ISOOCTYL ALCOHOL

Editor's Note: This material is not listed in the Emergency Response Guidebook. Based on the material's physical and chemical properties, toxicity, or chemical group, a guide has been assigned. For additional technical information, contact one of the emergency response telephone numbers listed under Public Safety Measures.

MOLECULAR FORMULA

C8-H18-O
(CH3) 3CCH2COH (CH3)2
CH3 (CH2) 3CH (CH2CH3) CH2OH

ERG GUIDE NUMBER

131-FLAMMABLE LIQUIDS - TOXIC

SYNONYM REFERENCE

(CHRIS , 1996; OHM/TADS , 1996; RTECS , 1996)

USES/FORMS/SOURCES

USES

Isooctyl alcohol is used as a solvent and chemical intermediate to produce plasticizers (mainly diisoctyl phthalate) and other products (ACGIH, 1991; Clayton & Clayton, 1994).
It is used as a resin solvent, anti-foaming agent, emulsifier, and as a reagent when the isooctyl group is introduced into other compounds. It also is used as an intermediate for nonionic detergents and surfactants, in cutting and lubricating oils, hydraulic fluids, and in synthetic drying oils (Lewis, 1993).
Isooctyl alcohol is used to prepare esters of adipic sebacic, azelaic, and trimellitic acids and as a solvent for lacquers, fats, oils, waxes, rubber formulations, nitrocellulose, urea, enamels, and alkyd varnishes. It also is used in ceramics, paper coatings, textiles, and latex rubbers (Clayton & Clayton, 1994; Hathaway et al, 1991).

SOURCES

Isooctyl alcohol is produced when a selected C7 hydrocarbon fraction is reacted with carbon monoxide and hydrogen. The reaction must occur in the presence of a catalyst and at pressures up to 3000 psi. Crude alcohol can then be recovered and purified (Lewis, 1993).

-CLINICAL EFFECTS

GENERAL CLINICAL EFFECTS

Isooctyl alcohol is a CNS depressant and an eye, skin, and mucous membrane irritant. Central nervous symptoms may include headache, giddiness, ataxia, confusion, muscle weakness, delirium, and coma. Cough and dyspnea may also be noted. Death may occur from respiratory failure. Disturbances in cardiac rhythm have been noted. Gastrointestinal symptoms from exposure include nausea, vomiting, and diarrhea.

Occasional complications include gastrointestinal hemorrhage, renal damage with glycosuria, liver damage, cardiac failure, and pulmonary edema.

Anesthesia and death have been reported following dermal exposure in experimental animals. Evidence of liver and kidney effects have been noted in experimental animals with chronic exposure to high levels.

POTENTIAL HEALTH HAZARDS - EMERGENCY RESPONSE GUIDEBOOK, GUIDE 131 (ERG, 2004)

TOXIC; may be fatal if inhaled, ingested or absorbed through skin.
Inhalation or contact with some of these materials will irritate or burn skin and eyes.
Fire will produce irritating, corrosive and/or toxic gases.
Vapors may cause dizziness or suffocation.
Runoff from fire control or dilution water may cause pollution.

-MEDICAL TREATMENT

LIFE SUPPORT

Support respiratory and cardiovascular function.

SUMMARY

FIRST AID - EMERGENCY RESPONSE GUIDEBOOK, GUIDE 131 (ERG, 2004)

Move victim to fresh air.
Call 911 or emergency medical service.
Give artificial respiration if victim is not breathing.
Do not use mouth-to-mouth method if victim ingested or inhaled the substance; give artificial respiration with the aid of a pocket mask equipped with a one-way valve or other proper respiratory medical device.
Administer oxygen if breathing is difficult.
Remove and isolate contaminated clothing and shoes.
In case of contact with substance, immediately flush skin or eyes with running water for at least 20 minutes.
Wash skin with soap and water.
Keep victim warm and quiet.
In case of burns, immediately cool affected skin for as long as possible with cold water. Do not remove clothing if adhering to skin.
Effects of exposure (inhalation, ingestion or skin contact) to substance may be delayed.
Ensure that medical personnel are aware of the material(s) involved and take precautions to protect themselves.

