CYANURIC FLUORIDE

Editor's Note: This material is not listed in the Emergency Response Guidebook. Based on the material's physical and chemical properties, toxicity, or chemical group, a guide has been assigned. For additional technical information, contact one of the emergency response telephone numbers listed under Public Safety Measures.

MOLECULAR FORMULA

C3-F3-N3

ERG GUIDE NUMBER

153-SUBSTANCES - TOXIC AND/OR CORROSIVE (COMBUSTIBLE)

SYNONYM REFERENCE

(RTECS , 1990; EPA, 1985)

USES/FORMS/SOURCES

USES

Cyanuric fluoride is commercially available for biochemical applications. In particular, it is used as a specific reagent for tyrosine. Fiber-reactive dyes based on cyanuric fluorides is also an emerging major application (HSDB, 2003).

FORMS

Cyanuric fluoride is a colorless liquid (HSDB, 2003).

SOURCES

Cyanuric fluoride can be prepared from cyanuric chloride using a fluorinating agent, such as pentavalent antimony chlorofluoride, silver monofluoride, potassium fluoride, sodium fluoride, potassium fluorosulfinate, or sulfur tetrafluoride (HSDB, 2003).

-CLINICAL EFFECTS

GENERAL CLINICAL EFFECTS

Very little information is available about cyanuric fluoride and its potential toxicity. The material readily penetrates through the skin, and is quite irritating. At the time of this review, NO DATA INDICATING THAT CYANIDE POISONING CAN OCCUR FOLLOWING EXPOSURE were found.

Should an exposed patient exhibit signs or symptoms of CYANIDE POISONING, REFER to the POTASSIUM CYANIDE management for evaluation and treatment recommendations.

Most of the clinical effects and treatment recommendations below are derived from information regarding the similar chlorinated derivative, CYANURIC CHLORIDE, classified as a moderately toxic substance.

Respiratory tract, skin, and severe eye irritation has been demonstrated in experimental animals exposed to cyanuric chloride. Respiratory tract irritation occurred in exposed humans.
In humans, repeated dermal exposure to low concentrations of cyanuric chloride did not cause irritation, although serious irritation and dermal necrosis have occurred in experimental animals exposed directly to the material.
The similar compound, cyanuric chloride, caused corrosive damage to the gastrointestinal tract when fed at high doses to experimental animals. Subacute feedings of 37 mg/kg per day for 5 weeks caused no ill effects in rabbits.
One older rat study without controls and using only a small number of animals found that cyanuric chloride is a relatively weak carcinogen, causing an increased incidence of fibroadenomas at injection sites, and tumors of the mammary glands, uterus, and prostate. This study has been criticized for several reasons, and does not provide adequate evidence that cyanuric chloride is carcinogenic.

When cyanuric fluoride is heated to decomposition, highly irritating and toxic fumes of fluorides and oxides of nitrogen are released. Exposure to these products of combustion would be predicted to cause eye and respiratory tract irritation, and could lead to the development of chemical pneumonitis or noncardiogenic pulmonary edema.

It is unknown whether or not systemic fluoride poisoning could occur following cyanuric fluoride absorption. However, it would be prudent to observe for such effects as hypocalcemia, hypomagnesemia, hyperkalemia, cardiac dysrhythmias, respiratory depression, hyperactive reflexes with tetany, and hypocoagulability.

POTENTIAL HEALTH HAZARDS - EMERGENCY RESPONSE GUIDEBOOK, GUIDE 153 (ERG, 2004)

TOXIC; inhalation, ingestion or skin contact with material may cause severe injury or death.
Contact with molten substance may cause severe burns to skin and eyes.
Avoid any skin contact.
Effects of contact or inhalation may be delayed.
Fire may produce irritating, corrosive and/or toxic gases.
Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution.

ACUTE CLINICAL EFFECTS

Based on its acute inhalation LC50 of 3100 ppb for 4 hours in rats (RTECS , 1993), cyanuric fluoride is a highly toxic substance. Very little information is available about cyanuric fluoride and its potential toxicity. IT IS NOT KNOWN IF CYANURIC FLUORIDE CAN CAUSE EITHER CYANIDE OR FLUORIDE POISONING.

The material readily penetrates through the skin, and is quite irritating (Griffiths, 1972). The irritant threshold for fumes of the similar compound, cyanuric chloride, in humans was 0.3 mg/m(3) for a one-minute exposure (Blagodatin, 1968).

Respiratory tract, skin, and severe eye irritation and lacrimation have been demonstrated in experimental animals exposed to the closely related substance, cyanuric chloride; respiratory tract irritation was also seen in humans (Blagodatin, 1968).

