PERCHLOROMETHYL MERCAPTAN

Severe respiratory tract irritation and pulmonary edema may result from inhalation exposure. Eye, nose, and throat irritation may be noted. Ingestion can cause gastrointestinal tract irritation with nausea, vomiting, diarrhea, abdominal pain, and possible mucosal ulceration.

CNS depression and seizures may occur. Renal and hepatic damage, as well as necrotizing tracheitis, have been reported in one fatal case.

POTENTIAL HEALTH HAZARDS - EMERGENCY RESPONSE GUIDEBOOK, GUIDE 157 (ERG, 2004)

TOXIC; inhalation, ingestion or contact (skin, eyes) with vapors, dusts or substance may cause severe injury, burns, or death.
Reaction with water or moist air will release toxic, corrosive or flammable gases.
Reaction with water may generate much heat which will increase the concentration of fumes in the air.
Fire will produce irritating, corrosive and/or toxic gases.
Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution.

-FIRST AID

FIRST AID AND PREHOSPITAL TREATMENT

ORAL EXPOSURE -

Due to the irritant properties of perchloromethyl mercaptan, emesis should not be induced following ingestion.
DILUTION: If no respiratory compromise is present, administer milk or water as soon as possible after ingestion. Dilution may only be helpful if performed in the first seconds to minutes after ingestion. The ideal amount is unknown; no more than 8 ounces (240 mL) in adults and 4 ounces (120 mL) in children is recommended to minimize the risk of vomiting.
Observe patients with ingestion carefully for the possible development of esophageal or gastrointestinal tract irritation or burns. If signs or symptoms of esophageal irritation or burns are present, consider endoscopy to determine the extent of injury.
SEIZURES: Administer a benzodiazepine; DIAZEPAM (ADULT: 5 to 10 mg IV initially; repeat every 5 to 20 minutes as needed. CHILD: 0.1 to 0.5 mg/kg IV over 2 to 5 minutes; up to a maximum of 10 mg/dose. May repeat dose every 5 to 10 minutes as needed) or LORAZEPAM (ADULT: 2 to 4 mg IV initially; repeat every 5 to 10 minutes as needed, if seizures persist. CHILD: 0.05 to 0.1 mg/kg IV over 2 to 5 minutes, up to a maximum of 4 mg/dose; may repeat in 5 to 15 minutes as needed, if seizures continue).

Consider phenobarbital or propofol if seizures recur after diazepam 30 mg (adults) or 10 mg (children greater than 5 years).
Monitor for hypotension, dysrhythmias, respiratory depression, and need for endotracheal intubation. Evaluate for hypoglycemia, electrolyte disturbances, and hypoxia.

Airway patency and oxygenation should be assured.

-MEDICAL TREATMENT

LIFE SUPPORT

Support respiratory and cardiovascular function.

SUMMARY

FIRST AID - EMERGENCY RESPONSE GUIDEBOOK, GUIDE 157 (ERG, 2004)

Move victim to fresh air.
Call 911 or emergency medical service.
Give artificial respiration if victim is not breathing.
Do not use mouth-to-mouth method if victim ingested or inhaled the substance; give artificial respiration with the aid of a pocket mask equipped with a one-way valve or other proper respiratory medical device.
Administer oxygen if breathing is difficult.
Remove and isolate contaminated clothing and shoes.
In case of contact with substance, immediately flush skin or eyes with running water for at least 20 minutes.
For minor skin contact, avoid spreading material on unaffected skin.
Keep victim warm and quiet.
Effects of exposure (inhalation, ingestion or skin contact) to substance may be delayed.
Ensure that medical personnel are aware of the material(s) involved and take precautions to protect themselves.

FIRST AID

INHALATION EXPOSURE - Remove victims of inhalation exposure from the toxic environment and administer 100% humidified supplemental oxygen with artificial ventilation as required.
DERMAL/OCULAR EXPOSURE - Exposed skin and eyes should be flushed with copious amounts of water.
ORAL EXPOSURE - Because of the irritant properties of perchloromethyl mercaptan, emesis should not be induced following ingestion. Immediate dilution with milk or water may be beneficial.

Patients with ingestion exposure should be carefully observed for the development of severe esophageal or gastrointestinal tract irritation, ulceration, bleeding, or perforation.

Systemic effects may be noted following ingestion or dermal contact. If central nervous system and respiratory depression occur, airway patency and oxygenation should be assured. Treat seizures with standard anticonvulsant therapy.

-RANGE OF TOXICITY

MINIMUM LETHAL EXPOSURE

ACUTE

The lowest lethal exposure for a human is 483 parts per million for 10 minutes (ITI, 1985).

CASE REPORTS

OCCUPATIONAL

Of three chemical workers with direct dermal contact as well as inhalation exposure, one died within 36 hours (Hathaway et al, 1991).

