4-DIMETHYLAMINOAZOBENZENE
HAZARDTEXT ®
Information to help in the initial response for evaluating chemical incidents
-IDENTIFICATION
SYNONYMS
4-DIMETHYLAMINOAZOBENZENE ANILINE, N,N-DIMETHYL-p-PHENYLAZO- ATUL FAST YELLOW R AZOBENZENE, p-DIMETHYLAMINO- BENZENAMINE, N,N-DIMETHYL-4-(PHENYLAZO)- BENZENEAZODIMETHYLANILINE BRILLIANT FAST OIL YELLOW BRILLIANT FAST SPIRIT YELLOW BRILLIANT FAST YELLOW BRILLIANT OIL YELLOW BUTTER YELLOW CERASINE YELLOW GG C.I. SOLVENT YELLOW 2 DAB p-DIMETHYLAMINOAZOBENZEN (Czech) DIMETHYLAMINOAZOBENZENE N,N-DIMETHYL-p-AMINOAZOBENZENE N,N-DIMETHYL-4-AMINOAZOBENZENE p-DIMETHYLAMINOAZOBENZENE 4-(DIMETHYLAMINO)AZOBENZENE 4-(N,N-DIMETHYLAMINO)AZOBENZENE DIMETHYLAMINOAZOBENZOL p-DIMETHYLAMINO-AZOBENZOL (German) 4-DIMETHYLAMINOAZOBENZOL 4-DIMETHYLAMINOPHENYLAZOBENZENE N,N-DIMETHYL-p-AZOANILINE N,N-DIMETHYL-p-PHENYLAZOANILINE N,N-DIMETHYL-4-(PHENYLAZO)BENZAMINE N,N-DIMETHYL-4-(PHENYLAZO)BENZENAMINE DIMETHYL YELLOW DIMETHYL YELLOW ANALAR DIMETHYL YELLOW N,N-DIMETHYLANILINE DMAB ENIAL YELLOW 2G FAST OIL YELLOW B FAST YELLOW FAT YELLOW FAT YELLOW A FAT YELLOW AD OO FAT YELLOW ES FAT YELLOW ES EXTRA FAT YELLOW EXTRA CONC. FAT YELLOW R FAT YELLOW R (8186) GRASAL BRILLIANT YELLOW IKETON YELLOW EXTRA JAUNE DE BEURRE (French) METHYL YELLOW OIL YELLOW OIL YELLOW II OIL YELLOW 20 OIL YELLOW 2625 OIL YELLOW 7463 OIL YELLOW BB OIL YELLOW D OIL YELLOW DN OIL YELLOW FF OIL YELLOW FN OIL YELLOW G OIL YELLOW 2G OIL YELLOW G-2 OIL YELLOW GG OIL YELLOW GR OIL YELLOW N OIL YELLOW PEL OIL YELLOW S OLEAL YELLOW 2G ORGANOL YELLOW ADM ORIENT OIL YELLOW GG P.D.A.B. PETROL YELLOW WT 4-(PHENYLAZO)-N,N-DIMETHYLANILINE RESINOL YELLOW GR RESOFORM YELLOW GGA SILOTRAS YELLOW T2G SOMALIA YELLOW A STEAR YELLOW JB SUDAN GG SUDAN YELLOW SUDAN YELLOW GG SUDAN YELLOW GGA TOYO OIL YELLOW G WAXOLINE YELLOW AD WAXOLINE YELLOW ADS YELLOW G SOLUBLE IN GREASE ZLUT MASELNA (Czech) ZLUT ROZPOUSTEDLOVA 2 (Czech) BRILLIANT OIL YELLOW (BENZENAZODIMETHYLANILINE) DAB (CARCINOGEN) ZLUT ROZPOUSTEDLOVA (CZECH)
IDENTIFIERS
Editor's Note: This material is not listed in the Emergency Response Guidebook. Based on the material's physical and chemical properties, toxicity, or chemical group, a guide has been assigned. For additional technical information, contact one of the emergency response telephone numbers listed under Public Safety Measures.