Exposure to the products of combustion of cyanuric fluoride, fluoride and oxides of nitrogen (Sax & Lewis, 1989), would be predicted to cause eye and respiratory tract irritation, and could lead to the development of chemical pneumonitis or noncardiogenic pulmonary edema.

It is unknown whether or not systemic fluoride poisoning could occur following cyanuric fluoride absorption. Symptoms of acute fluoride poisoning by ingestion include salivation, nausea, abdominal pain, vomiting, diarrhea, nervousness, convulsions, muscle pain, low blood pressure and shock, CNS depression (dizziness, weakness, loss of coordination), GI bleeding, muscle weakness, collapse, breathing difficulty, difficulty speaking, motor unrest (fitfulness), thirst, weak pulse, disturbed color vision, and loss of consciousness. Death is usually from respiratory paralysis or heart failure (HSDB , 1993).

In systemic fluoride poisoning, respirations are first stimulated, then depressed. Should systemic fluoride poisoning occur following absorption of cyanuric fluoride, death might occur from cardiac failure or respiratory paralysis (Heifetz & Horowitz, 1986). Arrhythmias consistent with hyperkalemia have been reported in systemic fluoride poisoning (Baltazar et al, 1980; McIvor et al, 1987).

Cyanide causes symptoms including flushing, nausea, vomiting, palpitations, tachycardia, hyperpnea, headache, dizziness, confusion, hyperventilation, anxiety, agitation, tremors, weakness, stupor, severe metabolic acidosis, cardiac conduction defects and arrhythmias, generalized seizures, and coma (Hall & Rumack, 1986). Death may occur within a few minutes.

Refer to the REPROTEXT documents on CYANIDE and FLUORIDE for more information.

CHRONIC CLINICAL EFFECTS

No information was found on chronic exposure to cyanuric fluoride in humans or animals.

Repeated applications of low concentrations of cyanuric chloride, a related substance, did not cause dermal irritation, but irritation and ulceration were seen in rabbits (Canelli, 1974; Blagodatin, 1968). Cyanuric chloride has caused chronic eczyma and dermal sensitization (HSDB , 1993).

Inhalation of dust from cyanuric chloride, by rats at a concentration of 1.88 mg/m(3) 4 hours daily for 2 and 1/2 months caused a 30% fatality rate, with respiratory tract irritation and liver and kidney damage (CHEMINFO , 1990).

Chronic exposure to cyanides has been reported to cause CNS effects such as insomnia, loss of memory, and tremors, blindness from degeneration of the optic nerve, and goiter (Chaumont, 1960); (Ermans et al, 1972).

More than 6 mg per day of fluoride can produce FLUOROSIS, a condition of excess fluoride in the body characterized by nausea, vomiting, loss of appetite, diarrhea or constipation, anemia, weakness, and stiffness in the joints (ACGIH, 1986).

Chronic exposure to fluoride at levels greater than the TLV can produce OSTEOSCLEROSIS, a painful increase in bone density and calcification of ligaments. Sometimes the latent period is as long as 20 years (ACGIH, 1986).

-FIRST AID

FIRST AID AND PREHOSPITAL TREATMENT

DILUTION

FLUORIDE BINDING - Attempt immediate administration of a fluoride binding substance. Options include milk (one-half to one glassful), chewable calcium carbonate tablets, or milk of magnesia. Avoid large amounts of liquid, since this may induce vomiting.

EMESIS/NOT RECOMMENDED

Do NOT induce vomiting.

-MEDICAL TREATMENT

LIFE SUPPORT

Support respiratory and cardiovascular function.

SUMMARY

FIRST AID - EMERGENCY RESPONSE GUIDEBOOK, GUIDE 153 (ERG, 2004)

Move victim to fresh air.
Call 911 or emergency medical service.
Give artificial respiration if victim is not breathing.
Do not use mouth-to-mouth method if victim ingested or inhaled the substance; give artificial respiration with the aid of a pocket mask equipped with a one-way valve or other proper respiratory medical device.
Administer oxygen if breathing is difficult.
Remove and isolate contaminated clothing and shoes.
In case of contact with substance, immediately flush skin or eyes with running water for at least 20 minutes.
For minor skin contact, avoid spreading material on unaffected skin.
Keep victim warm and quiet.
Effects of exposure (inhalation, ingestion or skin contact) to substance may be delayed.
Ensure that medical personnel are aware of the material(s) involved and take precautions to protect themselves.