ANIMAL DATA

Cats and mice with inhalation exposure to 45 parts per million for 15 minutes died of pulmonary edema within one to two days (ACGIH, 1986; Hathaway et al, 1991).
Repeated exposures over 3 months at 1 part per million were lethal to some, but not all, mice (Hathaway et al, 1991).

MAXIMUM TOLERATED EXPOSURE

GENERAL/SUMMARY

Eye irritation is noted at 1.3 parts per million (10 milligrams per cubic meter). Humans can tolerate exposure to up to 8.8 parts per million (70 milligrams per cubic meter), but develop nausea and eye, throat, and respiratory tract irritation (Hathaway et al, 1991).

CASE REPORTS

OCCUPATIONAL

Two of three chemical workers with direct dermal contact as well as inhalation exposure developed pulmonary edema but survived (Hathaway et al, 1991).

Carcinogenicity Ratings for CAS594-42-3 :

ACGIH (American Conference of Governmental Industrial Hygienists, 2010): Not Listed ; Listed as: Perchloromethyl mercaptan
EPA (U.S. Environmental Protection Agency, 2011): Not Listed
IARC (International Agency for Research on Cancer (IARC), 2016; International Agency for Research on Cancer, 2015; IARC Working Group on the Evaluation of Carcinogenic Risks to Humans, 2010; IARC Working Group on the Evaluation of Carcinogenic Risks to Humans, 2010a; IARC Working Group on the Evaluation of Carcinogenic Risks to Humans, 2008; IARC Working Group on the Evaluation of Carcinogenic Risks to Humans, 2007; IARC Working Group on the Evaluation of Carcinogenic Risks to Humans, 2006; IARC, 2004): Not Listed
NIOSH (National Institute for Occupational Safety and Health, 2007): Not Listed ; Listed as: Perchloromethyl mercaptan
MAK (DFG, 2002): Not Listed
NTP (U.S. Department of Health and Human Services, Public Health Service, National Toxicology Project ): Not Listed

TOXICITY AND RISK ASSESSMENT VALUES

EPA IRIS

EPA Risk Assessment Values for CAS594-42-3 (U.S. Environmental Protection Agency, 2011):

Not Listed

TOXICITY VALUES

References: RTECS, 1995 Lewis, 1992 ITI, 1985
- LC50- (INHALATION)MOUSE:
- LC50- (INHALATION)RAT:
- LCLo- (INHALATION)CAT:
- LCLo- (INHALATION)MOUSE:
- LCLo- (INHALATION)RAT:
- LD50- (INTRAVENOUS)MOUSE:
- LD50- (SKIN)RABBIT:
- LD50- (ORAL)RAT:

CALCULATIONS

AMBIENT CONVERSIONS

CONVERSION FACTORS

1 part per million equals about 7.6 milligrams per cubic meter (ACGIH, 1991)

To convert parts per million to milligrams per cubic meter, multiply parts per million by 7.6.
To convert milligrams per cubic meter to parts per million, divide milligrams per cubic meter by 7.6.

-STANDARDS AND LABELS

WORKPLACE STANDARDS

ACGIH TLV Values for CAS594-42-3 (American Conference of Governmental Industrial Hygienists, 2010):

Editor's Note: The listed values are recommendations or guidelines developed by ACGIH(R) to assist in the control of health hazards. They should only be used, interpreted and applied by individuals trained in industrial hygiene. Before applying these values, it is imperative to read the introduction to each section in the current TLVs(R) and BEI(R) Book and become familiar with the constraints and limitations to their use. Always consult the Documentation of the TLVs(R) and BEIs(R) before applying these recommendations and guidelines.

Adopted Value

Perchloromethyl mercaptan

TLV:

TLV-TWA: 0.1 ppm
TLV-STEL:
TLV-Ceiling:

Notations and Endnotes:

Carcinogenicity Category: Not Listed
Codes: Not Listed
Definitions: Not Listed

TLV Basis - Critical Effect(s): Eye and URT irr
Molecular Weight: 185.87

For gases and vapors, to convert the TLV from ppm to mg/m(3):

[(TLV in ppm)(gram molecular weight of substance)]/24.45

For gases and vapors, to convert the TLV from mg/m(3) to ppm:

[(TLV in mg/m(3))(24.45)]/gram molecular weight of substance

AIHA WEEL Values for CAS594-42-3 (AIHA, 2006):

Not Listed

NIOSH REL and IDLH Values for CAS594-42-3 (National Institute for Occupational Safety and Health, 2007):

Listed as: Perchloromethyl mercaptan
REL:

TWA: 0.1 ppm (0.8 mg/m(3))
STEL:
Ceiling:
Carcinogen Listing: (Not Listed) Not Listed
Skin Designation: Not Listed
Note(s):

IDLH:

IDLH: 10 ppm
Note(s): Not Listed

OSHA PEL Values for CAS594-42-3 (U.S. Occupational Safety, and Health Administration (OSHA), 2010):

Listed as: Perchloromethyl mercaptan
Table Z-1 for Perchloromethyl mercaptan:

8-hour TWA:

ppm: 0.1

Parts of vapor or gas per million parts of contaminated air by volume at 25 degrees C and 760 torr.

mg/m3: 0.8

Milligrams of substances per cubic meter of air. When entry is in this column only, the value is exact; when listed with a ppm entry, it is approximate.

