PARIS GREEN

Paris Green was extensively used in the past as an insecticide, wood preservative, and pigment (particularly for marine anti-fouling paints) and has also been used as an anthelmintic and larvicide (EPA, 1985; Sax & Lewis, 1987; HSDB , 1993). It is not currently used in the USA (Morgan, 1989).

FORMS

Paris Green is an inorganic trivalent arsenic compound which also contains copper (Morgan, 1989). It is an odorless, emerald green-colored, crystalline powder (Budavari, 1989; Sax & Lewis, 1987; EPA, 1985). It is soluble in ammonium hydroxide and insoluble in cold water and alcohol (HSDB , 1993).
The ACGIH has established a Biological Exposure Index (BEI) for arsenic. Refer to the BIOMONITORING section for more information.
This review is based on the effects of arsenic and its inorganic compounds in general. Effects attributed specifically to Paris Green are identified. The toxicology of arsenic and its compounds has been reviewed (Friberg et al, 1986).

-CLINICAL EFFECTS

GENERAL CLINICAL EFFECTS

Paris Green is an inorganic trivalent arsenic compound which also contains copper. It is an emerald green colored, crystalline powder. Although some absorption may occur from dermal contact or inhalation, most poisonings result from ingestion. Upper respiratory tract irritation may result from inhalation exposure.

Direct contact may produce conjunctival irritation or a characteristic dermatitis. Other skin findings may be melanosis, hyperkeratosis and hyperhidrosis. Hair loss and trophic nail changes may also occur with chronic exposure.

Systemic Paris Green poisoning is primarily due to the arsenic content, and is not different from any other arsenic poisoning. Chronic copper poisoning from Paris Green exposure is essentially unknown in humans. It is advisable to treat all arsenic compounds as highly toxic.

Multiple keratoses, chronic lymphatic leukemia and macular degeneration have been tied to occupational exposure.

Acute arsenic ingestion generally produces symptoms within 30 to 60 minutes, but onset may be delayed for several hours if ingested with food. A metallic or garlic taste, vomiting, abdominal pain, dysphagia, and profuse watery (rice-water-like) and sometimes bloody diarrhea may occur. Dehydration, intense thirst, and fluid-electrolyte disturbances are common. Hypovolemia from capillary leaking ("third spacing" of fluids) is a common early sign.

Systemic arsenic poisoning from occupational exposure is uncommon. Arsenic workers have developed a hoarse voice; nasal irritation and possible perforation of the nasal septum; irritation of eyes, skin, and mucous membranes; and, rarely, cirrhosis of the liver. Nausea and vomiting are infrequent. Painful ulceration of the wrist and scrotal skin, lips, and nostrils may develop with dust exposure.

The primary target organs initially are the gastrointestinal tract, heart, brain, and kidneys. Seizures and pulkonary edema can result from exposure. Eventually, the skin, bone marrow, and peripheral nervous system may be significantly damaged. The peripheral neuropathy appears similar regardless of the route of exposure.

POTENTIAL HEALTH HAZARDS - EMERGENCY RESPONSE GUIDEBOOK, GUIDE 151 (ERG, 2004)

Highly toxic, may be fatal if inhaled, swallowed or absorbed through skin.
Avoid any skin contact.
Effects of contact or inhalation may be delayed.
Fire may produce irritating, corrosive and/or toxic gases.
Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution.

ACUTE CLINICAL EFFECTS

From its acute oral LD50 of 22 mg/kg in rats (RTECS , 1993), Paris Green is a HIGHLY TOXIC SUBSTANCE. Although some absorption may occur from dermal contact or inhalation, most Paris Green poisonings result from ingestion (EPA, 1985). It is an eye, skin, and respiratory tract irritant (EPA, 1985; Grant, 1986; OHM/TADS , 1993). Systemic Paris Green poisoning is primarily due to the arsenic content, and signs and symptoms are not different from those caused by any other arsenic poisoning (Budavari, 1989; HSDB , 1993; OHM/TADS , 1993).