SYNONYM REFERENCE
- (NIOSH, 1995;(RTECS , 1995)
USES/FORMS/SOURCES
4-Dimethylaminoazobenzene has been utilized as a chemical indicator (pH indicator), in dyes for polishes/waxes and other products, and in organic research (Clayton & Clayton, 1994; (Hathaway et al, 1991; Lewis, 1993). Currently, this compound is used in laboratory work as a model of tumorigenic activity in animals (Hathaway et al, 1991). At this time, 4-dimethylaminoazobenzene is not commercially produced or used in the US (HSDB , 1995).
4-Dimethylaminoazobenzene is a yellow, leaf-shaped crystalline solid (Clayton & Clayton, 1994; (Lewis, 1992) NIOSH, 1995).
-CLINICAL EFFECTS
GENERAL CLINICAL EFFECTS
- 4-Dimethylaminoazobenzene may be toxic by inhalation, ingestion, and skin or eye exposure. It is a potential occupational carcinogen.
- Symptoms of exposure include contact dermatitis; enlarged liver; kidney and liver dysfunction; cough, wheezing, and dyspnea; bloody sputum; bronchial secretions; and frequent urination, hematuria, and dysuria.
- POTENTIAL HEALTH HAZARDS - EMERGENCY RESPONSE GUIDEBOOK, GUIDE 153 (ERG, 2004)
TOXIC; inhalation, ingestion or skin contact with material may cause severe injury or death. Contact with molten substance may cause severe burns to skin and eyes. Avoid any skin contact. Effects of contact or inhalation may be delayed. Fire may produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution.
-MEDICAL TREATMENT
LIFE SUPPORT
- Support respiratory and cardiovascular function.
SUMMARY
- FIRST AID - EMERGENCY RESPONSE GUIDEBOOK, GUIDE 153 (ERG, 2004)
Move victim to fresh air. Call 911 or emergency medical service. Give artificial respiration if victim is not breathing. Do not use mouth-to-mouth method if victim ingested or inhaled the substance; give artificial respiration with the aid of a pocket mask equipped with a one-way valve or other proper respiratory medical device. Administer oxygen if breathing is difficult. Remove and isolate contaminated clothing and shoes. In case of contact with substance, immediately flush skin or eyes with running water for at least 20 minutes. For minor skin contact, avoid spreading material on unaffected skin. Keep victim warm and quiet. Effects of exposure (inhalation, ingestion or skin contact) to substance may be delayed. Ensure that medical personnel are aware of the material(s) involved and take precautions to protect themselves.
FIRST AID GENERAL Move victims of inhalation exposure from the toxic environment and administer 100% humidified supplemental oxygen with assisted ventilation as required. Exposed skin and eyes should be copiously flushed with water. Following ingestion, measures to decrease absorption may be useful if the patient is seen soon after the exposure.
INHALATION EXPOSURE INHALATION: Move patient to fresh air. Monitor for respiratory distress. If cough or difficulty breathing develops, evaluate for respiratory tract irritation, bronchitis, or pneumonitis. Administer oxygen and assist ventilation as required. Treat bronchospasm with an inhaled beta2-adrenergic agonist. Consider systemic corticosteroids in patients with significant bronchospasm. If bronchospasm and wheezing occur, consider treatment with inhaled sympathomimetic agents.
DERMAL EXPOSURE DECONTAMINATION: Remove contaminated clothing and jewelry and place them in plastic bags. Wash exposed areas with soap and water for 10 to 15 minutes with gentle sponging to avoid skin breakdown. A physician may need to examine the area if irritation or pain persists (Burgess et al, 1999). Treat dermal irritation or burns with standard topical therapy. Patients developing dermal hypersensitivity reactions may require treatment with systemic or topical corticosteroids or antihistamines.
