(Safety 4, 2002)
(Servus, 1995)
(Standard Safety Equipment, 1995)
(Tingley, 2002)
(Trelleborg-Viking, Inc., 2001)
(Trelleborg-Viking, Inc., 2002)
(Wells Lamont Industrial, 2002)
(Workrite, 1997)

-PHYSICAL HAZARDS

FIRE HAZARD

SUMMARY

POTENTIAL FIRE OR EXPLOSION HAZARDS - EMERGENCY RESPONSE GUIDEBOOK, GUIDE 137 (ERG, 2004)
- EXCEPT FOR ACETIC ANHYDRIDE (UN1715), THAT IS FLAMMABLE, some of these materials may burn, but none ignite readily.
- May ignite combustibles (wood, paper, oil, clothing, etc.).
- Substance will react with water (some violently), releasing corrosive and/or toxic gases.
- Flammable/toxic gases may accumulate in confined areas (basement, tanks, hopper/tank cars etc.)
- Contact with metals may evolve flammable hydrogen gas.
- Containers may explode when heated or if contaminated with water.
- Substance may be transported in a molten form.
If phosphorus oxychloride is involved in a fire, hydrogen chloride and phosphoric acid are possible byproducts (NFPA, 1994).
Phosphorus oxychloride is not combustible, but a potentially explosive reaction with water will evolve hydrogen chloride and phosphine, which will ignite (Lewis, 1996).

FLAMMABILITY CLASSIFICATION

NFPA Flammability Rating for CAS10025-87-3 (NFPA, 2002):

Not Listed

FIRE CONTROL/EXTINGUISHING AGENTS

FIRE PRECAUTIONS - EMERGENCY RESPONSE GUIDEBOOK, GUIDE 137 (ERG, 2004)

When material is not involved in fire: do not use water on material itself.

SMALL FIRE PRECAUTIONS - EMERGENCY RESPONSE GUIDEBOOK, GUIDE 137 (ERG, 2004)

Dry chemical or CO2.
Move containers from fire area if you can do it without risk.

LARGE FIRE PRECAUTIONS - EMERGENCY RESPONSE GUIDEBOOK, GUIDE 137 (ERG, 2004)

Flood fire area with large quantities of water, while knocking down vapors with water fog. If insufficient water supply: knock down vapors only.

TANK OR CAR/TRAILER LOAD FIRE PRECAUTIONS - EMERGENCY RESPONSE GUIDEBOOK, GUIDE 137 (ERG, 2004)

Cool containers with flooding quantities of water until well after fire is out.
Do not get water inside containers.
Withdraw immediately in case of rising sound from venting safety devices or discoloration of tank.
ALWAYS stay away from tanks engulfed in fire.

NFPA Extinguishing Methods for CAS10025-87-3 (NFPA, 2002):

Not Listed

If phosphorus oxychloride is involved in a fire, use dry chemical, dry sand, or carbon dioxide (AAR, 1994).

Avoid using water on the material itself (AAR, 1994).

Use flooding quantities of water as spray or fog if large amounts of combustibles are involved in fire (AAR, 1994).

To knock down vapors, use water spray (AAR, 1994).

COMBUSTION TOXICITY

When phosphorus oxychloride is heated to decomposition, it emits extremely toxic vapors of chlorides and phosphorus oxides (Lewis, 1996).
Possible byproducts of a fire involving phosphorus oxychloride are hydrogen chloride and phosphoric acid (NFPA, 1994).
When heated (or when in contact with water), poisonous and corrosive gases are generated (CHRIS , 1997).

EXPLOSION HAZARD

When the compound comes into contact with water, an explosive reaction may result, evolving hydrogen chloride and phosphine, which will then ignite (Lewis, 1996).

An eruption of the flask contents occurred during formulation of 2,5-dimethylpyrrole using a combination of dimethylformamide and phosphorus oxychloride (Urben, 1995).

"In a chlorination reaction using phosphoryl chloride (phosphorus oxychloride) with dimethylaniline as acid acceptor, the reagents were added all at once. After an induction period, most of the mixture was ejected from the flask. On a smaller scale, the reaction had been uneventful" (Urben, 1995).