Acute arsenic ingestion generally produces signs and symptoms within 30 to 60 minutes, but onset may be delayed for several hours if ingested with food (Morgan, 1989; Sittig, 1985). A metallic or garlic taste and garlic-like odor of the breath, vomiting, abdominal pain, dysphagia, and profuse watery (ricewater-like) and sometimes bloody diarrhea may occur (Sittig, 1985; Finkel, 1983; EPA, 1988).

Dehydration, intense thirst, and fluid-electrolyte disturbances are common (Morgan, 1989). Hypovolemia from capillary leaking ("third spacing" of fluids) is a common early sign (Morgan, 1989; EPA, 1988; HSDB , 1993). Cardiac arrhythmias may occur, but may be secondary to electrolyte imbalance (Peterson & Rumack, 1977; Goldsmith, 1980; St Peter et al, 1970; Sittig, 1985).

The primary initial target organs are the gastrointestinal tract, heart, brain, and kidneys (Sittig, 1985; Morgan, 1989; Finkel, 1983; HSDB , 1993). Eventually, the skin, bone marrow, and peripheral nervous system may be significantly damaged (Finkel, 1983; Morgan, 1989; Sittig, 1985; HSDB , 1993). Hemolysis, pancytopenia, and anemia may occur after acute arsenic poisoning (Kyle & Pease, 1965; Kjeldsberg & Ward, 1972).

MEE'S LINES may be seen after acute exposure. Mee's lines commonly take 5 weeks to appear above the cuticle and advance 1 mm per week afterwards, allowing an approximation of the time of acute exposure (Heyman et al, 1956).

Permanent encephalopathy may ensue from acute exposure to arsenic compounds. This encephalopathy can result in atrophy of the cortex one to six months after exposure (Fincher & Koerker, 1987), causing loss of many higher brain functions.

Peripheral neuropathy (both sensory and motor) can appear in a similar pattern regardless of the route arsenic exposure (Finkel, 1983). It commonly begins 1 to 3 weeks following exposure (Le Quesne & McLeod, 1977; Heyman et al, 1956), usually as paresthesias of the soles of the feet and hands, progressing proximally over the next few days (Heyman et al, 1956).

Severe muscle weakness and wasting then develop, causing severe disability (Le Quesne & McLeod, 1977). It may initially be confused with Guillain-Barre' syndrome (Donofrio et al, 1987). Paresthesias may be painful and are frequently described as severe burning pain in a "stocking and glove" distribution.

Physical findings of arsenic peripheral neuropathy include prominently decreased sensation to touch, pinprick, and temperature, frequently in a stocking and glove distribution (Heyman et al, 1956). Loss of vibration sense is also common. Profound muscle weakness and wasting, distal more than proximal, is also seen (Donofrio et al, 1987; Heyman et al, 1956). Wrist drop, foot drop, and muscle fasciculations may also occur in patients with arsenic poisoning (Heyman et al, 1956).

Arsenic is a general cellular poison. It inhibits enzymes required for cellular respiration and depletes cellular energy stores, leading to cell death (Schoolmeester & White, 1980).

CHRONIC CLINICAL EFFECTS

Systemic absorption of as little as 3 to 4 mg of arsenic per day can cause chronic poisoning (HSDB , 1993). Trivalent arsenicals, such as those found in Paris Green, are eliminated less rapidly than pentavalent compounds and can thus cause CUMULATIVE TOXICITY (HSDB , 1993). Chronic COPPER poisoning from Paris Green exposure is essentially unknown in humans (OHM/TADS , 1993).

Effects of chronic arsenic poisoning include hyperpigmentation of the skin (especially on the palms of the hands and soles of the feet), BLACKFOOT DISEASE, anemia, peripheral neuropathies, cirrhosis of the liver, hair loss, and nail changes (ILO, 1983) Finkel, 1983).