EYE EXPOSURE DECONTAMINATION: Remove contact lenses and irrigate exposed eyes with copious amounts of room temperature 0.9% saline or water for at least 15 minutes. If irritation, pain, swelling, lacrimation, or photophobia persist after 15 minutes of irrigation, the patient should be seen in a healthcare facility.
INGESTION EXPOSURE Measures to decrease absorption may be useful. The decision to induce or not to induce emesis in ingestions must be carefully considered. If the patient has any signs of esophageal or gastrointestinal tract irritation or burns, or has evidence of a decreased sensorium, a depressed gag reflex, or impending shock, INDUCED EMESIS SHOULD BE AVOIDED. GASTRIC LAVAGE: Consider after ingestion of a potentially life-threatening amount of poison if it can be performed soon after ingestion (generally within 1 hour). Protect airway by placement in the head down left lateral decubitus position or by endotracheal intubation. Control any seizures first. ACTIVATED CHARCOAL: Administer charcoal as a slurry (240 mL water/30 g charcoal). Usual dose: 25 to 100 g in adults/adolescents, 25 to 50 g in children (1 to 12 years), and 1 g/kg in infants less than 1 year old. Carefully observe patients with ingestion exposure for the development of any systemic signs or symptoms and administer symptomatic treatment as necessary.
-RANGE OF TOXICITY
MINIMUM LETHAL EXPOSURE
MAXIMUM TOLERATED EXPOSURE
The maximum tolerated human exposure to this agent has not been delineated. Based on animal data, this compound is thought to be a probable carcinogen in humans, although there are no reports of an increased cancer incidence among exposed populations (Budavari, 1989; Hathaway et al, 1991; HSDB , 1995). Contact dermatitis was seen in 90% of workers handling this substance (Hathaway et al, 1991).
The following are only a few of the studies which indicate that 4-dimethylaminoazobenzene is a potent carcinogen in animals. In rats, oral administration of between 1 and 30 mg/day produced liver tumors. The larger the dose, the more quickly tumors became manifest (Hathaway et al, 1991). Application of 1 mL of a 2% 4-dimethylaminoazobenzene solution, two times a week for 90 weeks, caused skin tumors in all rats so treated. Anaplastic, basal cell, and squamous cell carcinomas were observed (Hathaway et al, 1991).
- Carcinogenicity Ratings for CAS60-11-7 :
ACGIH (American Conference of Governmental Industrial Hygienists, 2010): Not Listed EPA (U.S. Environmental Protection Agency, 2011): Not Listed IARC (International Agency for Research on Cancer (IARC), 2016; International Agency for Research on Cancer, 2015; IARC Working Group on the Evaluation of Carcinogenic Risks to Humans, 2010; IARC Working Group on the Evaluation of Carcinogenic Risks to Humans, 2010a; IARC Working Group on the Evaluation of Carcinogenic Risks to Humans, 2008; IARC Working Group on the Evaluation of Carcinogenic Risks to Humans, 2007; IARC Working Group on the Evaluation of Carcinogenic Risks to Humans, 2006; IARC, 2004): 2B ; Listed as: para-Dimethylaminoazobenzene 2B : The agent (mixture) is possibly carcinogenic to humans. The exposure circumstance entails exposures that are possibly carcinogenic to humans. This category is used for agents, mixtures and exposure circumstances for which there is limited evidence of carcinogenicity in humans and less than sufficient evidence of carcinogenicity in experimental animals. It may also be used when there is inadequate evidence of carcinogenicity in humans but there is sufficient evidence of carcinogenicity in experimental animals. In some instances, an agent, mixture or exposure circumstance for which there is inadequate evidence of carcinogenicity in humans but limited evidence of carcinogenicity in experimental animals together with supporting evidence from other relevant data may be placed in this group.