FIRST AID

DERMAL EXPOSURE - Prompt decontamination of the affected area is of primary importance. Specific treatment is controversial, with no single type of therapy clearly superior. Topical calcium gluconate gel or magnesium oxide paste has been successful. Local calcium gluconate infiltration may be considered in some cases. Significant systemic absorption from dermal exposure may cause symptomatic hypocalcemia, hyperkalemia, and hypomagnesemia which will require aggressive treatment.
ORAL EXPOSURE - Do NOT induce vomiting. Administer fluoride-binding substance (options include milk, chewable calcium carbonate tablets, milk of magnesia). Consider nasogastric or soft orogastric suction and lavage with 10% calcium gluconate if large and recent ingestion, and spontaneous emesis has not occurred. Monitor and treat hypocalcemia, hypomagnesemia, hyperkalemia parenterally as needed.
EYE EXPOSURE - Irrigate promptly with crystalloid solution (lactated ringer's or normal saline) for at least 30 minutes. Carefully evaluate for eye damage. The patient should be evaluated by an ophthalmologist following appropriate decontamination.
INHALATION EXPOSURE - Move the patient to fresh air and administer 100% humidified supplemental oxygen with assisted ventilation as required. Monitor for respiratory signs and symptoms and treat symptomatically. Nebulized calcium gluconate has been used in the treatment of HF inhalation exposure. However, its clinical efficacy is uncertain (NIOSH , 1998).

-RANGE OF TOXICITY

MINIMUM LETHAL EXPOSURE

GENERAL/SUMMARY

At the time of this review, no specific information on the minimun lethal exposure to cyanuric fluoride was found in available references.

ANIMAL DATA

Median lethal doses for the similar compound, cyanuric chloride, were 350 milligrams/kilogram in mice and 485 milligrams/kilogram in rats (Blagodatin, 1968).
Inhalation of dust by rats from the similar compound, cyanuric chloride, at a concentration of 1.88 milligrams/cubic meter 4 hours daily for 2 and 1/2 months caused a 30 percent fatality rate, with respiratory tract irritation and liver and kidney injury in the survivors (CHEMINFO , 1990).

MAXIMUM TOLERATED EXPOSURE

GENERAL/SUMMARY

At the time of this review, no specific information on the maximum tolerated exposure to cyanuric fluoride was found in available references.
The irritant threshold for fumes of the similar compound, cyanuric chloride, in humans was 0.3 milligrams/cubic meter for a one-minute exposure (Blagodatin, 1968).

ANIMAL DATA

Application of 200 milligrams of the similar compound, cyanuric chloride, caused skin irritation in rabbits, followed by ulceration with repeated exposures (Blagodatin, 1968).
A dose of 3000 milligrams of cyanuric chloride applied to rabbit skin caused no deaths, although severe irritation developed (CHEMINFO , 1990).
The similar compound, cyanuric chloride, caused corrosive damage to the gastrointestinal tract when fed at high doses to experimental animals (HSDB, 1999).
Subacute feedings of 37 milligrams/kilogram per day of cyanuric chloride for 5 weeks caused no ill effects in rabbits (HSDB, 1999; (CHEMINFO , 1990).
No effects were seen in rats fed 20 milligrams/kilogram of cyanuric chloride for 30 days; a reduced weight gain was seen at doses of 100 and 500 milligrams/kilogram daily (CHEMINFO , 1990).

Carcinogenicity Ratings for CAS675-14-9 :

ACGIH (American Conference of Governmental Industrial Hygienists, 2010): Not Listed
EPA (U.S. Environmental Protection Agency, 2011): Not Listed
IARC (International Agency for Research on Cancer (IARC), 2016; International Agency for Research on Cancer, 2015; IARC Working Group on the Evaluation of Carcinogenic Risks to Humans, 2010; IARC Working Group on the Evaluation of Carcinogenic Risks to Humans, 2010a; IARC Working Group on the Evaluation of Carcinogenic Risks to Humans, 2008; IARC Working Group on the Evaluation of Carcinogenic Risks to Humans, 2007; IARC Working Group on the Evaluation of Carcinogenic Risks to Humans, 2006; IARC, 2004): Not Listed
NIOSH (National Institute for Occupational Safety and Health, 2007): Not Listed
MAK (DFG, 2002): Not Listed
NTP (U.S. Department of Health and Human Services, Public Health Service, National Toxicology Project ): Not Listed

TOXICITY AND RISK ASSESSMENT VALUES

EPA IRIS

EPA Risk Assessment Values for CAS675-14-9 (U.S. Environmental Protection Agency, 2011):