Workers chronically exposed to arsenic by inhalation and dermal contact have mainly developed a hoarse voice, nasal irritation, perforation of the nasal septum, irritation of eyes, skin, and mucous membranes, and rarely, cirrhosis of the liver (ACGIH, 1986; (Finkel, 1983; Sittig, 1985; Proctor et al, 1988; Clayton & Clayton, 1981). Nausea and vomiting are infrequent complaints among chronically-exposed arsenic workers (Clayton & Clayton, 1981). Painful ulceration of the wrist and scrotal skin, lips, and nostrils may develop with chronic arsenic dust exposure (Finkel, 1983; Sittig, 1985).

Dermatitis due to Paris Green exposure has a dry, scaly appearance and can result in a brownish skin pigmentation (Grant, 1986), commonly found on the scrotum, inguinal area, and nasolabial folds (HSDB , 1993). Lesions may begin with erythema and progress to eczema with weeping, followed by healing with a dark pigmentation (HSDB , 1993). These skin lesions may vary from local inflammation, with or without the presence of ulcers, to thickened, hyperkeratotic and pigmented lesions (Finkel, 1983). Malignant transformation may occur in some of these skin lesions (Finkel, 1983).

Chronic arsenic poisoning can result in alopecia and liver enlargement in addition to the signs and symptoms mentioned in the ACUTE EXPOSURE section (Finkel, 1983). Aplastic anemia has been described after chronic arsenic exposure (Kjeldsberg & Ward, 1972).

Arsenic compounds can cause cancer in humans. (Refer to the CARCINOGENIC EFFECTS section below for more information.)

-MEDICAL TREATMENT

LIFE SUPPORT

Support respiratory and cardiovascular function.

SUMMARY

FIRST AID - EMERGENCY RESPONSE GUIDEBOOK, GUIDE 151 (ERG, 2004)

Move victim to fresh air.
Call 911 or emergency medical service.
Give artificial respiration if victim is not breathing.
Do not use mouth-to-mouth method if victim ingested or inhaled the substance;give artificial respiration with the aid of a pocket mask equipped with a one-way valve or other proper respiratory medical device.
Administer oxygen if breathing is difficult.
Remove and isolate contaminated clothing and shoes.
In case of contact with substance, immediately flush skin or eyes with running water for at least 20 minutes.
For minor skin contact, avoid spreading material on unaffected skin.
Keep victim warm and quiet.
Effects of exposure (inhalation, ingestion or skin contact) to substance may be delayed.
Ensure that medical personnel are aware of the material(s) involved and take precautions to protect themselves.

-RANGE OF TOXICITY

MINIMUM LETHAL EXPOSURE

ACUTE

One milligram/kilogram of ingested arsenic may be lethal in a child (Woody & Kometani, 1948; HSDB , 2000).
As little as 20 milligrams of arsenic may produce life-threatening toxicity (Zaloga et al, 1970; Schoolmeester & White, 1980; Hutton & Christians, 1983).
An oral dose of 120 mg of arsenic trioxide may be fatal (Finkel, 1983).

CASE REPORTS

Between 1966 and 1979, 61 cases of accidental sodium arsenite poisoning, including 11 patients who were hospitalized and 24 fatal cases in adults and children, were reported to the EPA's Pesticide Incident Monitoring System (PIMS) (EPA, 1988).

MAXIMUM TOLERATED EXPOSURE

GENERAL/SUMMARY

AVERAGE HUMAN ARSENIC INTAKE - 250 to 330 micrograms/day (in food and water) (Gilman et al, 1985; Baselt & Cravey, 1989)

ACUTE

Estimates of acute oral toxic doses of various arsenic compounds range from 1 milligram to 10 grams.
Arsenic trioxide in a solubilized form becomes sodium arsenite, which is more toxic than in an unsolubilized form. 200 milligrams of arsenic trioxide ingested acutely by an adult may be lethal (Baselt & Cravey, 1989; Baselt, 1988).
Trivalent arsenic (arsenite) is more toxic in animals than the pentavalent form (arsenate) (Morgan, 1989). However, significant toxicity may occur with large amounts of pentavalent salts in humans. Pentavalent arsenic may be converted in vivo to trivalent arsenic.