FIRST AID

FIRST AID

EYE EXPOSURE - Immediately wash the eyes with large amounts of water, occasionally lifting the lower and upper lids. Get medical attention immediately. Contact lenses should not be worn when working with this chemical.
DERMAL EXPOSURE - Immediately wash the contaminated skin with soap and water. If this chemical penetrates the clothing, immediately remove the clothing, wash the skin with soap and water, and get medical attention promptly.
INHALATION EXPOSURE - Move the exposed person to fresh air at once. If breathing has stopped, perform artificial respiration. Keep the affected person warm and at rest. Get medical attention as soon as possible.
ORAL EXPOSURE - If this chemical has been swallowed, get medical attention immediately.
TARGET ORGANS - Eyes, skin, and respiratory system (National Institute for Occupational Safety and Health, 2007).

GENERAL

Move victims of inhalation exposure from the toxic environment and administer 100% humidified supplemental oxygen with assisted ventilation as required. Exposed skin and eyes should be copiously flushed with water. Because of the potential for rapid onset of CNS depression or seizures with possible aspiration of gastric contents, EMESIS SHOULD NOT BE INDUCED. Cautious gastric lavage followed by administration of activated charcoal may be of benefit if the patient is seen soon after the exposure.

INHALATION EXPOSURE

INHALATION: Move patient to fresh air. Monitor for respiratory distress. If cough or difficulty breathing develops, evaluate for respiratory tract irritation, bronchitis, or pneumonitis. Administer oxygen and assist ventilation as required. Treat bronchospasm with an inhaled beta2-adrenergic agonist. Consider systemic corticosteroids in patients with significant bronchospasm.
If bronchospasm and wheezing occur, consider treatment with inhaled sympathomimetic agents.
ACUTE LUNG INJURY: Maintain ventilation and oxygenation and evaluate with frequent arterial blood gases and/or pulse oximetry monitoring. Early use of PEEP and mechanical ventilation may be needed.

DERMAL EXPOSURE

DECONTAMINATION: Remove contaminated clothing and jewelry and place them in plastic bags. Wash exposed areas with soap and water for 10 to 15 minutes with gentle sponging to avoid skin breakdown. A physician may need to examine the area if irritation or pain persists (Burgess et al, 1999).
Treat dermal irritation or burns with standard topical therapy. Patients developing dermal hypersensitivity reactions may require treatment with systemic or topical corticosteroids or antihistamines.

EYE EXPOSURE

DECONTAMINATION: Remove contact lenses and irrigate exposed eyes with copious amounts of room temperature 0.9% saline or water for at least 15 minutes. If irritation, pain, swelling, lacrimation, or photophobia persist after 15 minutes of irrigation, the patient should be seen in a healthcare facility.

ORAL EXPOSURE

Because of the potential for CNS depression or gastrointestinal tract irritation, do not induce emesis.
Significant esophageal or gastrointestinal tract irritation or burns may occur following ingestion. The possible benefit of early removal of some ingested material by cautious gastric lavage must be weighed against potential complications of bleeding or perforation.
GASTRIC LAVAGE: Consider after ingestion of a potentially life-threatening amount of poison if it can be performed soon after ingestion (generally within 1 hour). Protect airway by placement in the head down left lateral decubitus position or by endotracheal intubation. Control any seizures first.

CONTRAINDICATIONS: Loss of airway protective reflexes or decreased level of consciousness in unintubated patients; following ingestion of corrosives; hydrocarbons (high aspiration potential); patients at risk of hemorrhage or gastrointestinal perforation; and trivial or non-toxic ingestion.

ACTIVATED CHARCOAL: Administer charcoal as a slurry (240 mL water/30 g charcoal). Usual dose: 25 to 100 g in adults/adolescents, 25 to 50 g in children (1 to 12 years), and 1 g/kg in infants less than 1 year old.
Observe patients with ingestion carefully for the possible development of esophageal or gastrointestinal tract irritation or burns. If signs or symptoms of esophageal irritation or burns are present, consider endoscopy to determine the extent of injury.

-RANGE OF TOXICITY

MINIMUM LETHAL EXPOSURE

GENERAL/SUMMARY

Complications due to isooctyl alcohol exposure include death from respiratory failure and cardiac failure. Exposure levels were not reported (HSDB , 1996).

ANIMAL DATA

Rabbits experienced anesthesia and death after a moderately short period of skin exposure to isooctyl alcohol. The concentration of the compound and duration of exposure were not specified (ACGIH, 1991).