Not Listed

TOXICITY VALUES

References: RTECS, 2004; Lewis, 1996 EPA, 1985
- LC50- (INHALATION)RAT:
- LD50- (SKIN)RABBIT:

CALCULATIONS

AMBIENT CONVERSIONS

CONVERSION FACTORS

1 ppm = 7.5 mg/m(3) (CHEMINFO , 1990)

1 g/m(3) = 0.13 ppm (CHEMINFO , 1990)

-STANDARDS AND LABELS

WORKPLACE STANDARDS

ACGIH TLV Values for CAS675-14-9 (American Conference of Governmental Industrial Hygienists, 2010):

Not Listed

AIHA WEEL Values for CAS675-14-9 (AIHA, 2006):

Not Listed

NIOSH REL and IDLH Values for CAS675-14-9 (National Institute for Occupational Safety and Health, 2007):

Not Listed

OSHA PEL Values for CAS675-14-9 (U.S. Occupational Safety, and Health Administration (OSHA), 2010):

Not Listed

OSHA List of Highly Hazardous Chemicals, Toxics, and Reactives for CAS675-14-9 (U.S. Occupational Safety and Health Administration, 2010):

Threshold Quantity, in pounds:100

ENVIRONMENTAL STANDARDS

EPA CERCLA, Hazardous Substances and Reportable Quantities for CAS675-14-9 (U.S. Environmental Protection Agency, 2010):

Not Listed

EPA CERCLA, Hazardous Substances and Reportable Quantities, Radionuclides for CAS675-14-9 (U.S. Environmental Protection Agency, 2010):

Not Listed

EPA RCRA Hazardous Waste Number for CAS675-14-9 (U.S. Environmental Protection Agency, 2010b):

Not Listed
Editor's Note: The D, F, and K series waste numbers and Appendix VIII to Part 261 -- Hazardous Constituents were not included. Please refer to 40 CFR Part 261.

EPA SARA Title III, Extremely Hazardous Substance List for CAS675-14-9 (U.S. Environmental Protection Agency, 2010):

Listed as: Cyanuric Fluoride
Reportable Quantity, in pounds: 100

Only the statutory or final RQ is shown. For more information, see 40 CFR table 302.4.

Threshold Planning Quantity, in pounds:

100
Amount necessary to be covered by this standard. See 40 CFR 355.30.

Note(s): Not Listed

EPA SARA Title III, Community Right-to-Know for CAS675-14-9 (40 CFR 372.65, 2006; 40 CFR 372.28, 2006):

Not Listed

DOT List of Marine Pollutants for CAS675-14-9 (49 CFR 172.101 - App. B, 2005):

Not Listed

EPA TSCA Inventory for CAS675-14-9 (EPA, 2005):

Listed as: 1,3,5-Triazine, 2,4,6-trifluoro-

SHIPPING REGULATIONS

SURFACE

DOT -- Table of Hazardous Materials and Special Provisions (49 CFR 172.101, 2005):

Not Listed

ICAO International Shipping Name (ICAO, 2002):

Not Listed

LABELS

NFPA

NFPA Hazard Ratings for CAS675-14-9 (NFPA, 2002):

Not Listed

-PERSONAL PROTECTION

SUMMARY

RECOMMENDED PROTECTIVE CLOTHING - EMERGENCY RESPONSE GUIDEBOOK, GUIDE 153 (ERG, 2004)

Wear positive pressure self-contained breathing apparatus (SCBA).
Wear chemical protective clothing that is specifically recommended by the manufacturer. It may provide little or no thermal protection.
Structural firefighters' protective clothing provides limited protection. fire situations ONLY; it is not effective in spill situations where direct contact with the substance is possible.

Avoid inhalation of and skin contact with cyanuric fluoride. Wear respiratory protection and full protective clothing (EPA, 1985).

Use of full protective clothing is recommended for safe handling of cyanuric fluoride (EPA, 1985).

RESPIRATORY PROTECTION

Respiratory protection is recommended for safe handling and use of cyanuric fluoride (EPA, 1985).

Refer to "Recommendations for respirator selection" in the NIOSH Pocket Guide to Chemical Hazards on TOMES Plus(R) for respirator information.

PROTECTIVE CLOTHING

CHEMICAL PROTECTIVE CLOTHING. Search results for CAS 675-14-9.

Specific recommendations and test data for this chemical were not found in the available manufacturers' product literature. A complete list of consulted manufacturers and references is presented below.