CASE REPORTS

INFANT

Acute ingestion of 9 to 14 milligrams of arsenic trioxide by a 16-month-old child produced classic GI signs and symptoms of arsenic poisoning (Watson et al, 1981).

ADULT

A 30-year-old man survived an ingestion of 6 ounces of "Blue Ball Rat Killer" containing 1.5% arsenous oxide (2,150 milligrams metallic arsenic per 6 ounces) with aggressive therapy (fluid resuscitation, chelation, and hemodialysis) (Fesmire et al, 1988).

OCCUPATIONAL

OCCUPATIONAL EXPOSURES (ACGIH, 1986) -

No definite evidence of intoxication was noted in a pharmaceutical plant with an average arsenic air concentration of 0.2 mg/m(3) (ACGIH, 1986).
An increased incidence of cancer was reported in factories with airborne arsenic concentrations of 0.002 to 0.65 mg/m(3) in "light exposure areas" and 1.47 to 1.56 mg/m(3) in "medium and high exposure areas" (ACGIH, 1986).

Carcinogenicity Ratings for CAS12002-03-8 :

ACGIH (American Conference of Governmental Industrial Hygienists, 2010): Not Listed
EPA (U.S. Environmental Protection Agency, 2011): Not Listed
IARC (International Agency for Research on Cancer (IARC), 2016; International Agency for Research on Cancer, 2015; IARC Working Group on the Evaluation of Carcinogenic Risks to Humans, 2010; IARC Working Group on the Evaluation of Carcinogenic Risks to Humans, 2010a; IARC Working Group on the Evaluation of Carcinogenic Risks to Humans, 2008; IARC Working Group on the Evaluation of Carcinogenic Risks to Humans, 2007; IARC Working Group on the Evaluation of Carcinogenic Risks to Humans, 2006; IARC, 2004): Not Listed
NIOSH (National Institute for Occupational Safety and Health, 2007): Not Listed
MAK (DFG, 2002): Not Listed
NTP (U.S. Department of Health and Human Services, Public Health Service, National Toxicology Project ): Not Listed

TOXICITY AND RISK ASSESSMENT VALUES

EPA IRIS

EPA Risk Assessment Values for CAS12002-03-8 (U.S. Environmental Protection Agency, 2011):

Not Listed

TOXICITY VALUES

References: RTECS, 2000 Lewis, 1996; Budavari, 1996 OHM/TADS, 2000
- LD50- (ORAL)RABBIT:
- LD50- (ORAL)RAT:
- LD50- (SKIN)RAT:

-STANDARDS AND LABELS

WORKPLACE STANDARDS

ACGIH TLV Values for CAS12002-03-8 (American Conference of Governmental Industrial Hygienists, 2010):

Not Listed

AIHA WEEL Values for CAS12002-03-8 (AIHA, 2006):

Not Listed

NIOSH REL and IDLH Values for CAS12002-03-8 (National Institute for Occupational Safety and Health, 2007):

Not Listed

OSHA PEL Values for CAS12002-03-8 (U.S. Occupational Safety, and Health Administration (OSHA), 2010):

Not Listed

OSHA List of Highly Hazardous Chemicals, Toxics, and Reactives for CAS12002-03-8 (U.S. Occupational Safety and Health Administration, 2010):

Not Listed

ENVIRONMENTAL STANDARDS

EPA CERCLA, Hazardous Substances and Reportable Quantities for CAS12002-03-8 (U.S. Environmental Protection Agency, 2010):