Ceiling Value:
Skin Designation: No
Notation(s): Not Listed

OSHA List of Highly Hazardous Chemicals, Toxics, and Reactives for CAS594-42-3 (U.S. Occupational Safety and Health Administration, 2010):

Threshold Quantity, in pounds:150

ENVIRONMENTAL STANDARDS

EPA CERCLA, Hazardous Substances and Reportable Quantities for CAS594-42-3 (U.S. Environmental Protection Agency, 2010):

Listed as: Trichloromethanesulfenyl chloride
Final Reportable Quantity, in pounds (kilograms):

100 (45.4)

Additional Information:
Listed as: Methanesulfenyl chloride, trichloro-
Final Reportable Quantity, in pounds (kilograms):

100 (45.4)

Additional Information:

EPA CERCLA, Hazardous Substances and Reportable Quantities, Radionuclides for CAS594-42-3 (U.S. Environmental Protection Agency, 2010):

Not Listed

EPA RCRA Hazardous Waste Number for CAS594-42-3 (U.S. Environmental Protection Agency, 2010b):

Not Listed
Editor's Note: The D, F, and K series waste numbers and Appendix VIII to Part 261 -- Hazardous Constituents were not included. Please refer to 40 CFR Part 261.

EPA SARA Title III, Extremely Hazardous Substance List for CAS594-42-3 (U.S. Environmental Protection Agency, 2010):

Listed as: Perchloromethylmercaptan
Reportable Quantity, in pounds: 100

Only the statutory or final RQ is shown. For more information, see 40 CFR table 302.4.

Threshold Planning Quantity, in pounds:

500
Amount necessary to be covered by this standard. See 40 CFR 355.30.

Note(s): Not Listed

EPA SARA Title III, Community Right-to-Know for CAS594-42-3 (40 CFR 372.65, 2006; 40 CFR 372.28, 2006):

Listed as: Perchloromethyl mercaptan
Effective Date for Reporting Under 40 CFR 372.30: 1/1/95
Lower Thresholds for Chemicals of Special Concern under 40 CFR 372.28:

DOT List of Marine Pollutants for CAS594-42-3 (49 CFR 172.101 - App. B, 2005):

Listed as Perchloromethylmercaptan
Severe Marine Pollutant: No
Listed as Trichloromethane sulphuryl chloride
Severe Marine Pollutant: No
Listed as Trichloromethyl sulphochloride
Severe Marine Pollutant: No
Listed as Thiocarbonyl tetrachloride
Severe Marine Pollutant: No

EPA TSCA Inventory for CAS594-42-3 (EPA, 2005):

Listed as: Methanesulfenyl chloride, trichloro-

SHIPPING REGULATIONS

SURFACE

DOT -- Table of Hazardous Materials and Special Provisions for UN/NA Number 1670 (49 CFR 172.101, 2005):

Hazardous materials descriptions and proper shipping name: Perchloromethyl mercaptan

Symbol(s): Not Listed
Hazard class or Division: 6.1

6.1: Poisonous materials. See 49 CFR section 173.132 for definitions.

Identification Number: UN1670
Packing Group: I

I: Packing Group I - indicates the degree of danger presented by the material is great.

Label(s) required (if not excepted): 6.1

6.1: Poison Inhalation Hazard (inhalation hazard, Zone A or B) or Poison (other than inhalation hazard, Zone A or B; the packing group for a material is indicated in column 5 of the table.).