NIOSH (National Institute for Occupational Safety and Health, 2007): Ca ; Listed as: 4-Dimethylaminoazobenzene MAK (DFG, 2002): Not Listed NTP (U.S. Department of Health and Human Services, Public Health Service, National Toxicology Project ): Not Listed
TOXICITY AND RISK ASSESSMENT VALUES
- EPA Risk Assessment Values for CAS60-11-7 (U.S. Environmental Protection Agency, 2011):
-STANDARDS AND LABELS
WORKPLACE STANDARDS
- ACGIH TLV Values for CAS60-11-7 (American Conference of Governmental Industrial Hygienists, 2010):
- AIHA WEEL Values for CAS60-11-7 (AIHA, 2006):
- NIOSH REL and IDLH Values for CAS60-11-7 (National Institute for Occupational Safety and Health, 2007):
- OSHA PEL Values for CAS60-11-7 (U.S. Occupational Safety, and Health Administration (OSHA), 2010):
- OSHA List of Highly Hazardous Chemicals, Toxics, and Reactives for CAS60-11-7 (U.S. Occupational Safety and Health Administration, 2010):
ENVIRONMENTAL STANDARDS
- EPA CERCLA, Hazardous Substances and Reportable Quantities for CAS60-11-7 (U.S. Environmental Protection Agency, 2010):
Listed as: Benzenamine, N,N-dimethyl-4-(phenylazo)- Final Reportable Quantity, in pounds (kilograms): Additional Information: Listed as: Dimethyl aminoazobenzene Final Reportable Quantity, in pounds (kilograms): Additional Information: Listed as: p-Dimethylaminoazobenzene Final Reportable Quantity, in pounds (kilograms): Additional Information:
- EPA CERCLA, Hazardous Substances and Reportable Quantities, Radionuclides for CAS60-11-7 (U.S. Environmental Protection Agency, 2010):
- EPA RCRA Hazardous Waste Number for CAS60-11-7 (U.S. Environmental Protection Agency, 2010b):
Listed as: Benzenamine, N,N-dimethyl-4-(phenylazo)- P or U series number: U093 Footnote: Listed as: p-Dimethylaminoazobenzene P or U series number: U093 Footnote: Editor's Note: The D, F, and K series waste numbers and Appendix VIII to Part 261 -- Hazardous Constituents were not included. Please refer to 40 CFR Part 261.
- EPA SARA Title III, Extremely Hazardous Substance List for CAS60-11-7 (U.S. Environmental Protection Agency, 2010):
- EPA SARA Title III, Community Right-to-Know for CAS60-11-7 (40 CFR 372.65, 2006; 40 CFR 372.28, 2006):
Listed as: 4-Dimethylaminoazobenzene Effective Date for Reporting Under 40 CFR 372.30: 1/1/87 Lower Thresholds for Chemicals of Special Concern under 40 CFR 372.28:
- DOT List of Marine Pollutants for CAS60-11-7 (49 CFR 172.101 - App. B, 2005):
- EPA TSCA Inventory for CAS60-11-7 (EPA, 2005):
SHIPPING REGULATIONS
- DOT -- Table of Hazardous Materials and Special Provisions (49 CFR 172.101, 2005):
- ICAO International Shipping Name (ICAO, 2002):
LABELS
- NFPA Hazard Ratings for CAS60-11-7 (NFPA, 2002):
-HANDLING AND STORAGE
HANDLING
- Precautions for carcinogens must be observed when handling this compound (HSDB , 1995).
- From 49 CFR 171-177: "No person may /transport,/ offer or accept a hazardous material for transportation in commerce unless that material is properly classed, described, packaged, marked, labeled, and in condition for shipment as required or authorized by the hazardous materials regulations" (HSDB , 1995)
-PERSONAL PROTECTION
SUMMARY
- RECOMMENDED PROTECTIVE CLOTHING - EMERGENCY RESPONSE GUIDEBOOK, GUIDE 153 (ERG, 2004)
Wear positive pressure self-contained breathing apparatus (SCBA). Wear chemical protective clothing that is specifically recommended by the manufacturer. It may provide little or no thermal protection. Structural firefighters' protective clothing provides limited protection. fire situations ONLY; it is not effective in spill situations where direct contact with the substance is possible.