This compound forms an explosive reaction with (Lewis, 1996):

2,6-Dimethylpyridine N-oxide
Dimethyl sulfoxide
Ferrocene-1,1'-dicarboxylic acid
Pyridine N-oxide (above 60 degrees C)
Sodium + heat

DUST/VAPOR HAZARD

Phosphorus oxychloride vapor may be fatal if inhaled (NFPA, 1994).

Phosphorus oxychloride is toxic by inhalation (Lewis, 1993). It is highly irritating to eyes, skin, and mucous membranes, and inhalation may cause pulmonary edema (NFPA, 1994).

REACTIVITY HAZARD

When heated to decomposition, phosphorus oxychloride emits toxic chloride gases and oxides of phosphorus (Lewis, 1996).

Phosphorus oxychloride will react with water or steam to produce heat as well as toxic and corrosive fumes (Lewis, 1996).

The products of phosphorus oxychloride's reaction with water will corrode steel and most metals very quickly, with the resulting formation of hydrogen gas, which is flammable (Davis, 1993).

Phosphorus oxychloride is not combustible, but if involved in a fire it decomposes to produce hydrogen chloride and phosphoric acid (NFPA, 1994).

It reacts violently with water, acids, alkalis, alkali metals, and alcohols (NFPA, 1994).

An eruption of the flask contents occurred during formulation of 2,5-dimethylpyrrole using a combination of dimethylformamide and phosphorus oxychloride (Urben, 1995).

"In a chlorination reaction using phosphoryl chloride (phosphorus oxychloride) with dimethylaniline as acid acceptor, the reagents were added all at once. After an induction period, most of the mixture was ejected from the flask. On a smaller scale, the reaction had been uneventful" (Urben, 1995).

Violent reaction or ignition occurs with (Lewis, 1996):

Boron triiodide
Carbon disulfide
2,5-Dimethyl pyrrole + dimethyl formamide
Organic matter
Zinc powder

An explosive reaction can occur when water comes in contact with phosphorus oxychloride. Such a reaction evolves hydrogen chloride and phosphine, which can then ignite (Lewis, 1996).

This compound forms an explosive reaction with (Lewis, 1996):

2,6-Dimethylpyridine N-oxide
Dimethyl sulfoxide
Ferrocene-1,1'-dicarboxylic acid
Pyridine N-oxide (above 60 degrees C)
Sodium + heat

The compound corrodes tissue and metals, except nickel and lead (Davis, 1993).

Phosphorus oxychloride is generally incompatible with (Lewis, 1996):

Carbon disulfide
N,N-Dimethyl-formamide
2,5-Dimethylpyrrole
2,6-Dimethylpyridine N-oxide
Dimethylsulfoxide
Ferrocene-1,1'-dicarboxylic acid
Water
Zinc

EVACUATION PROCEDURES

SUMMARY

Initial Isolation and Protective Action Distances (ERG, 2004)

Data presented from the Emergency Response Guidebook Table of Initial Isolation and Protective Action Distances are for use when a spill has occurred and there is no fire. If there is a fire, or if a fire is involved, evacuation information presented under FIRE - PUBLIC SAFETY EVACUATION DISTANCES should be used.
Generally, a small spill is one that involves a single, small package such as a drum containing up to approximately 200 liters, a small cylinder, or a small leak from a large package. A large spill is one that involves a spill from a large package, or multiple spills from many small packages.
Suggested distances to protect from vapors of toxic-by-inhalation and/or water-reactive materials during the first 30 minutes following the spill.

DOT ID No. 1810 - Phosphorus oxychloride

when spilled on land
SMALL SPILLS

First isolate in all directions: 30 meters (100 feet).
Note wind direction.
Then protect persons downwind:

during the DAY for: 0.2 kilometers (0.2 miles); or
during the NIGHT for: 0.4 kilometers (0.3 miles).

LARGE SPILLS

First isolate in all directions: 120 meters (400 feet).
Note wind direction.
Then protect persons downwind:

during the DAY for: 1 kilometers (0.7 miles); or
during the NIGHT for: 2.2 kilometers (1.4 miles).