Special Provisions: 2, B9, B14, B32, B74, N34, T20, TP2, TP13, TP38, TP45

2: This material is poisonous by inhalation (see sxn. 171.8 of this subchapter) in Hazard Zone B (see sxn. 173.116(a) or sxn. 173.133(a) of this subchapter), and must be described as an inhalation hazard under the provisions of this subchapter.
B9: Bottom outlets are not authorized.
B14: Each bulk packaging, except a tank car or a multi-unit-tank car tank, must be insulated with an insulating material so that the overall thermal conductance at 15.5 °C (60 °F) is no more than 1.5333 kilojoules per hour per square meter per degree Celsius (0.075 Btu per hour per square foot per degree Fahrenheit) temperature differential. Insulating materials must not promote corrosion to steel when wet.
B32: MC 312, MC 330, MC 331, DOT 412 cargo tanks and DOT 51 portable tanks must be made of stainless steel, except that steel other than stainless steel may be used in accordance with the provisions of sxn. 173.24b(b) of this subchapter. Thickness of stainless steel for tank shell and heads for cargo tanks and portable tanks must be the greater of 6.35 mm (0.250 inch) or the thickness required for a tank with a design pressure at least equal to 1.3 times the vapor pressure of the lading at 46 °C (115 °F). In addition, MC 312 and DOT 412 cargo tank motor vehicles must: a. Be ASME Code (U) stamped for 100% radiography of all pressure-retaining welds; b. Have accident damage protection which conforms with sxn. 178.345-8 of this subchapter; c. Have a MAWP or design pressure of at least 87 psig; and d. Have a bolted manway cover.
B74: Tank cars must have a test pressure of 20.68 Bar (300 psig) or greater and conform to Class 105S, 106, 110, 112J, 114J or 120S.
N34: Aluminum construction materials are not authorized for any part of a packaging which is normally in contact with the hazardous material.
T20: Minimum test pressure (bar): 10; Minimum shell thickness (in mm-reference steel) (See sxn.178.274(d)): 8 mm; Pressure-relief requirements (See sxn.178.275(g)): sxn. 178.275(g)(3); Bottom opening requirements (See sxn.178.275(d)): Prohibited.
TP2: a. The maximum degree of filling must not exceed the degree of filling determined by the following: [Degree of filling = 95/1+alpha(tr - tf)], where tr is the maximum mean bulk temperature during transport, tf is the temperature in degrees celsius of the liquid during filling, and alpha is the mean coefficient of cubical expansion of the liquid between the mean temperature of the liquid during filling (tf) and the maximum mean bulk temperature during transportation (tr) both in degrees celsius; and b. For liquids transported under ambient conditions a may be calculated using the formula: [alpha = (d15-d50)/(35 x d50)], where d15 and d50 are the densities (in units of mass per unit volume) of the liquid at 15 degrees C (59 degrees F) and 50 degrees C (122 degrees F), respectively.
TP13: Self-contained breathing apparatus must be provided when this hazardous material is transported by sea.
TP38: Each portable tank must be insulated with an insulating material so that the overall thermal conductance at 15.5 °C (60 °F) is no more than 1.5333 kilojoules per hour per square meter per degree Celsius (0.075 Btu per hour per square foot per degree Fahrenheit) temperature differential. Insulating materials may not promote corrosion to steel when wet.
TP45: Each portable tank must be made of stainless steel, except that steel other than stainless steel may be used in accordance with the provisions of 173.24b(b) of this subchapter. Thickness of stainless steel for portable tank shells and heads must be the greater of 6.35 mm (0.250 inch) or the thickness required for a portable tank with a design pressure at least equal to 1.3 times the vapor pressure of the hazardous material at 46 °C (115 °F).

Packaging Authorizations (refer to 49 CFR 173.***):

Exceptions: None
Non-bulk packaging: 227
Bulk packaging: 244

Quantity Limitations:

Passenger aircraft or railcar: Forbidden
Cargo aircraft only: Forbidden

Vessel Stowage Requirements:

Vessel stowage location: D

D: The material must be stowed "on deck only" on a cargo vessel and on a passenger vessel carrying a number of passengers limited to not more than the larger of 25 passengers or one passenger per each 3 m of overall vessel length, but the material is prohibited on passenger vessels in which the limiting number of passengers is exceeded.

Vessel stowage other: 40

40: Stow "clear of living quarters".

ICAO International Shipping Name for UN1670 (ICAO, 2002):

Proper Shipping Name: Perchloromethyl mercaptan
UN Number: 1670

LABELS

NFPA

NFPA Hazard Ratings for CAS594-42-3 (NFPA, 2002):

Not Listed

-PERSONAL PROTECTION

SUMMARY

RECOMMENDED PROTECTIVE CLOTHING - EMERGENCY RESPONSE GUIDEBOOK, GUIDE 157 (ERG, 2004)

Wear positive pressure self-contained breathing apparatus (SCBA).
Wear chemical protective clothing that is specifically recommended by the manufacturer. It may provide little or no thermal protection.
Structural firefighters' protective clothing provides limited protection in fire situations ONLY; it is not effective in spill situations where direct contact with the substance is possible.

RESPIRATORY PROTECTION

Refer to "Recommendations for respirator selection" in the NIOSH Pocket Guide to Chemical Hazards on TOMES Plus(R) for respirator information.

PROTECTIVE CLOTHING

CHEMICAL PROTECTIVE CLOTHING. Search results for CAS 594-42-3.

Specific recommendations and test data for this chemical were not found in the available manufacturers' product literature. A complete list of consulted manufacturers and references is presented below.

-PHYSICAL HAZARDS

FIRE HAZARD

SUMMARY

POTENTIAL FIRE OR EXPLOSION HAZARDS - EMERGENCY RESPONSE GUIDEBOOK, GUIDE 157 (ERG, 2004)
- Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes.
- Vapors may accumulate in confined areas (basement, tanks, hopper/tank cars etc.).
- Substance will react with water (some violently), releasing corrosive and/or toxic gases.
- Contact with metals may evolve flammable hydrogen gas.
- Containers may explode when heated or if contaminated with water.
Perchloromethyl mercaptan is neither flammable nor a serious fire hazard, although it will support combustion (ACGIH, 1986).
Toxic gases and vapors, such as carbon tetrachloride, hydrogen sulfide, sulfur dioxide, and carbon monoxide, may be released in fires involving perchloromethyl mercaptan (HSDB , 1992).