MAXIMUM TOLERATED EXPOSURE

GENERAL/SUMMARY

Serious poisoning from isooctyl alcohols have not been reported in the occupational setting (Clayton & Clayton, 1994). However, HSDB (1996) cites various symptoms that may result from exposure, including central nervous system and gastrointestinal complications.

Carcinogenicity Ratings for CAS26952-21-6 :

ACGIH (American Conference of Governmental Industrial Hygienists, 2010): Not Listed ; Listed as: Isooctyl alcohol
EPA (U.S. Environmental Protection Agency, 2011): Not Listed
IARC (International Agency for Research on Cancer (IARC), 2016; International Agency for Research on Cancer, 2015; IARC Working Group on the Evaluation of Carcinogenic Risks to Humans, 2010; IARC Working Group on the Evaluation of Carcinogenic Risks to Humans, 2010a; IARC Working Group on the Evaluation of Carcinogenic Risks to Humans, 2008; IARC Working Group on the Evaluation of Carcinogenic Risks to Humans, 2007; IARC Working Group on the Evaluation of Carcinogenic Risks to Humans, 2006; IARC, 2004): Not Listed
NIOSH (National Institute for Occupational Safety and Health, 2007): Not Listed ; Listed as: Isooctyl alcohol
MAK (DFG, 2002): Not Listed
NTP (U.S. Department of Health and Human Services, Public Health Service, National Toxicology Project ): Not Listed

TOXICITY AND RISK ASSESSMENT VALUES

EPA IRIS

EPA Risk Assessment Values for CAS26952-21-6 (U.S. Environmental Protection Agency, 2011):

Not Listed

TOXICITY VALUES

References: Clayton & Clayton, 1994 HSDB, 1996 RTECS, 1996 Note: All values are from RTECS 1996, unless otherwise noted.
- LD50- (SKIN)GUINEA_PIG:
- LD50- (ORAL)MOUSE:
- LD50- (SKIN)RABBIT:
- LD50- (ORAL)RAT:

CALCULATIONS

AMBIENT CONVERSIONS

CONVERSION FACTORS

1 ppm = 5.41 mg/m(3) (NIOSH , 1996)

-STANDARDS AND LABELS

WORKPLACE STANDARDS

ACGIH TLV Values for CAS26952-21-6 (American Conference of Governmental Industrial Hygienists, 2010):

Editor's Note: The listed values are recommendations or guidelines developed by ACGIH(R) to assist in the control of health hazards. They should only be used, interpreted and applied by individuals trained in industrial hygiene. Before applying these values, it is imperative to read the introduction to each section in the current TLVs(R) and BEI(R) Book and become familiar with the constraints and limitations to their use. Always consult the Documentation of the TLVs(R) and BEIs(R) before applying these recommendations and guidelines.

Adopted Value

Isooctyl alcohol

TLV:

TLV-TWA: 50 ppm
TLV-STEL:
TLV-Ceiling:

Notations and Endnotes:

Carcinogenicity Category: Not Listed
Codes: Skin
Definitions:

Skin: This refers to the potential significant contribution to the overall exposure by the cutaneous route, including mucous membranes and the eyes, either by contact with vapors or, of likely greater significance, by direct skin contact with the substance. It should be noted that although some materials are capable of causing irritation, dermatitis, and sensitization in workers, these properties are not considered relevant when assigning a skin notation. Rather, data from acute dermal studies and repeated dose dermal studies in animals or humans, along with the ability of the chemical to be absorbed, are integrated in the decision-making toward assignment of the skin designation. Use of the skin designation provides an alert that air sampling would not be sufficient by itself in quantifying exposure from the substance and that measures to prevent significant cutaneous absorption may be warranted. Please see "Definitions and Notations" (in TLV booklet) for full definition.