CAUTION:

This material which produces large amounts of the following gas(es)when spilled in water:

Hydrogen chloride

DOT ID No. 1810 - Phosphorus oxychloride

when spilled in water
SMALL SPILLS

First isolate in all directions: 30 meters (100 feet).
Note wind direction.
Then protect persons downwind:

during the DAY for: 0.2 kilometers (0.1 miles); or
during the NIGHT for: 1 kilometers (0.6 miles).

LARGE SPILLS

First isolate in all directions: 240 meters (800 feet).
Note wind direction.
Then protect persons downwind:

during the DAY for: 2.3 kilometers (1.5 miles); or
during the NIGHT for: 6.3 kilometers (3.9 miles).

CAUTION:

This material which produces large amounts of the following gas(es)when spilled in water:

Hydrogen chloride

SPILL - PUBLIC SAFETY EVACUATION DISTANCES - EMERGENCY RESPONSE GUIDEBOOK, GUIDE 137 (ERG, 2004)

Increase, in the downwind direction, as necessary, the isolation distance of at least 50 meters (150 feet) for liquids and 25 meters (75 feet) for solids in all directions.

FIRE - PUBLIC SAFETY EVACUATION DISTANCES - EMERGENCY RESPONSE GUIDEBOOK, GUIDE 137 (ERG, 2004)

If tank, rail car or tank truck is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions.

PUBLIC SAFETY MEASURES - EMERGENCY RESPONSE GUIDEBOOK, GUIDE 137 (ERG, 2004)

CALL Emergency Response Telephone Number on Shipping Paper first. If Shipping Paper not available or no answer, refer to appropriate telephone number:

MEXICO:

SETIQ:

01-800-00-214-00 in the Mexican Republic;
For calls originating in Mexico City and the Metropolitan Area: 5559-1588;
For calls originating elsewhere, call: 011-52-555-559-1588.

CENACOM:

01-800-00-413-00 in the Mexican Republic;
For calls originating in Mexico City and the Metropolitan Area: 5550-1496, 5550-1552, 5550-1485, or 5550-4885;
For calls originating elsewhere, call: 011-52-555-550-1496, or 011-52-555-550-1552; 011-52-555-550-1485, or 011-52-555-550-4885.

ARGENTINA:

CIQUIME:

0-800-222-2933 in the Republic of Argentina;
For calls originating elsewhere, call: +54-11-4613-1100.

BRAZIL:

PRÓ-QUÍMICA:

0-800-118270 (Toll-free in Brazil);
For calls originating elsewhere, call: +55-11-232-1144 (Collect calls are accepted).

COLUMBIA:

CISPROQUIM:

01-800-091-6012 in Colombia;
For calls originating in Bogotá, Colombia, call: 288-6012;
For calls originating elsewhere, call: 011-57-1-288-6012.

CANADA:

CANUTEC:

613-996-6666 (Collect calls are accepted);
*666 cellular (in Canada only).

UNITED STATES:

CHEMTREC®:

1-800-424-9300 (Toll-free in the U.S., Canada, and the U.S. Virgin Islands);
703-527-3887 for calls originating elsewhere (Collect calls are accepted).

CHEM-TEL, INC.:

1-800-255-3924 (Toll-free in the U.S., Canada, and the U.S. Virgin Islands);
813-248-0585 for calls originating elsewhere (Collect calls are accepted).

INFOTRAC:

1-800-535-5053 (Toll-free in the U.S., Canada, and the U.S. Virgin Islands);
352-323-3500 for calls originating elsewhere (Collect calls are accepted).

3E COMPANY:

1-800-451-8346 (Toll-free in the U.S., Canada, and the U.S. Virgin Islands);
760-602-8703 for calls originating elsewhere (Collect calls are accepted).

NATIONAL RESPONSE CENTER (NRC):

1-800-424-8802 - (24 hours) (Toll-free in the U.S., Canada, and the U.S. Virgin Islands);
202-267-2675 for calls in the District of Columbia.

MILITARY SHIPMENTS:

703-697-0218 - Explosives/ammunition incidents (Collect calls are accepted);
1-800-851-8061 - All other dangerous goods incidents.

NATIONWIDE POISON CONTROL CENTER (United States only):

1-800-222-1222 (Toll-free in the U.S.).