FLAMMABILITY CLASSIFICATION

NFPA Flammability Rating for CAS594-42-3 (NFPA, 2002):

Not Listed

FIRE CONTROL/EXTINGUISHING AGENTS

FIRE PRECAUTIONS - EMERGENCY RESPONSE GUIDEBOOK, GUIDE 157 (ERG, 2004)

Note: Most foams will react with the material and release corrosive/toxic gases.

SMALL FIRE PRECAUTIONS - EMERGENCY RESPONSE GUIDEBOOK, GUIDE 157 (ERG, 2004)

CO2 (except for Cyanides), dry chemical, dry sand, alcohol-resistant foam.

LARGE FIRE PRECAUTIONS - EMERGENCY RESPONSE GUIDEBOOK, GUIDE 157 (ERG, 2004)

Water spray, fog or alcohol-resistant foam.
Move containers from fire area if you can do it without risk.
Use water spray or fog; do not use straight streams.
Dike fire control water for later disposal; do not scatter the material.

TANK OR CAR/TRAILER LOAD FIRE PRECAUTIONS - EMERGENCY RESPONSE GUIDEBOOK, GUIDE 157 (ERG, 2004)

Fight fire from maximum distance or use unmanned hose holders or monitor nozzles.
Do not get water inside containers.
Cool containers with flooding quantities of water until well after fire is out.
Withdraw immediately in case of rising sound from venting safety devices or discoloration of tank.
ALWAYS stay away from tanks engulfed in fire.

NFPA Extinguishing Methods for CAS594-42-3 (NFPA, 2002):

Not Listed

COMBUSTION TOXICITY

When heated to decomposition, perchloromethyl mercaptan emits very toxic fumes of chlorides and oxides of sulfur (Sax & Lewis, 1989).
Toxic gases and vapors, such as carbon tetrachloride, hydrogen sulfide, sulfur dioxide, and carbon monoxide, may be released in fires involving perchloromethyl mercaptan (HSDB , 1992).

DUST/VAPOR HAZARD

When heated to decomposition, perchloromethyl mercaptan emits very toxic fumes of chlorides and oxides of sulfur (Sax & Lewis, 1989).

Toxic gases and vapors, such as carbon tetrachloride, hydrogen sulfide, sulfur dioxide, and carbon monoxide, may be released in fires involving perchloromethyl mercaptan (HSDB , 1992).

REACTIVITY HAZARD

When heated to decomposition, perchloromethyl mercaptan emits very toxic fumes of chlorides and oxides of sulfur (Lewis, 1992).

Toxic gases and vapors, such as carbon tetrachloride, hydrogen sulfide, sulfur dioxide, and carbon monoxide, may be released in fires involving perchloromethyl mercaptan (HSDB , 1995).

Perchloromethyl mercaptan is corrosive to most metals (HSDB , 1995).

It reacts with iron or steel, evolving carbon tetrachloride (HSDB , 1995).

Perchloromethyl mercaptan is slowly decomposed by moist air, and reacts with oxidizing agents, reducing agents, chlorine, etc (Lewis, 1987).

Perchloromethyl mercaptan is incompatible with alkalies, amines, hot iron, and water (NIOSH, 1995).

When hot, perchloromethyl mercaptan reacts with water to yield carbon dioxide, hydrochloric acid, and sulfur (CHRIS , 1995).

Perchloromethyl mercaptan is not flammable, but will support combustion (ACGIH, 1991).

EVACUATION PROCEDURES

SUMMARY

Initial Isolation and Protective Action Distances (ERG, 2004)

Data presented from the Emergency Response Guidebook Table of Initial Isolation and Protective Action Distances are for use when a spill has occurred and there is no fire. If there is a fire, or if a fire is involved, evacuation information presented under FIRE - PUBLIC SAFETY EVACUATION DISTANCES should be used.
Generally, a small spill is one that involves a single, small package such as a drum containing up to approximately 200 liters, a small cylinder, or a small leak from a large package. A large spill is one that involves a spill from a large package, or multiple spills from many small packages.
Suggested distances to protect from vapors of toxic-by-inhalation and/or water-reactive materials during the first 30 minutes following the spill.

DOT ID No. 1670 - Perchloromethyl mercaptan

SMALL SPILLS

First isolate in all directions: 30 meters (100 feet).
Note wind direction.
Then protect persons downwind:

during the DAY for: 0.2 kilometers (0.1 miles); or
during the NIGHT for: 0.2 kilometers (0.2 miles).