TLV Basis - Critical Effect(s): URT irr
Molecular Weight: 130.23

For gases and vapors, to convert the TLV from ppm to mg/m(3):

[(TLV in ppm)(gram molecular weight of substance)]/24.45

For gases and vapors, to convert the TLV from mg/m(3) to ppm:

[(TLV in mg/m(3))(24.45)]/gram molecular weight of substance

AIHA WEEL Values for CAS26952-21-6 (AIHA, 2006):

Not Listed

NIOSH REL and IDLH Values for CAS26952-21-6 (National Institute for Occupational Safety and Health, 2007):

Listed as: Isooctyl alcohol
REL:

TWA: 50 ppm (270 mg/m(3))
STEL:
Ceiling:
Carcinogen Listing: (Not Listed) Not Listed
Skin Designation: [skin]

Indicates the potential for dermal absorption; skin exposure should be prevented as necessary through the use of good work practices and gloves, coveralls, goggles, and other appropriate equipment.

Note(s):

IDLH: Not Listed

OSHA PEL Values for CAS26952-21-6 (U.S. Occupational Safety, and Health Administration (OSHA), 2010):

Not Listed

OSHA List of Highly Hazardous Chemicals, Toxics, and Reactives for CAS26952-21-6 (U.S. Occupational Safety and Health Administration, 2010):

Not Listed

ENVIRONMENTAL STANDARDS

EPA CERCLA, Hazardous Substances and Reportable Quantities for CAS26952-21-6 (U.S. Environmental Protection Agency, 2010):

Not Listed

EPA CERCLA, Hazardous Substances and Reportable Quantities, Radionuclides for CAS26952-21-6 (U.S. Environmental Protection Agency, 2010):

Not Listed

EPA RCRA Hazardous Waste Number for CAS26952-21-6 (U.S. Environmental Protection Agency, 2010b):

Not Listed
Editor's Note: The D, F, and K series waste numbers and Appendix VIII to Part 261 -- Hazardous Constituents were not included. Please refer to 40 CFR Part 261.

EPA SARA Title III, Extremely Hazardous Substance List for CAS26952-21-6 (U.S. Environmental Protection Agency, 2010):

Not Listed

EPA SARA Title III, Community Right-to-Know for CAS26952-21-6 (40 CFR 372.65, 2006; 40 CFR 372.28, 2006):

Not Listed

DOT List of Marine Pollutants for CAS26952-21-6 (49 CFR 172.101 - App. B, 2005):

Not Listed

EPA TSCA Inventory for CAS26952-21-6 (EPA, 2005):

Listed as: Isooctanol

SHIPPING REGULATIONS

SURFACE

DOT -- Table of Hazardous Materials and Special Provisions (49 CFR 172.101, 2005):

Not Listed

ICAO International Shipping Name (ICAO, 2002):

Not Listed

LABELS

NFPA

NFPA Hazard Ratings for CAS26952-21-6 (NFPA, 2002):

Listed as: Isooctyl Alcohol
Hazard Ratings:

Health Rating (Blue): 3

(3) Seriously toxic material. Short term exposure could cause serious temporary or residual injury even though prompt medical treatment is given. Includes known or suspect small animal carcinogens, mutagens, or teratogens.

Flammability Rating (Red): 2

(2) Combustible. Materials that must be moderately heated before ignition can occur. Including liquids having a flash point above 100 degrees F, and solids that readily give off flammable vapors.

Instability Rating (Yellow): 0

(0) Materials which are normally stable, even under fire conditions, and which are not reactive with water.

Oxidizer/Water-Reactive Designation: Not Listed

-HANDLING AND STORAGE

STORAGE

CONTAINER

To transport, store in 55-gallon drums in tank cars (OHM/TADS , 1996).

INCOMPATIBILITIES

No incompatibilities or reactivities have been reported (NIOSH , 1996).

-PERSONAL PROTECTION

SUMMARY

RECOMMENDED PROTECTIVE CLOTHING - EMERGENCY RESPONSE GUIDEBOOK, GUIDE 131 (ERG, 2004)

Wear positive pressure self-contained breathing apparatus (SCBA).
Wear chemical protective that is specifically recommended by the manufacturer. It may provide little or no thermal protection.
Structural firefighters' protective clothing provides limited protection in fire situations ONLY; it is not effective in spill situations where direct contact with the substance is possible.

EYE/FACE PROTECTION

To prevent eye contact, workers should wear appropriate eye protection (NIOSH , 1996).

PROTECTIVE CLOTHING

CHEMICAL PROTECTIVE CLOTHING. Search results for CAS 26952-21-6.

Specific recommendations and test data for this chemical were not found in the available manufacturers' product literature. A complete list of consulted manufacturers and references is presented below.