Listed as: Cupric acetoarsenite
Final Reportable Quantity, in pounds (kilograms):

1 (0.454)

Additional Information:

EPA CERCLA, Hazardous Substances and Reportable Quantities, Radionuclides for CAS12002-03-8 (U.S. Environmental Protection Agency, 2010):

Not Listed

EPA RCRA Hazardous Waste Number for CAS12002-03-8 (U.S. Environmental Protection Agency, 2010b):

Not Listed
Editor's Note: The D, F, and K series waste numbers and Appendix VIII to Part 261 -- Hazardous Constituents were not included. Please refer to 40 CFR Part 261.

EPA SARA Title III, Extremely Hazardous Substance List for CAS12002-03-8 (U.S. Environmental Protection Agency, 2010):

Listed as: Paris Green
Reportable Quantity, in pounds: 1

Only the statutory or final RQ is shown. For more information, see 40 CFR table 302.4.

Threshold Planning Quantity, in pounds:

500/10,000
Amount necessary to be covered by this standard. See 40 CFR 355.30.

Note(s): Not Listed

EPA SARA Title III, Community Right-to-Know for CAS12002-03-8 (40 CFR 372.65, 2006; 40 CFR 372.28, 2006):

Not Listed

DOT List of Marine Pollutants for CAS12002-03-8 (49 CFR 172.101 - App. B, 2005):

Listed as Copper acetoarsenite
Severe Marine Pollutant: No

EPA TSCA Inventory for CAS12002-03-8 (EPA, 2005):

Not Listed

SHIPPING REGULATIONS

SURFACE

DOT -- Table of Hazardous Materials and Special Provisions for UN/NA Number 1585 (49 CFR 172.101, 2005):

Hazardous materials descriptions and proper shipping name: Copper acetoarsenite

Symbol(s): Not Listed
Hazard class or Division: 6.1

6.1: Poisonous materials. See 49 CFR section 173.132 for definitions.

Identification Number: UN1585
Packing Group: II

II: Packing Group II - indicates the degree of danger presented by the material is medium.

Label(s) required (if not excepted): 6.1

6.1: Poison Inhalation Hazard (inhalation hazard, Zone A or B) or Poison (other than inhalation hazard, Zone A or B; the packing group for a material is indicated in column 5 of the table.).

Special Provisions: IB8, IP2, IP4, T3, TP33

IB8: Authorized IBCs: Metal (11A, 11B, 11N, 21A, 21B, 21N, 31A, 31B and 31N); Rigid plastics (11H1, 11H2, 21H1, 21H2, 31H1 and 31H2); Composite (11HZ1, 11HZ2, 21HZ1, 21HZ2, 31HZ1 and 31HZ2); Fiberboard (11G); Wooden (11C, 11D and 11F); Flexible (13H1, 13H2, 13H3, 13H4, 13H5, 13L1, 13L2, 13L3, 13L4, 13M1 or 13M2).
IP2: When IBCs other than metal or rigid plastics IBCs are used, they must be offered for transportation in a closed freight container or a closed transport vehicle.
IP4: Flexible, fiberboard or wooden IBCs must be sift-proof and water-resistant or be fitted with a sift-proof and water-resistant liner.
T3: Minimum test pressure (bar): 2.65; Minimum shell thickness (in mm-reference steel) (See sxn.178.274(d)): sxn.178.274(d)(2); Pressure-relief requirements (See sxn.178.275(g)): Normal; Bottom opening requirements (See sxn.178.275(d)): sxn.178.275(d)(2).
TP33: The portable tank instruction assigned for this substance applies for granular and powdered solids and for solids which are filled and discharged at temperatures above their melting point which are cooled and transported as a solid mass. Solid substances transported or offered for transport above their melting point are authorized for transportation in portable tanks conforming to the provisions of portable tank instruction T4 for solid substances of packing group III or T7 for solid substances of packing group II, unless a tank with more stringent requirements for minimum shell thickness, maximum allowable working pressure, pressure-relief devices or bottom outlets are assigned in which case the more stringent tank instruction and special provisions shall apply. Filling limits must be in accordance with portable tank special provision TP3. Solids meeting the defnintion of an elevated temperature material must be transported in accordance with the applicable requirements of this subchapter.