LARGE SPILLS

First isolate in all directions: 60 meters (200 feet).
Note wind direction.
Then protect persons downwind:

during the DAY for: 0.7 kilometers (0.4 miles); or
during the NIGHT for: 1.2 kilometers (0.8 miles).

SPILL - PUBLIC SAFETY EVACUATION DISTANCES - EMERGENCY RESPONSE GUIDEBOOK, GUIDE 157 (ERG, 2004)

Increase, in the downwind direction, as necessary, the isolation distance of at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids in all directions.

FIRE - PUBLIC SAFETY EVACUATION DISTANCES - EMERGENCY RESPONSE GUIDEBOOK, GUIDE 157 (ERG, 2004)

If tank, rail car or tank truck is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions.

PUBLIC SAFETY MEASURES - EMERGENCY RESPONSE GUIDEBOOK, GUIDE 157 (ERG, 2004)

CALL Emergency Response Telephone Number on Shipping Paper first. If Shipping Paper not available or no answer, refer to appropriate telephone number:

MEXICO:

SETIQ:

01-800-00-214-00 in the Mexican Republic;
For calls originating in Mexico City and the Metropolitan Area: 5559-1588;
For calls originating elsewhere, call: 011-52-555-559-1588.

CENACOM:

01-800-00-413-00 in the Mexican Republic;
For calls originating in Mexico City and the Metropolitan Area: 5550-1496, 5550-1552, 5550-1485, or 5550-4885;
For calls originating elsewhere, call: 011-52-555-550-1496, or 011-52-555-550-1552; 011-52-555-550-1485, or 011-52-555-550-4885.

ARGENTINA:

CIQUIME:

0-800-222-2933 in the Republic of Argentina;
For calls originating elsewhere, call: +54-11-4613-1100.

BRAZIL:

PRÓ-QUÍMICA:

0-800-118270 (Toll-free in Brazil);
For calls originating elsewhere, call: +55-11-232-1144 (Collect calls are accepted).

COLUMBIA:

CISPROQUIM:

01-800-091-6012 in Colombia;
For calls originating in Bogotá, Colombia, call: 288-6012;
For calls originating elsewhere, call: 011-57-1-288-6012.

CANADA:

CANUTEC:

613-996-6666 (Collect calls are accepted);
*666 cellular (in Canada only).

UNITED STATES:

CHEMTREC®:

1-800-424-9300 (Toll-free in the U.S., Canada, and the U.S. Virgin Islands);
703-527-3887 for calls originating elsewhere (Collect calls are accepted).

CHEM-TEL, INC.:

1-800-255-3924 (Toll-free in the U.S., Canada, and the U.S. Virgin Islands);
813-248-0585 for calls originating elsewhere (Collect calls are accepted).

INFOTRAC:

1-800-535-5053 (Toll-free in the U.S., Canada, and the U.S. Virgin Islands);
352-323-3500 for calls originating elsewhere (Collect calls are accepted).

3E COMPANY:

1-800-451-8346 (Toll-free in the U.S., Canada, and the U.S. Virgin Islands);
760-602-8703 for calls originating elsewhere (Collect calls are accepted).

NATIONAL RESPONSE CENTER (NRC):

1-800-424-8802 - (24 hours) (Toll-free in the U.S., Canada, and the U.S. Virgin Islands);
202-267-2675 for calls in the District of Columbia.

MILITARY SHIPMENTS:

703-697-0218 - Explosives/ammunition incidents (Collect calls are accepted);
1-800-851-8061 - All other dangerous goods incidents.

NATIONWIDE POISON CONTROL CENTER (United States only):

1-800-222-1222 (Toll-free in the U.S.).

For additional details see the section entitled "WHO TO CALL FOR ASSISTANCE" under the ERG Instructions.
As an immediate precautionary measure, isolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids.
Keep unauthorized personnel away.
Stay upwind.
Keep out of low areas.
Ventilate enclosed areas.

AIHA ERPG Values for CAS594-42-3 (AIHA, 2006):

Not Listed

DOE TEEL Values for CAS594-42-3 (U.S. Department of Energy, Office of Emergency Management, 2010):

Listed as Perchloromethyl mercaptan
TEEL-0 (units = ppm): 0.013
TEEL-1 (units = ppm): 0.013
TEEL-2 (units = ppm): 0.3
TEEL-3 (units = ppm): 0.9
Definitions:

TEEL-0: The threshold concentration below which most people will experience no adverse health effects.
TEEL-1: The airborne concentration (expressed as ppm [parts per million] or mg/m(3) [milligrams per cubic meter]) of a substance above which it is predicted that the general population, including susceptible individuals, could experience notable discomfort, irritation, or certain asymptomatic, nonsensory effects. However, these effects are not disabling and are transient and reversible upon cessation of exposure.
TEEL-2: The airborne concentration (expressed as ppm or mg/m(3)) of a substance above which it is predicted that the general population, including susceptible individuals, could experience irreversible or other serious, long-lasting, adverse health effects or an impaired ability to escape.
TEEL-3: The airborne concentration (expressed as ppm or mg/m(3)) of a substance above which it is predicted that the general population, including susceptible individuals, could experience life-threatening adverse health effects or death.