-PHYSICAL HAZARDS

FIRE HAZARD

SUMMARY

Editor's Note: This material is not listed in the Emergency Response Guidebook. Based on the material's physical and chemical properties, toxicity, or chemical group, a guide has been assigned. For additional technical information, contact one of the emergency response telephone numbers listed under Public Safety Measures.
POTENTIAL FIRE OR EXPLOSION HAZARDS - EMERGENCY RESPONSE GUIDEBOOK, GUIDE 131 (ERG, 2004)
- HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames.
- Vapors may form explosive mixtures with air.
- Vapors may travel to source of ignition and flash back.
- Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks).
- Vapor explosion and poison hazard indoors, outdoors or in sewers.
- Those substances designated with a "P" may polymerize explosively when heated or involved in a fire.
- Runoff to sewer may create fire or explosion hazard.
- Containers may explode when heated.
- Many liquids are lighter than water.
Isooctyl alcohol is combustible (Lewis, 1993).
It is very flammable and is dangerous when exposed to heat or flame (OHM/TADS , 1996).

FLAMMABILITY CLASSIFICATION

NFPA Flammability Rating for CAS26952-21-6 (NFPA, 2002):

Listed as: Isooctyl Alcohol
Flammability Rating: 2

(2) Combustible. Materials that must be moderately heated before ignition can occur. Including liquids having a flash point above 100 degrees F, and solids that readily give off flammable vapors.

FIRE CONTROL/EXTINGUISHING AGENTS

FIRE PRECAUTIONS - EMERGENCY RESPONSE GUIDEBOOK, GUIDE 131 (ERG, 2004)

CAUTION: All these products have a very low flash point: Use of water spray when fighting fire may be inefficient.

SMALL FIRE PRECAUTIONS - EMERGENCY RESPONSE GUIDEBOOK, GUIDE 131 (ERG, 2004)

Dry chemical, CO2, water spray or alcohol-resistant foam.

LARGE FIRE PRECAUTIONS - EMERGENCY RESPONSE GUIDEBOOK, GUIDE 131 (ERG, 2004)

Water spray, fog or alcohol-resistant foam.
Move containers from fire area if you can do it without risk.
Dike fire control water for later disposal; do not scatter the material.
Use water spray or fog; do not use straight streams.

TANK OR CAR/TRAILER LOAD FIRE PRECAUTIONS - EMERGENCY RESPONSE GUIDEBOOK, GUIDE 131 (ERG, 2004)

Fight fire from maximum distance or use unmanned hose holders or monitor nozzles.
Cool containers with flooding quantities of water until well after fire is out.
Withdraw immediately in case of rising sound from venting safety devices or discoloration of tank.
ALWAYS stay away from tanks engulfed in fire.
For massive fire, use unmanned hose holders or monitor nozzles; if this is impossible, withdraw from area and let fire burn.

NFPA Extinguishing Methods for CAS26952-21-6 (NFPA, 2002):

Listed as: Isooctyl Alcohol
Extinguishing Method(s): 5

5: Flammable liquid fires can be extinguished using carbon dioxide, dry chemical, foam, and vaporizing liquid extinguishers, as long as the fires are small to moderate in size and the flammable liquid reservoir is shallow. Use of foam to form a blanket over a flammable liquid is not effective when the liquid is water-soluble. Certain alcohol resistant foams are effective extinguishing agents for polar, non-polar, and water-soluble liquid fires. These foams are preferred for fighting flammable liquid fires except those that involve water reactive flammable liquids.

COMBUSTION TOXICITY

Acrid fumes and smoke are emitted when isooctyl alcohol is heated to decomposition (Lewis, 1996).

DUST/VAPOR HAZARD

Isooctyl alcohol will emit acrid smoke and fumes when heated to decomposition (Lewis, 1996).

According to CHRIS (1996), vapors are not irritating to the eyes and throat; however, NIOSH (1996) states that exposure symptoms include eye and throat irritation.

REACTIVITY HAZARD

The compound emits acrid smoke and fumes when heated to decomposition (Lewis, 1996).

EVACUATION PROCEDURES

SUMMARY

Editor's Note: This material is not listed in the Table of Initial Isolation and Protective Action Distances.