Packaging Authorizations (refer to 49 CFR 173.***):

Exceptions: 153
Non-bulk packaging: 212
Bulk packaging: 242

Quantity Limitations:

Passenger aircraft or railcar: 25 kg
Cargo aircraft only: 100 kg

Vessel Stowage Requirements:

Vessel stowage location: A

A: The material may be stowed "on deck" or "under deck" on a cargo vessel and on a passenger vessel.

Vessel stowage other: Not Listed

ICAO International Shipping Name for UN1585 (ICAO, 2002):

Proper Shipping Name: Copper acetoarsenite
UN Number: 1585

LABELS

NFPA

NFPA Hazard Ratings for CAS12002-03-8 (NFPA, 2002):

Not Listed

-PERSONAL PROTECTION

SUMMARY

RECOMMENDED PROTECTIVE CLOTHING - EMERGENCY RESPONSE GUIDEBOOK, GUIDE 151 (ERG, 2004)

Wear positive pressure self-contained breathing apparatus (SCBA).
Wear chemical protective clothing that is specifically recommended by the manufacturer. It may provide little or no thermal protection.
Structural firefighters' protective clothing provides limited protection in fire situations ONLY; it is not effective in spill situations where direct contact with the substance is possible.

PROTECTIVE CLOTHING

CHEMICAL PROTECTIVE CLOTHING. Search results for CAS 12002-03-8.

Specific recommendations and test data for this chemical were not found in the available manufacturers' product literature. A complete list of consulted manufacturers and references is presented below.

-PHYSICAL HAZARDS

FIRE HAZARD

SUMMARY

POTENTIAL FIRE OR EXPLOSION HAZARDS - EMERGENCY RESPONSE GUIDEBOOK, GUIDE 151 (ERG, 2004)
- Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes.
- Containers may explode when heated.
- Runoff may pollute waterways.

FLAMMABILITY CLASSIFICATION

NFPA Flammability Rating for CAS12002-03-8 (NFPA, 2002):

Not Listed

FIRE CONTROL/EXTINGUISHING AGENTS

SMALL FIRE PRECAUTIONS - EMERGENCY RESPONSE GUIDEBOOK, GUIDE 151 (ERG, 2004)

Dry chemical, CO2 or water spray.

LARGE FIRE PRECAUTIONS - EMERGENCY RESPONSE GUIDEBOOK, GUIDE 151 (ERG, 2004)

Water spray, fog or regular foam.
Move containers from fire area if you can do it without risk.
Dike fire control water for later disposal; do not scatter the material.
Use water spray or fog; do not use straight streams.

TANK OR CAR/TRAILER LOAD FIRE PRECAUTIONS - EMERGENCY RESPONSE GUIDEBOOK, GUIDE 151 (ERG, 2004)

Fight fire from maximum distance or use unmanned hose holders or monitor nozzles.
Do not get water inside containers.
Cool containers with flooding quantities of water until well after fire is out.
Withdraw immediately in case of rising sound from venting safety devices or discoloration of tank.
ALWAYS stay away from tanks engulfed in fire.
For massive fire, use unmanned hose holders or monitor nozzles; if this is impossible, withdraw from area and let fire burn.

NFPA Extinguishing Methods for CAS12002-03-8 (NFPA, 2002):

Not Listed

REACTIVITY HAZARD

Contact with strong oxidizers may cause fire and explosion (Pohanish & Greene, 1997).

EVACUATION PROCEDURES

SUMMARY

Editor's Note: This material is not listed in the Table of Initial Isolation and Protective Action Distances.