AEGL Values for CAS594-42-3 (National Research Council, 2010; National Research Council, 2009; National Research Council, 2008; National Research Council, 2007; NRC, 2001; NRC, 2002; NRC, 2003; NRC, 2004; NRC, 2004; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2006; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2007; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2005; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2005; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2007; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2006; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2006; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2006; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2006; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2006; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2006; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2006; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2006; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2006; United States Environmental Protection Agency Office of Pollution Prevention and Toxics, 2006; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2006; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2007; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2007; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2007; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2007; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2007; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2009; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2009; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2009; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2009; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2009; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2009; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2009; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2009; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2009; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2009; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2009; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2009; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2009; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2007; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2006; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2006; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2006; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2007; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2007; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2007; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2007; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2007; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2005; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2005; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2005; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2005; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2005; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2005; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2005; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2005; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2007; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2005; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2006; 62 FR 58840, 1997; 65 FR 14186, 2000; 65 FR 39264, 2000; 65 FR 77866, 2000; 66 FR 21940, 2001; 67 FR 7164, 2002; 68 FR 42710, 2003; 69 FR 54144, 2004):

Listed as: Perchloromethyl mercaptan
Proposed Value:

AEGL-1

10 min exposure:

ppm: 0.018 ppm
mg/m3: 0.14 mg/m(3)

30 min exposure:

ppm: 0.018 ppm
mg/m3: 0.14 mg/m(3)

1 hr exposure:

ppm: 0.014 ppm
mg/m3: 0.11 mg/m(3)

4 hr exposure:

ppm: 0.009 ppm
mg/m3: 0.068 mg/m(3)

8 hr exposure:

ppm: 0.006 ppm
mg/m3: 0.046 mg/m(3)

Definitions:

AEGL-1 is the airborne concentration of a substance above which it is predicted that the general population, including susceptible individuals, could experience notable discomfort, irritation, or certain asymptomatic non-sensory effects. However, the effects are not disabling, are transient, and are reversible upon cessation of exposure.

Listed as: Perchloromethyl mercaptan
Proposed Value:

AEGL-2

10 min exposure:

ppm: 0.044 ppm
mg/m3: 0.33 mg/m(3)

30 min exposure:

ppm: 0.044 ppm
mg/m3: 0.33 mg/m(3)

1 hr exposure:

ppm: 0.035 ppm
mg/m3: 0.27 mg/m(3)

4 hr exposure:

ppm: 0.022 ppm
mg/m3: 0.17 mg/m(3)

8 hr exposure:

ppm: 0.015 ppm
mg/m3: 0.11 mg/m(3)

Definitions:

AEGL-2 is the airborne concentration of a substance above which it is predicted that the general population, including susceptible individuals, could experience irreversible or other serious, long-lasting adverse health effects or an impaired ability to escape.

Listed as: Perchloromethyl mercaptan
Proposed Value:

AEGL-3

10 min exposure:

ppm: 0.54 ppm
mg/m3: 4.1 mg/m(3)

30 min exposure:

ppm: 0.38 ppm
mg/m3: 2.9 mg/m(3)

1 hr exposure:

ppm: 0.3 ppm
mg/m3: 2.3 mg/m(3)

4 hr exposure:

ppm: 0.075 ppm
mg/m3: 0.57 mg/m(3)

8 hr exposure:

ppm: 0.038 ppm
mg/m3: 0.29 mg/m(3)

Definitions:

AEGL-3 is the airborne concentration of a substance above which it is predicted that the general population, including susceptible individuals, could experience life-threatening health effects or death.

NIOSH IDLH Values for CAS594-42-3 (National Institute for Occupational Safety and Health, 2007):

IDLH: 10 ppm
Note(s): Not Listed

CONTAINMENT/WASTE TREATMENT OPTIONS

SUMMARY

SPILL OR LEAK PRECAUTIONS - EMERGENCY RESPONSE GUIDEBOOK, GUIDE 157 (ERG, 2004)
- ELIMINATE all ignition sources (no smoking, flares, sparks or flames in immediate area).
- All equipment used when handling the product must be grounded.
- Do not touch damaged containers or spilled material unless wearing appropriate protective clothing.
- Stop leak if you can do it without risk.
- A vapor suppressing foam may be used to reduce vapors.
- DO NOT GET WATER INSIDE CONTAINERS.
- Use water spray to reduce vapors or divert vapor cloud drift. Avoid allowing water runoff to contact spilled material.
- Prevent entry into waterways, sewers, basements or confined areas.
RECOMMENDED PROTECTIVE CLOTHING - EMERGENCY RESPONSE GUIDEBOOK, GUIDE 157 (ERG, 2004)
- Wear positive pressure self-contained breathing apparatus (SCBA).
- Wear chemical protective clothing that is specifically recommended by the manufacturer. It may provide little or no thermal protection.
- Structural firefighters' protective clothing provides limited protection in fire situations ONLY; it is not effective in spill situations where direct contact with the substance is possible.
No information on disposal guidelines for perchloromethyl mercaptan was found in available references at the time of this review.