SPILL - PUBLIC SAFETY EVACUATION DISTANCES - EMERGENCY RESPONSE GUIDEBOOK, GUIDE 131 (ERG, 2004)

Increase, in the downwind direction, as necessary, the isolation distance of at least 50 meters (150 feet) in all directions.

FIRE - PUBLIC SAFETY EVACUATION DISTANCES - EMERGENCY RESPONSE GUIDEBOOK, GUIDE 131 (ERG, 2004)

If tank, rail car or tank truck is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions.

PUBLIC SAFETY MEASURES - EMERGENCY RESPONSE GUIDEBOOK, GUIDE 131(ERG, 2004)

CALL Emergency Response Telephone Number on Shipping Paper first. If Shipping Paper not available or no answer, refer to appropriate telephone number:

MEXICO:

SETIQ:

01-800-00-214-00 in the Mexican Republic;
For calls originating in Mexico City and the Metropolitan Area: 5559-1588;
For calls originating elsewhere, call: 011-52-555-559-1588.

CENACOM:

01-800-00-413-00 in the Mexican Republic;
For calls originating in Mexico City and the Metropolitan Area: 5550-1496, 5550-1552, 5550-1485, or 5550-4885;
For calls originating elsewhere, call: 011-52-555-550-1496, or 011-52-555-550-1552; 011-52-555-550-1485, or 011-52-555-550-4885.

ARGENTINA:

CIQUIME:

0-800-222-2933 in the Republic of Argentina;
For calls originating elsewhere, call: +54-11-4613-1100.

BRAZIL:

PRÓ-QUÍMICA:

0-800-118270 (Toll-free in Brazil);
For calls originating elsewhere, call: +55-11-232-1144 (Collect calls are accepted).

COLUMBIA:

CISPROQUIM:

01-800-091-6012 in Colombia;
For calls originating in Bogotá, Colombia, call: 288-6012;
For calls originating elsewhere, call: 011-57-1-288-6012.

CANADA:

CANUTEC:

613-996-6666 (Collect calls are accepted);
*666 cellular (in Canada only).

UNITED STATES:

CHEMTREC®:

1-800-424-9300 (Toll-free in the U.S., Canada, and the U.S. Virgin Islands);
703-527-3887 for calls originating elsewhere (Collect calls are accepted).

CHEM-TEL, INC.:

1-800-255-3924 (Toll-free in the U.S., Canada, and the U.S. Virgin Islands);
813-248-0585 for calls originating elsewhere (Collect calls are accepted).

INFOTRAC:

1-800-535-5053 (Toll-free in the U.S., Canada, and the U.S. Virgin Islands);
352-323-3500 for calls originating elsewhere (Collect calls are accepted).

3E COMPANY:

1-800-451-8346 (Toll-free in the U.S., Canada, and the U.S. Virgin Islands);
760-602-8703 for calls originating elsewhere (Collect calls are accepted).

NATIONAL RESPONSE CENTER (NRC):

1-800-424-8802 - (24 hours) (Toll-free in the U.S., Canada, and the U.S. Virgin Islands);
202-267-2675 for calls in the District of Columbia.

MILITARY SHIPMENTS:

703-697-0218 - Explosives/ammunition incidents (Collect calls are accepted);
1-800-851-8061 - All other dangerous goods incidents.

NATIONWIDE POISON CONTROL CENTER (United States only):

1-800-222-1222 (Toll-free in the U.S.).

For additional details see the section entitled "WHO TO CALL FOR ASSISTANCE" under the ERG Instructions.
As an immediate precautionary measure, isolate spill or leak area for at least 50 meters (150 feet) in all directions.
Keep unauthorized personnel away.
Stay upwind.
Keep out of low areas.
Ventilate closed spaces before entering.

Recreational water uses will be affected by an isooctyl alcohol spill. A slick produced from an industrial site may reduce heat transfer or cause hot spots or scaling (OHM/TADS , 1996).