SPILL - PUBLIC SAFETY EVACUATION DISTANCES - EMERGENCY RESPONSE GUIDEBOOK, GUIDE 151 (ERG, 2004)

Increase, in the downwind direction, as necessary, the isolation distance of at least 25 to 50 meters (80 to 160 feet) in all directions.

FIRE - PUBLIC SAFETY EVACUATION DISTANCES - EMERGENCY RESPONSE GUIDEBOOK, GUIDE 151 (ERG, 2004)

If tank, rail car or tank truck is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions.

PUBLIC SAFETY MEASURES - EMERGENCY RESPONSE GUIDEBOOK, GUIDE 151 (ERG, 2004)

CALL Emergency Response Telephone Number on Shipping Paper first. If Shipping Paper not available or no answer, refer to appropriate telephone number:

MEXICO:

SETIQ:

01-800-00-214-00 in the Mexican Republic;
For calls originating in Mexico City and the Metropolitan Area: 5559-1588;
For calls originating elsewhere, call: 011-52-555-559-1588.

CENACOM:

01-800-00-413-00 in the Mexican Republic;
For calls originating in Mexico City and the Metropolitan Area: 5550-1496, 5550-1552, 5550-1485, or 5550-4885;
For calls originating elsewhere, call: 011-52-555-550-1496, or 011-52-555-550-1552; 011-52-555-550-1485, or 011-52-555-550-4885.

ARGENTINA:

CIQUIME:

0-800-222-2933 in the Republic of Argentina;
For calls originating elsewhere, call: +54-11-4613-1100.

BRAZIL:

PRÓ-QUÍMICA:

0-800-118270 (Toll-free in Brazil);
For calls originating elsewhere, call: +55-11-232-1144 (Collect calls are accepted).

COLUMBIA:

CISPROQUIM:

01-800-091-6012 in Colombia;
For calls originating in Bogotá, Colombia, call: 288-6012;
For calls originating elsewhere, call: 011-57-1-288-6012.

CANADA:

CANUTEC:

613-996-6666 (Collect calls are accepted);
*666 cellular (in Canada only).

UNITED STATES:

CHEMTREC®:

1-800-424-9300 (Toll-free in the U.S., Canada, and the U.S. Virgin Islands);
703-527-3887 for calls originating elsewhere (Collect calls are accepted).

CHEM-TEL, INC.:

1-800-255-3924 (Toll-free in the U.S., Canada, and the U.S. Virgin Islands);
813-248-0585 for calls originating elsewhere (Collect calls are accepted).

INFOTRAC:

1-800-535-5053 (Toll-free in the U.S., Canada, and the U.S. Virgin Islands);
352-323-3500 for calls originating elsewhere (Collect calls are accepted).

3E COMPANY:

1-800-451-8346 (Toll-free in the U.S., Canada, and the U.S. Virgin Islands);
760-602-8703 for calls originating elsewhere (Collect calls are accepted).

NATIONAL RESPONSE CENTER (NRC):

1-800-424-8802 - (24 hours) (Toll-free in the U.S., Canada, and the U.S. Virgin Islands);
202-267-2675 for calls in the District of Columbia.

MILITARY SHIPMENTS:

703-697-0218 - Explosives/ammunition incidents (Collect calls are accepted);
1-800-851-8061 - All other dangerous goods incidents.

NATIONWIDE POISON CONTROL CENTER (United States only):

1-800-222-1222 (Toll-free in the U.S.).

For additional details see the section entitled "WHO TO CALL FOR ASSISTANCE" under the ERG Instructions.
As an immediate precautionary measure, isolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids.
Keep unauthorized personnel away.
Stay upwind.
Keep out of low areas.