For additional details see the section entitled "WHO TO CALL FOR ASSISTANCE" under the ERG Instructions.
As an immediate precautionary measure, isolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids.
Keep unauthorized personnel away.
Stay upwind.
Keep out of low areas.
Ventilate enclosed areas.

AIHA ERPG Values for CAS10025-87-3 (AIHA, 2006):

Not Listed

DOE TEEL Values for CAS10025-87-3 (U.S. Department of Energy, Office of Emergency Management, 2010):

Listed as Phosphorus oxychloride
TEEL-0 (units = ppm): 0.1
TEEL-1 (units = ppm): 0.479
TEEL-2 (units = ppm): 0.479
TEEL-3 (units = ppm): 0.85
Definitions:

TEEL-0: The threshold concentration below which most people will experience no adverse health effects.
TEEL-1: The airborne concentration (expressed as ppm [parts per million] or mg/m(3) [milligrams per cubic meter]) of a substance above which it is predicted that the general population, including susceptible individuals, could experience notable discomfort, irritation, or certain asymptomatic, nonsensory effects. However, these effects are not disabling and are transient and reversible upon cessation of exposure.
TEEL-2: The airborne concentration (expressed as ppm or mg/m(3)) of a substance above which it is predicted that the general population, including susceptible individuals, could experience irreversible or other serious, long-lasting, adverse health effects or an impaired ability to escape.
TEEL-3: The airborne concentration (expressed as ppm or mg/m(3)) of a substance above which it is predicted that the general population, including susceptible individuals, could experience life-threatening adverse health effects or death.

AEGL Values for CAS10025-87-3 (National Research Council, 2010; National Research Council, 2009; National Research Council, 2008; National Research Council, 2007; NRC, 2001; NRC, 2002; NRC, 2003; NRC, 2004; NRC, 2004; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2006; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2007; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2005; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2005; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2007; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2006; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2006; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2006; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2006; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2006; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2006; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2006; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2006; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2006; United States Environmental Protection Agency Office of Pollution Prevention and Toxics, 2006; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2006; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2007; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2007; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2007; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2007; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2007; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2009; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2009; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2009; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2009; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2009; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2009; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2009; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2009; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2009; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2009; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2009; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2009; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2009; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2007; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2006; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2006; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2006; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2007; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2007; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2007; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2007; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2007; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2005; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2005; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2005; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2005; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2005; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2005; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2005; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2005; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2007; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2005; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2006; 62 FR 58840, 1997; 65 FR 14186, 2000; 65 FR 39264, 2000; 65 FR 77866, 2000; 66 FR 21940, 2001; 67 FR 7164, 2002; 68 FR 42710, 2003; 69 FR 54144, 2004):

Listed as: Phosphorus oxychloride
Proposed Value:

AEGL-1

10 min exposure:

ppm: Not Recommended
mg/m3: Not Recommended

30 min exposure:

ppm: Not Recommended
mg/m3: Not Recommended

1 hr exposure:

ppm: Not Recommended
mg/m3: Not Recommended

4 hr exposure:

ppm: Not Recommended
mg/m3: Not Recommended

8 hr exposure:

ppm: Not Recommended
mg/m3: Not Recommended

Definitions:

AEGL-1 is the airborne concentration of a substance above which it is predicted that the general population, including susceptible individuals, could experience notable discomfort, irritation, or certain asymptomatic non-sensory effects. However, the effects are not disabling, are transient, and are reversible upon cessation of exposure.

Listed as: Phosphorus oxychloride
Proposed Value:

AEGL-2

10 min exposure:

ppm: Not Recommended
mg/m3: Not Recommended

30 min exposure:

ppm: Not Recommended
mg/m3: Not Recommended

1 hr exposure:

ppm: Not Recommended
mg/m3: Not Recommended

4 hr exposure:

ppm: Not Recommended
mg/m3: Not Recommended

8 hr exposure:

ppm: Not Recommended
mg/m3: Not Recommended

Definitions:

AEGL-2 is the airborne concentration of a substance above which it is predicted that the general population, including susceptible individuals, could experience irreversible or other serious, long-lasting adverse health effects or an impaired ability to escape.