AIHA ERPG Values for CAS26952-21-6 (AIHA, 2006):

Not Listed

DOE TEEL Values for CAS26952-21-6 (U.S. Department of Energy, Office of Emergency Management, 2010):

Not Listed

AEGL Values for CAS26952-21-6 (National Research Council, 2010; National Research Council, 2009; National Research Council, 2008; National Research Council, 2007; NRC, 2001; NRC, 2002; NRC, 2003; NRC, 2004; NRC, 2004; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2006; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2007; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2005; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2005; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2007; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2006; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2006; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2006; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2006; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2006; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2006; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2006; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2006; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2006; United States Environmental Protection Agency Office of Pollution Prevention and Toxics, 2006; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2006; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2007; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2007; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2007; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2007; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2007; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2009; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2009; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2009; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2009; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2009; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2009; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2009; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2009; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2009; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2009; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2009; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2009; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2009; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2007; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2006; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2006; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2006; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2007; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2007; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2007; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2007; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2007; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2005; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2005; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2005; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2005; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2005; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2005; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2005; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2005; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2007; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2005; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2006; 62 FR 58840, 1997; 65 FR 14186, 2000; 65 FR 39264, 2000; 65 FR 77866, 2000; 66 FR 21940, 2001; 67 FR 7164, 2002; 68 FR 42710, 2003; 69 FR 54144, 2004):

Not Listed

NIOSH IDLH Values for CAS26952-21-6 (National Institute for Occupational Safety and Health, 2007):

Not Listed

CONTAINMENT/WASTE TREATMENT OPTIONS

SUMMARY

SPILL OR LEAK PRECAUTIONS - EMERGENCY RESPONSE GUIDEBOOK, GUIDE 131 (ERG, 2004)
- Fully encapsulating, vapor protective clothing should be worn for spills and leaks with no fire.
- ELIMINATE all ignition sources (no smoking, flares, sparks or flames in immediate area).
- All equipment used when handling the product must be grounded.
- Do not touch or walk through spilled material.
- Stop leak if you can do it without risk.
- Prevent entry into waterways, sewers, basements or confined areas.
- A vapor suppressing foam may be used to reduce vapors.
RECOMMENDED PROTECTIVE CLOTHING - EMERGENCY RESPONSE GUIDEBOOK, GUIDE 131 (ERG, 2004)
- Wear positive pressure self-contained breathing apparatus (SCBA).
- Wear chemical protective that is specifically recommended by the manufacturer. It may provide little or no thermal protection.
- Structural firefighters' protective clothing provides limited protection in fire situations ONLY; it is not effective in spill situations where direct contact with the substance is possible.
Should a water leak or spill occur, notify local health and wildlife officials and operators of nearby water intakes (CHRIS , 1996).
The compound may be dangerous if it enters water intakes (CHRIS , 1996).

SMALL LEAK/SPILL

SMALL SPILL PRECAUTIONS - EMERGENCY RESPONSE GUIDEBOOK, GUIDE 131 (ERG, 2004)
- Absorb with earth, sand or other non-combustible material and transfer to containers for later disposal.
- Use clean non-sparking tools to collect absorbed material.

LARGE LEAK/SPILL

LARGE SPILL PRECAUTIONS - EMERGENCY RESPONSE GUIDEBOOK, GUIDE 131 (ERG, 2004)
- Dike far ahead of liquid spill for later disposal.
- Water spray may reduce vapor; but may not prevent ignition in closed spaces.

WASTE TREATMENT OPTIONS

PHYSICAL TREATMENT

Spray isooctyl alcohol into an incinerator or burn it in paper packaging. If necessary, add a flammable solvent (OHM/TADS , 1996).
To clean up a slick, use oil skimming equipment or apply sorbent foams (OHM/TADS , 1996).
Waste management activities associated with material disposition are unique to individual situations. Proper waste characterization and decisions regarding waste management should be coordinated with the appropriate local, state, or federal authorities to ensure compliance with all applicable rules and regulations.

-ENVIRONMENTAL HAZARD MANAGEMENT

POLLUTION HAZARD

Isooctyl alcohol in effluents may be released to the environment in close proximity to where the compound is used or produced (HSDB, 2004).

ENVIRONMENTAL FATE AND KINETICS

Based on a vapor pressure of 7.70x10(-2) mmHg at 25 degrees C, it is expected that, in ambient air, the compound exists completely in the vapor phase (HSDB, 2004).
The estimated rate constant for the vapor-phase reaction of isooctyl alcohol with photochemically produced hydroxyl radicals in air is 1.20x10(-11) cm(3)/molecule-sec at 25 degrees C. This corresponds to a 1.3-day atmospheric half-life at an atmospheric concentration of 5x10(5) hydroxyl radicals/cm(3) (HSDB, 2004).