AIHA ERPG Values for CAS12002-03-8 (AIHA, 2006):

Not Listed

DOE TEEL Values for CAS12002-03-8 (U.S. Department of Energy, Office of Emergency Management, 2010):

Listed as Paris Green (Cupric acetoarsenite)
TEEL-0 (units = mg/m3): 1.13
TEEL-1 (units = mg/m3): 3.38
TEEL-2 (units = mg/m3): 22
TEEL-3 (units = mg/m3): 22
Definitions:

TEEL-0: The threshold concentration below which most people will experience no adverse health effects.
TEEL-1: The airborne concentration (expressed as ppm [parts per million] or mg/m(3) [milligrams per cubic meter]) of a substance above which it is predicted that the general population, including susceptible individuals, could experience notable discomfort, irritation, or certain asymptomatic, nonsensory effects. However, these effects are not disabling and are transient and reversible upon cessation of exposure.
TEEL-2: The airborne concentration (expressed as ppm or mg/m(3)) of a substance above which it is predicted that the general population, including susceptible individuals, could experience irreversible or other serious, long-lasting, adverse health effects or an impaired ability to escape.
TEEL-3: The airborne concentration (expressed as ppm or mg/m(3)) of a substance above which it is predicted that the general population, including susceptible individuals, could experience life-threatening adverse health effects or death.

AEGL Values for CAS12002-03-8 (National Research Council, 2010; National Research Council, 2009; National Research Council, 2008; National Research Council, 2007; NRC, 2001; NRC, 2002; NRC, 2003; NRC, 2004; NRC, 2004; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2006; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2007; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2005; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2005; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2007; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2006; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2006; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2006; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2006; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2006; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2006; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2006; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2006; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2006; United States Environmental Protection Agency Office of Pollution Prevention and Toxics, 2006; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2006; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2007; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2007; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2007; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2007; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2007; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2009; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2009; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2009; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2009; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2009; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2009; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2009; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2009; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2009; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2009; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2009; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2009; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2009; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2007; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2006; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2006; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2006; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2007; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2007; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2007; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2007; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2007; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2005; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2005; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2005; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2005; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2005; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2005; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2005; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2005; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2007; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2005; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2006; 62 FR 58840, 1997; 65 FR 14186, 2000; 65 FR 39264, 2000; 65 FR 77866, 2000; 66 FR 21940, 2001; 67 FR 7164, 2002; 68 FR 42710, 2003; 69 FR 54144, 2004):

Not Listed

NIOSH IDLH Values for CAS12002-03-8 (National Institute for Occupational Safety and Health, 2007):

Not Listed

CONTAINMENT/WASTE TREATMENT OPTIONS

SUMMARY

SPILL OR LEAK PRECAUTIONS - EMERGENCY RESPONSE GUIDEBOOK, GUIDE 151 (ERG, 2004)
- Do not touch damaged containers or spilled material unless wearing appropriate protective clothing.
- Stop leak if you can do it without risk.
- Prevent entry into waterways, sewers, basements or confined areas.
- Cover with plastic sheet to prevent spreading.
- Absorb or cover with dry earth, sand or other non-combustible material and transfer to containers.
- DO NOT GET WATER INSIDE CONTAINERS.
RECOMMENDED PROTECTIVE CLOTHING - EMERGENCY RESPONSE GUIDEBOOK, GUIDE 151 (ERG, 2004)
- Wear positive pressure self-contained breathing apparatus (SCBA).
- Wear chemical protective clothing that is specifically recommended by the manufacturer. It may provide little or no thermal protection.
- Structural firefighters' protective clothing provides limited protection in fire situations ONLY; it is not effective in spill situations where direct contact with the substance is possible.

-PHYSICAL/CHEMICAL PROPERTIES

MOLECULAR WEIGHT

1013.80 (Budavari, 1996)

DESCRIPTION/PHYSICAL STATE

Paris Green is an emerald green, crystalline, ordorless powder (Budavari, 1996) HSBD, 2000).

-REFERENCES

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Information to evaluate chemical incidents

Information to evaluate chemical incidents

Information to evaluate chemical incidents