Listed as: Phosphorus oxychloride
Proposed Value:

AEGL-3

10 min exposure:

ppm: 1.1 ppm
mg/m3: 6.9 mg/m(3)

30 min exposure:

ppm: 1.1 ppm
mg/m3: 6.9 mg/m(3)

1 hr exposure:

ppm: 0.85 ppm
mg/m3: 5.3 mg/m(3)

4 hr exposure:

ppm: 0.54 ppm
mg/m3: 3.4 mg/m(3)

8 hr exposure:

ppm: 0.27 ppm
mg/m3: 1.7 mg/m(3)

Definitions:

AEGL-3 is the airborne concentration of a substance above which it is predicted that the general population, including susceptible individuals, could experience life-threatening health effects or death.

NIOSH IDLH Values for CAS10025-87-3 (National Institute for Occupational Safety and Health, 2007):

Not Listed

CONTAINMENT/WASTE TREATMENT OPTIONS

SUMMARY

SPILL OR LEAK PRECAUTIONS - EMERGENCY RESPONSE GUIDEBOOK, GUIDE 137 (ERG, 2004)
- Fully encapsulating, vapor protective clothing should be worn for spills and leaks with no fire.
- Do not touch damaged containers or spilled material unless wearing appropriate protective clothing.
- Stop leak if you can do it without risk.
- Use water spray to reduce vapors; do not put water directly on leak, spill area or inside container.
- Keep combustibles (wood, paper, oil, etc.) away from spilled material.
RECOMMENDED PROTECTIVE CLOTHING - EMERGENCY RESPONSE GUIDEBOOK, GUIDE 137 (ERG, 2004)
- Wear positive pressure self-contained breathing apparatus (SCBA).
- Wear chemical protective clothing that is specifically recommended by the manufacturer. It may provide little or no thermal protection.
- Structural firefighters' protective clothing provides limited protection in fire situations ONLY; it is not effective in spill situations where direct contact with the substance is possible.
LAND SPILL (AAR, 1994)
- To contain the spill, dig a pit, pond, lagoon, or holding area.
- Use soil, sandbags, foamed polyurethane, or foamed concrete to dike surface flow of material.
- Use fly ash or cement powder to absorb bulk liquid.
- Neutralize the spill by using agricultural lime (CaO), crushed limestone (CaCO3) or sodium bicarbonate (NaHCO3).
WATER SPILL (AAR, 1994)
- Use agricultural lime (CaO), crushed limestone (CaCO3), or sodium bicarbonate (NaHCO3) to neutralize the spill.
- To remove immobilized amounts of pollutants and precipitates, use mechanical lifts or dredges.
- Adjust spill pH to neutral (neutral pH = 7).
AIR RELEASE/SPILL (AAR, 1994)
- Knock down vapor using water spray or mist.
- Water used to knock down vapors is corrosive or toxic and should be diked for containment.
In high concentrations, phosphorus oxychloride is dangerous to aquatic life and may be hazardous if it enters water intakes. If such a spill occurs, notify health and wildlife officials as well as nearby water intake operators (CHRIS , 1997).

SMALL LEAK/SPILL

SMALL SPILL PRECAUTIONS - EMERGENCY RESPONSE GUIDEBOOK, GUIDE 137 (ERG, 2004)
- Cover with DRY earth, DRY sand or other non-combustible material followed with plastic sheet to minimize spreading or contact with rain.
- Use clean non-sparking tools to collect material and place it into loosely covered plastic containers for later disposal.
- Prevent entry into waterways, sewers, basements or confined areas.

LARGE LEAK/SPILL

For a large spill, neutralization with lime or sodium carbonate is possible but risky; it is best to ship material back to the supplier for reprocessing. For assistance, call the supplier (OHM/TADS , 1997).