WATER

SURFACE WATER
- Isooctyl alcohol volatilization from natural waters is expected to be an important fate process. This is based on a Henry's Law constant of 3.88x10(-5) atm-m(3)/mole. In a model pond, the volatilization half-life was estimated to be 54 days (HSDB, 2004).

SOIL

TERRESTRIAL
- Isooctyl alcohol volatilization from moist surface soils may be environmentally important. This information is based on an estimated Henry's Law constant of 3.88x10(-5) atm-m(3)/mole (HSDB, 2004).
- Koc values for isooctyl alcohol range from 125 to 950 for sediments, suspended solids, and soil (HSDB, 2004).

ABIOTIC DEGRADATION

Isooctyl alcohol is generally resistant to hydrolysis or direct photolysis in the environment. Isooctyl alcohol may biodegrade rapidly in acclimated soil and water (HSDB, 2004).

BIODEGRADATION

Based on studies of n-octanol isomers, it is expected that isooctyl alcohol will rapidly biodegrade in acclimated terrestrial and aquatic systems (HSDB, 2004).

BIOACCUMULATION

OTHER

OTHER
- Aquatic Organisms:

-PHYSICAL/CHEMICAL PROPERTIES

MOLECULAR WEIGHT

130.26 (Budavari, 1996)

DESCRIPTION/PHYSICAL STATE

Isooctyl alcohol is a mixture of closely related isomeric primary alcohols with branched chains with the general formula RCH2OH, in which R represents a branched heptyl radical. The branching is mostly represented by methyl groups located in the 3-, 4-, or 5-positions (Budavari, 1996).

The olefin feedstock is primarily responsible for the substance's composition and CAS number (Clayton & Clayton, 1994).

It typically is a mixture containing 70 to 80% dimethyl-1-hexanols, 10 to 20% methyl-1-heptanols, and 5 to 10% other homologous primary alcohols (ACGIH, 1991).

Isooctyl alcohol is a clear and colorless liquid and possesses a faint pleasant odor (AAR, 1994).

VAPOR PRESSURE

0.4 mmHg (NIOSH , 1996)

SPECIFIC GRAVITY

OTHER TEMPERATURE AND/OR PRESSURE

0.832 (at 20/20 degrees C) (Lewis, 1993)

TEMPERATURE AND/OR PRESSURE NOT LISTED

0.83 (NIOSH , 1996)

DENSITY

OTHER TEMPERATURE AND/OR PRESSURE

0.832 g/mL (at 20 degrees C) (ACGIH, 1991)

FREEZING/MELTING POINT

FREEZING POINT

< -105 degrees F (NIOSH , 1996)

MELTING POINT

< 100 degrees C (HSDB , 1996)

BOILING POINT

186 degrees C; 367 degrees F (NIOSH , 1996)

184-191 degrees C (ACGIH, 1991)

FLASH POINT

82 degrees C; 180 degrees F (open cup) (ACGIH, 1991; NIOSH , 1996)

EXPLOSIVE LIMITS

LOWER

0.9% (NIOSH , 1996)

UPPER

5.7% (NIOSH , 1996)

SOLUBILITY

IN WATER

Isooctyl alcohol is insoluble in water (NIOSH , 1996).
Water solubility is 640 mg/L at 25 degrees C (HSDB , 1996)

IN ORGANIC SOLVENTS

It is soluble in ethyl alcohol and ether (ACGIH, 1991).

OTHER/PHYSICAL

ODOR THRESHOLD

Data not available (CHRIS , 1996)

SURFACE TENSION

27.53 dynes/cm (at 20 degrees C) (HSDB , 1996)
29.5 dynes/cm = 0.0295 N/m (at 20 degrees C) (CHRIS , 1996)

HEAT OF COMBUSTION

-17,400 Btu/lb = -9650 cal/g = -404 X 10(5) J/kg (estimated) (CHRIS , 1996)

VISCOSITY

10.6 cP (at 15 degrees C) (HSDB , 1996)

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ISOOCTYL ALCOHOL

Classification | Information to evaluate chemical incidents

Information to evaluate chemical incidents

Information to evaluate chemical incidents

Information to evaluate chemical incidents