SMALL LEAK/SPILL

SMALL SPILL PRECAUTIONS - EMERGENCY RESPONSE GUIDEBOOK, GUIDE 157 (ERG, 2004)
- Cover with DRY earth, DRY sand, or other non-combustible material followed with plastic sheet to minimize spreading or contact with rain.
- Use clean non-sparking tools to collect material and place it into loosely covered plastic containers for later disposal.

-ENVIRONMENTAL HAZARD MANAGEMENT

POLLUTION HAZARD

Perchloromethyl mercaptan may be released to the environment as a result of its manufacture and use as an intermediate, principally in the production of fungicides, including captan and folpet (HSDB , 1992).

ENVIRONMENTAL FATE AND KINETICS

OTHER

OTHER
- TERRESTRIAL FATE: If perchloromethyl mercaptan is released to soil, it will be expected to slowly hydrolyze. No data were located and no estimations could be made concerning biodegradation in, adsorption to, or volatilization from, soil. Based upon a measured vapor pressure of 3 mmHg at 20 degrees C, volatilization from dry near-surface soil or surfaces may be significant processes (HSDB , 1992).
- AQUATIC FATE: If perchloromethyl mercaptan is released to water, it will be expected to slowly hydrolyze. No data were located and no estimations could be made concerning bioconcentration, biodegradation, volatilization, and adsorption to sediment and suspended solids (HSDB , 1992).
- ATMOSPHERIC FATE: If perchloromethyl mercaptan is released to the atmosphere, it will be expected to exist almost entirely in the vapor phase based upon a reported vapor pressure of 3 mmHg at 20 degrees C. It will be susceptible to photo-oxidation via vapor phase reaction with photochemically produced hydroxyl radicals. An atmospheric half-life of 8 days at an atmospheric concentration of 5 x 10(5) hydroxyl radicals per cubic centimeter has been calculated for this process based upon an estimated rate constant (HSDB , 1992).

ENVIRONMENTAL TOXICITY

Effect of low concentrations on aquatic life is unknown. May be dangerous if it enters water intakes (CHRIS , 1992).

-PHYSICAL/CHEMICAL PROPERTIES

MOLECULAR WEIGHT

185.87 (Lewis, 1992)

185.89 (ACGIH, 1986)

DESCRIPTION/PHYSICAL STATE

Perchloromethyl mercaptan is a yellow to orange-red, oily liquid; it is yellow in water (AAR, 1992; ACGIH, 1991; HSDB , 1995; OHM/TADS , 1995; Hathaway et al, 1991; Sax & Lewis, 1987; Lewis, 1992).

It has an odor which has been described as acrid, disagreeable, strong, unbearable and unpleasant (ACGIH, 1991; HSDB , 1995) NIOSH, 1995; Lewis, 1987; (Lewis, 1992).

Perchloromethyl mercaptan slowly hydrolyzes to form hydrochloric acid (HSDB , 1995). It would therefore be acidic.

VAPOR PRESSURE

3 mmHg (at 20 degrees C) (HSDB , 1995)

65 torr (at 20 degrees C) (ACGIH, 1986)

DENSITY

STANDARD TEMPERATURE AND PRESSURE

(0 degrees C; 32 degrees F and 760 mmHg)
1.722 g/cm(3) (Sax & Lewis, 1987)

OTHER TEMPERATURE AND/OR PRESSURE

1.7 g/cm(3) (at 20 degrees C) (HSDB , 1995; Lewis, 1992)
1.6947 g/cm(3) (at 20 degrees C) (ACGIH, 1986)
1.706 g/cm(3) (at 11 degrees C) (CHRIS , 1985)

FREEZING/MELTING POINT

MELTING POINT

No information found at the time of this review.

BOILING POINT

147-148 degrees C (at 760 mmHg) (HSDB , 1995)

148-149 degrees C (decomposes) (HSDB , 1995; ACGIH, 1991; Sax & Lewis, 1987)

51 degrees C (at 25 mmHg) (HSDB , 1995)

SOLUBILITY

IN WATER

Perchloromethyl mercaptan is insoluble in water (ACGIH, 1991; Sax & Lewis, 1987).

IN ORGANIC SOLVENTS

Perchloromethyl mercaptan is soluble in ether (ACGIH, 1991; Sax & Lewis, 1987).

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PERCHLOROMETHYL MERCAPTAN

Classification | Information to evaluate chemical incidents

Information to evaluate chemical incidents

Information to evaluate chemical incidents

Information to evaluate chemical incidents