-PHYSICAL HAZARDS

FIRE HAZARD

SUMMARY

Editor's Note: This material is not listed in the Emergency Response Guidebook. Based on the material's physical and chemical properties, toxicity, or chemical group, a guide has been assigned. For additional technical information, contact one of the emergency response telephone numbers listed under Public Safety Measures.
POTENTIAL FIRE OR EXPLOSION HAZARDS - EMERGENCY RESPONSE GUIDEBOOK, GUIDE 153 (ERG, 2004)
- Combustible material: may burn but does not ignite readily.
- When heated, vapors may form explosive mixtures with air: indoors, outdoors and sewers explosion hazards.
- Those substances designated with a "P" may polymerize explosively when heated or involved in a fire.
- Contact with metals may evolve flammable hydrogen gas.
- Containers may explode when heated.
- Runoff may pollute waterways.
- Substance may be transported in a molten form.

FLAMMABILITY CLASSIFICATION

NFPA Flammability Rating for CAS675-14-9 (NFPA, 2002):

Not Listed

FIRE CONTROL/EXTINGUISHING AGENTS

SMALL FIRE PRECAUTIONS - EMERGENCY RESPONSE GUIDEBOOK, GUIDE 153 (ERG, 2004)

Dry chemical, CO2 or water spray.

LARGE FIRE PRECAUTIONS - EMERGENCY RESPONSE GUIDEBOOK, GUIDE 153 (ERG, 2004)

Dry chemical, CO2, alcohol-resistant foam or water spray.
Move containers from fire area if you can do it without risk.
Dike fire control water for later disposal; do not scatter the material.

TANK OR CAR/TRAILER LOAD FIRE PRECAUTIONS - EMERGENCY RESPONSE GUIDEBOOK, GUIDE 153 (ERG, 2004)

Fight fire from maximum distance or use unmanned hose holders or monitor nozzles.
Do not get water inside containers.
Cool containers with flooding quantities of water until well after fire is out.
Withdraw immediately in case of rising sound from venting safety devices or discoloration of tank.
ALWAYS stay away from tanks engulfed in fire.

NFPA Extinguishing Methods for CAS675-14-9 (NFPA, 2002):

Not Listed

For the similar compound, cyanuric chloride, use carbon dioxide, dry chemical powder, alcohol foam or polymer foam on fires. Do not use water. Water can react violently with cyanuric chloride (CHEMINFO , 1990).

COMBUSTION TOXICITY

When heated to decomposition, cyanuric fluoride emits very toxic fumes of fluorides and nitrogen oxides (EPA, 1985; Sax & Lewis, 1989).

DUST/VAPOR HAZARD

When heated to decomposition, cyanuric fluoride emits very toxic fumes of fluorides and nitrogen oxides (EPA, 1985; Sax & Lewis, 1989).

REACTIVITY HAZARD

When heated to decomposition, cyanuric fluoride emits very toxic fumes of fluorides and nitrogen oxides (EPA, 1985; Lewis, 1996).

The similar compound, cyanuric chloride, can react violently with water to produce cyanuric acid, hydrochloric acid, and heat (CHEMINFO , 1990).

EVACUATION PROCEDURES

SUMMARY

Initial Isolation and Protective Action Distances (ERG, 2004)

Data presented from the Emergency Response Guidebook Table of Initial Isolation and Protective Action Distances are for use when a spill has occurred and there is no fire. If there is a fire, or if a fire is involved, evacuation information presented under FIRE - PUBLIC SAFETY EVACUATION DISTANCES should be used.
Generally, a small spill is one that involves a single, small package such as a drum containing up to approximately 200 liters, a small cylinder, or a small leak from a large package. A large spill is one that involves a spill from a large package, or multiple spills from many small packages.
Suggested distances to protect from vapors of toxic-by-inhalation and/or water-reactive materials during the first 30 minutes following the spill.

SPILL - PUBLIC SAFETY EVACUATION DISTANCES - EMERGENCY RESPONSE GUIDEBOOK, GUIDE 153 (ERG, 2004)

Increase, in the downwind direction, as necessary, the isolation distance of at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids in all directions.

FIRE - PUBLIC SAFETY EVACUATION DISTANCES - EMERGENCY RESPONSE GUIDEBOOK, GUIDE 153 (ERG, 2004)

If tank, rail car or tank truck is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions.

PUBLIC SAFETY MEASURES - EMERGENCY RESPONSE GUIDEBOOK, GUIDE 153 (ERG, 2004)

CALL Emergency Response Telephone Number on Shipping Paper first. If Shipping Paper not available or no answer, refer to appropriate telephone number:

MEXICO:

SETIQ:

01-800-00-214-00 in the Mexican Republic;
For calls originating in Mexico City and the Metropolitan Area: 5559-1588;
For calls originating elsewhere, call: 011-52-555-559-1588.