WASTE TREATMENT OPTIONS

CHEMICAL TREATMENT

To manage and dispose of a spill, cover with sodium carbonate or calcium carbonate, bentonite (clay cat litter), and sand in a 1:1:1 mixture by weight. After absorption of phosphorus oxychloride, scoop the material into a plastic pail and, while under a fume hood, add the mixture very slowly to a pail of cold water and leave standing for 24 hours. Test the solution's pH and, if necessary, neutralize with sodium carbonate (Armour, 1996).
To dispose of small quantities, do the following while under a fume hood: move the material into an evaporating dish and then cover with large quantities of solid sodium carbonate or calcium carbonate. When the reaction stops, add the mixture very slowly to a pail of cold water. Then allow to stand for 24 hours. After testing the pH, neutralize, if necessary, with sodium carbonate or 5% sodium hydroxide solution (Armour, 1996).
For a small spill, move material into an evaporating dish that contains sodium bicarbonate; while stirring, spray the mixture with ammonia and then spread with crushed ice; continue to spray with ammonia until the ammonium chloride smoke partly subsides; then add iced water while stirring (ITI, 1988).
Waste management activities associated with material disposition are unique to individual situations. Proper waste characterization and decisions regarding waste management should be coordinated with the appropriate local, state, or federal authorities to ensure compliance with all applicable rules and regulations.

-ENVIRONMENTAL HAZARD MANAGEMENT

POLLUTION HAZARD

Occupational exposure to phosphorus oxychloride may involve workers manufacturing or working with acetyl cellulose; bronze alloy; munitions; smoke bombs and incendiaries; pesticide/rat poison; fertilizer; or electroluminescent-coatings (HSDB, 2003).

ENVIRONMENTAL FATE AND KINETICS

WATER

SURFACE WATER
- If discharged to water, a considerable delay may occur before an exothermal hydrolysis reaction occurs. When the reaction is vigorous enough, steam and the liberation of hydrogen chloride gas result. It is possible that a dense and cold layer of phosphorus oxychloride may exist for several minutes under water before violent and instantaneous hydrolysis occurs (Urben, 1995).

ENVIRONMENTAL TOXICITY

This compound, in high concentrations, is dangerous to aquatic life (CHRIS , 1997).

-PHYSICAL/CHEMICAL PROPERTIES

MOLECULAR WEIGHT

153.35 (Budavari, 1996)

DESCRIPTION/PHYSICAL STATE

Phosphorus oxychloride is a colorless to yellow, clear, strongly fuming liquid. Its odor is musty and pungent (NIOSH , 1997; Budavari, 1996).

VAPOR PRESSURE

40 mmHg (at 27.3 degrees C) (Lewis, 1996)

100 mmHg (at 47.4 degrees C) (OHM/TADS , 1997)

400 mmHg (at 84.3 degrees C) (OHM/TADS , 1997)

28 mmHg (at 20 degrees C) (NFPA, 1994)

104 mmHg (at 50 degrees C) (NFPA, 1994)

DENSITY

NORMAL TEMPERATURE AND PRESSURE

(25 degrees C; 77 degrees F and 760 mmHg)
1.645 (ACGIH, 1996a; Budavari, 1996)

OTHER TEMPERATURE AND/OR PRESSURE

1.685 (at 15.5 degrees C) (Lewis, 1996)
1.68 (at 16 degrees C) (NFPA, 1994)

VAPOR DENSITY

5.3 (Lewis, 1996)
6.8518 g/L (OHM/TADS , 1997)

FREEZING/MELTING POINT

FREEZING POINT

1 degree C (NIOSH , 1997)

MELTING POINT

1.25 degrees C (Budavari, 1996)
2 degrees C (NFPA, 1994)
1.17 degrees C (OHM/TADS , 1997)
-1 degree C (Ashford, 1994)

BOILING POINT

105.8 degrees C (Budavari, 1996)

105.1 degrees C (Lewis, 1996)

107.2 degrees C (Davis, 1993)

106 degrees C (Ashford, 1994)

FLASH POINT

Not available (Davis, 1993)

EXPLOSIVE LIMITS

LOWER

Not available (Davis, 1993)

UPPER

Not available (Davis, 1993)

OTHER/PHYSICAL

CRITICAL TEMPERATURE

332 degrees C (CHRIS , 1997)

INDEX OF REFRACTION

1.460 (at 25 degrees C) (Lewis, 1993)

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PHOSPHORUS OXYCHLORIDE

Classification | Information to evaluate chemical incidents

Information to evaluate chemical incidents

Information to evaluate chemical incidents

Information to evaluate chemical incidents