CENACOM:

01-800-00-413-00 in the Mexican Republic;
For calls originating in Mexico City and the Metropolitan Area: 5550-1496, 5550-1552, 5550-1485, or 5550-4885;
For calls originating elsewhere, call: 011-52-555-550-1496, or 011-52-555-550-1552; 011-52-555-550-1485, or 011-52-555-550-4885.

ARGENTINA:

CIQUIME:

0-800-222-2933 in the Republic of Argentina;
For calls originating elsewhere, call: +54-11-4613-1100.

BRAZIL:

PRÓ-QUÍMICA:

0-800-118270 (Toll-free in Brazil);
For calls originating elsewhere, call: +55-11-232-1144 (Collect calls are accepted).

COLUMBIA:

CISPROQUIM:

01-800-091-6012 in Colombia;
For calls originating in Bogotá, Colombia, call: 288-6012;
For calls originating elsewhere, call: 011-57-1-288-6012.

CANADA:

CANUTEC:

613-996-6666 (Collect calls are accepted);
*666 cellular (in Canada only).

UNITED STATES:

CHEMTREC®:

1-800-424-9300 (Toll-free in the U.S., Canada, and the U.S. Virgin Islands);
703-527-3887 for calls originating elsewhere (Collect calls are accepted).

CHEM-TEL, INC.:

1-800-255-3924 (Toll-free in the U.S., Canada, and the U.S. Virgin Islands);
813-248-0585 for calls originating elsewhere (Collect calls are accepted).

INFOTRAC:

1-800-535-5053 (Toll-free in the U.S., Canada, and the U.S. Virgin Islands);
352-323-3500 for calls originating elsewhere (Collect calls are accepted).

3E COMPANY:

1-800-451-8346 (Toll-free in the U.S., Canada, and the U.S. Virgin Islands);
760-602-8703 for calls originating elsewhere (Collect calls are accepted).

NATIONAL RESPONSE CENTER (NRC):

1-800-424-8802 - (24 hours) (Toll-free in the U.S., Canada, and the U.S. Virgin Islands);
202-267-2675 for calls in the District of Columbia.

MILITARY SHIPMENTS:

703-697-0218 - Explosives/ammunition incidents (Collect calls are accepted);
1-800-851-8061 - All other dangerous goods incidents.

NATIONWIDE POISON CONTROL CENTER (United States only):

1-800-222-1222 (Toll-free in the U.S.).

For additional details see the section entitled "WHO TO CALL FOR ASSISTANCE" under the ERG Instructions.
As an immediate precautionary measure, isolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids.
Keep unauthorized personnel away.
Stay upwind.
Keep out of low areas.
Ventilate enclosed areas.

AIHA ERPG Values for CAS675-14-9 (AIHA, 2006):

Not Listed

DOE TEEL Values for CAS675-14-9 (U.S. Department of Energy, Office of Emergency Management, 2010):

Listed as Cyanuric fluoride (2,4,6-Trifluoro-s-triazine)
TEEL-0 (units = mg/m3): 0.17
TEEL-1 (units = mg/m3): 0.17
TEEL-2 (units = mg/m3): 0.17
TEEL-3 (units = mg/m3): 43.3
Definitions:

TEEL-0: The threshold concentration below which most people will experience no adverse health effects.
TEEL-1: The airborne concentration (expressed as ppm [parts per million] or mg/m(3) [milligrams per cubic meter]) of a substance above which it is predicted that the general population, including susceptible individuals, could experience notable discomfort, irritation, or certain asymptomatic, nonsensory effects. However, these effects are not disabling and are transient and reversible upon cessation of exposure.
TEEL-2: The airborne concentration (expressed as ppm or mg/m(3)) of a substance above which it is predicted that the general population, including susceptible individuals, could experience irreversible or other serious, long-lasting, adverse health effects or an impaired ability to escape.
TEEL-3: The airborne concentration (expressed as ppm or mg/m(3)) of a substance above which it is predicted that the general population, including susceptible individuals, could experience life-threatening adverse health effects or death.

AEGL Values for CAS675-14-9 (National Research Council, 2010; National Research Council, 2009; National Research Council, 2008; National Research Council, 2007; NRC, 2001; NRC, 2002; NRC, 2003; NRC, 2004; NRC, 2004; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2006; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2007; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2005; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2005; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2007; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2006; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2006; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2006; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2006; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2006; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2006; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2006; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2006; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2006; United States Environmental Protection Agency Office of Pollution Prevention and Toxics, 2006; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2006; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2007; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2007; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2007; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2007; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2007; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2009; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2009; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2009; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2009; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2009; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2009; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2009; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2009; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2009; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2009; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2009; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2009; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2009; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2007; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2006; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2006; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2006; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2007; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2007; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2007; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2007; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2007; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2005; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2005; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2005; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2005; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2005; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2005; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2005; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2005; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2007; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2005; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2006; 62 FR 58840, 1997; 65 FR 14186, 2000; 65 FR 39264, 2000; 65 FR 77866, 2000; 66 FR 21940, 2001; 67 FR 7164, 2002; 68 FR 42710, 2003; 69 FR 54144, 2004):

Not Listed

NIOSH IDLH Values for CAS675-14-9 (National Institute for Occupational Safety and Health, 2007):

Not Listed

CONTAINMENT/WASTE TREATMENT OPTIONS

SUMMARY

SPILL OR LEAK PRECAUTIONS - EMERGENCY RESPONSE GUIDEBOOK, GUIDE 153 (ERG, 2004)
- ELIMINATE all ignition sources (no smoking, flares, sparks or flames in immediate area).
- Do not touch damaged containers or spilled material unless wearing appropriate protective clothing.
- Stop leak if you can do it without risk.
- Prevent entry into waterways, sewers, basements or confined areas.
- Absorb or cover with dry earth, sand or other non-combustible material and transfer to containers.
- DO NOT GET WATER INSIDE CONTAINERS.
RECOMMENDED PROTECTIVE CLOTHING - EMERGENCY RESPONSE GUIDEBOOK, GUIDE 153 (ERG, 2004)
- Wear positive pressure self-contained breathing apparatus (SCBA).
- Wear chemical protective clothing that is specifically recommended by the manufacturer. It may provide little or no thermal protection.
- Structural firefighters' protective clothing provides limited protection. fire situations ONLY; it is not effective in spill situations where direct contact with the substance is possible.
Avoid inhalation and skin contact. Wear respiratory protection and full protective clothing (EPA, 1985).
For the similar compound, cyanuric chloride, contain spill with earth, sand, or absorbent material which does not react with spilled material. For small spills, shovel into clean, dry, labelled containers and cover. For large spills, contact fire and emergency services and supplier for advice (CHEMINFO , 1990).

SMALL LEAK/SPILL

Avoid inhalation of and skin contact with cyanuric fluoride. Wear respiratory protection and full protective clothing when material has been spilled or released (EPA, 1985).
For the similar compound, cyanuric chloride: Do not touch spilled material. Prevent material from entering sewers or confined spaces. Stop or reduce leak if safe to do so. Shovel spill material into clean, dry, labelled container and cover. Flush area with water. Do not get water inside containers or on spilled material (CHEMINFO , 1990).

LARGE LEAK/SPILL

Avoid inhalation of and skin contact with cyanuric fluoride. Wear respiratory protection and full protective clothing when material has been spilled or released (EPA, 1985).
For the similar compound, cyanuric chloride: Do not touch spilled material. Prevent material from entering sewers or confined spaces. Stop or reduce leak if safe to do so. Contact fire and emergency services and supplier for advice (CHEMINFO , 1990).

-ENVIRONMENTAL HAZARD MANAGEMENT

POLLUTION HAZARD

There was no information on pollution hazards for cyanuric fluoride in available references at the time of this review.

ENVIRONMENTAL FATE AND KINETICS

OTHER

OTHER
- There was no information on environmental kinetics for cyanuric fluoride in available references at the time of this review.

ENVIRONMENTAL TOXICITY

There was no information on environmental toxicity for cyanuric fluoride in available references at the time of this review.

-PHYSICAL/CHEMICAL PROPERTIES

MOLECULAR WEIGHT

135.06 (Lewis, 1996)

DESCRIPTION/PHYSICAL STATE

Liquid (EPA, 2003)

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National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances: Acute Exposure Guideline Levels (AEGLs) for Ethyl Isocyanate (Proposed). United States Environmental Protection Agency. Washington, DC. 2008h. Available from URL: http://www.regulations.gov/search/Regs/contentStreamer?objectId=090000648091884e&disposition=attachment&contentType=pdf. As accessed 2010-08-15.

National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances: Acute Exposure Guideline Levels (AEGLs) for Ethyl Phosphorodichloridate (Proposed). United States Environmental Protection Agency. Washington, DC. 2008i. Available from URL: http://www.regulations.gov/search/Regs/contentStreamer?objectId=0900006480920347&disposition=attachment&contentType=pdf. As accessed 2010-08-15.

National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances: Acute Exposure Guideline Levels (AEGLs) for Ethylbenzene (Proposed). United States Environmental Protection Agency. Washington, DC. 2008g. Available from URL: http://www.regulations.gov/search/Regs/contentStreamer?objectId=09000064809203e7&disposition=attachment&contentType=pdf. As accessed 2010-08-15.

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National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances: Acute Exposure Guideline Levels (AEGLs) for Germane (Proposed). United States Environmental Protection Agency. Washington, DC. 2008j. Available from URL: http://www.regulations.gov/search/Regs/contentStreamer?objectId=0900006480963906&disposition=attachment&contentType=pdf. As accessed 2010-08-15.

National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances: Acute Exposure Guideline Levels (AEGLs) for Hexafluoropropylene (Proposed). United States Environmental Protection Agency. Washington, DC. 2006. Available from URL: http://www.regulations.gov/search/Regs/contentStreamer?objectId=09000064801ea1f5&disposition=attachment&contentType=pdf. As accessed 2010-08-15.

National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances: Acute Exposure Guideline Levels (AEGLs) for Ketene (Proposed). United States Environmental Protection Agency. Washington, DC. 2007. Available from URL: http://www.regulations.gov/search/Regs/contentStreamer?objectId=090000648020ee7c&disposition=attachment&contentType=pdf. As accessed 2010-08-15.

National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances: Acute Exposure Guideline Levels (AEGLs) for Magnesium Aluminum Phosphide (Proposed). United States Environmental Protection Agency. Washington, DC. 2005h. Available from URL: http://www.regulations.gov/search/Regs/contentStreamer?objectId=090000648020c5ed&disposition=attachment&contentType=pdf. As accessed 2010-08-16.

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National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances: Acute Exposure Guideline Levels (AEGLs) for Malathion (Proposed). United States Environmental Protection Agency. Washington, DC. 2009k. Available from URL: http://www.regulations.gov/search/Regs/contentStreamer?objectId=09000064809639df&disposition=attachment&contentType=pdf. As accessed 2010-08-15.

National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances: Acute Exposure Guideline Levels (AEGLs) for Mercury Vapor (Proposed). United States Environmental Protection Agency. Washington, DC. 2009b. Available from URL: http://www.regulations.gov/search/Regs/contentStreamer?objectId=0900006480a8a087&disposition=attachment&contentType=pdf. As accessed 2010-08-12.

National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances: Acute Exposure Guideline Levels (AEGLs) for Methyl Isothiocyanate (Proposed). United States Environmental Protection Agency. Washington, DC. 2008k. Available from URL: http://www.regulations.gov/search/Regs/contentStreamer?objectId=0900006480963a03&disposition=attachment&contentType=pdf. As accessed 2010-08-15.

National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances: Acute Exposure Guideline Levels (AEGLs) for Methyl Parathion (Proposed). United States Environmental Protection Agency. Washington, DC. 2008l. Available from URL: http://www.regulations.gov/search/Regs/contentStreamer?objectId=0900006480963a57&disposition=attachment&contentType=pdf. As accessed 2010-08-12.

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National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances: Acute Exposure Guideline Levels (AEGLs) for Nitrogen Trifluoride (Proposed). United States Environmental Protection Agency. Washington, DC. 2009l. Available from URL: http://www.regulations.gov/search/Regs/contentStreamer?objectId=0900006480963e0c&disposition=attachment&contentType=pdf. As accessed 2010-08-12.

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National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances: Acute Exposure Guideline Levels (AEGLs) for Perchloryl Fluoride (Proposed). United States Environmental Protection Agency. Washington, DC. 2009c. Available from URL: http://www.regulations.gov/search/Regs/contentStreamer?objectId=0900006480a7e268&disposition=attachment&contentType=pdf. As accessed 2010-08-12.

National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances: Acute Exposure Guideline Levels (AEGLs) for Perfluoroisobutylene (Proposed). United States Environmental Protection Agency. Washington, DC. 2009d. Available from URL: http://www.regulations.gov/search/Regs/contentStreamer?objectId=0900006480a7e26a&disposition=attachment&contentType=pdf. As accessed 2010-08-15.

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CYANURIC FLUORIDE

Classification | Information to evaluate chemical incidents

Information to evaluate chemical incidents

Information to evaluate chemical incidents

Information to evaluate chemical incidents