- Appropriate protective clothing should be worn to prevent skin contact. If skin contact occurs, washing should be done immediately. In addition, persons working with this compound should wash thoroughly at the end of each work shift and change into uncontaminated clothing before leaving the job site. Contaminated clothing should be removed and replaced (NIOSH, 1995).
- All precautions for dealing with carcinogens should be observed (HSDB , 1995).
EYE/FACE PROTECTION
- Use appropriate eye protection to prevent contact with this substance. In areas where there is any possibility that persons may be exposed to 4-dimethylaminoazobenzene, eyewash fountains should be provided (NIOSH, 1995).
RESPIRATORY PROTECTION
- Refer to "Recommendations for respirator selection" in the NIOSH Pocket Guide to Chemical Hazards on TOMES Plus(R) for respirator information.
PROTECTIVE CLOTHING
- CHEMICAL PROTECTIVE CLOTHING. Search results for CAS 60-11-7.
ENGINEERING CONTROLS
- A facility for quickly drenching the body, or body parts, with water needs to be provided within the immediate work area. This is intended to quickly remove 4-dimethylaminoazobenzene from any body areas likely to be exposed. In some instances a hose connected to a sink may be permissible; in others a full deluge shower may be required (NIOSH, 1995).
-PHYSICAL HAZARDS
FIRE HAZARD
Editor's Note: This material is not listed in the Emergency Response Guidebook. Based on the material's physical and chemical properties, toxicity, or chemical group, a guide has been assigned. For additional technical information, contact one of the emergency response telephone numbers listed under Public Safety Measures. POTENTIAL FIRE OR EXPLOSION HAZARDS - EMERGENCY RESPONSE GUIDEBOOK, GUIDE 153 (ERG, 2004) Combustible material: may burn but does not ignite readily. When heated, vapors may form explosive mixtures with air: indoors, outdoors and sewers explosion hazards. Those substances designated with a "P" may polymerize explosively when heated or involved in a fire. Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated. Runoff may pollute waterways. Substance may be transported in a molten form.
4-Dimethylaminoazobenzene emits poisonous fumes of nitrogen oxides when heated to decomposition (Lewis, 1992).
- FLAMMABILITY CLASSIFICATION
- NFPA Flammability Rating for CAS60-11-7 (NFPA, 2002):
- FIRE CONTROL/EXTINGUISHING AGENTS
- SMALL FIRE PRECAUTIONS - EMERGENCY RESPONSE GUIDEBOOK, GUIDE 153 (ERG, 2004)
- LARGE FIRE PRECAUTIONS - EMERGENCY RESPONSE GUIDEBOOK, GUIDE 153 (ERG, 2004)
Dry chemical, CO2, alcohol-resistant foam or water spray. Move containers from fire area if you can do it without risk. Dike fire control water for later disposal; do not scatter the material.
- TANK OR CAR/TRAILER LOAD FIRE PRECAUTIONS - EMERGENCY RESPONSE GUIDEBOOK, GUIDE 153 (ERG, 2004)
Fight fire from maximum distance or use unmanned hose holders or monitor nozzles. Do not get water inside containers. Cool containers with flooding quantities of water until well after fire is out. Withdraw immediately in case of rising sound from venting safety devices or discoloration of tank. ALWAYS stay away from tanks engulfed in fire.
- NFPA Extinguishing Methods for CAS60-11-7 (NFPA, 2002):
REACTIVITY HAZARD
- 4-Dimethylaminoazobenzene emits poisonous fumes of nitrogen oxides when heated to decomposition (Lewis, 1992).
EVACUATION PROCEDURES
- Editor's Note: This material is not listed in the Table of Initial Isolation and Protective Action Distances.
- SPILL - PUBLIC SAFETY EVACUATION DISTANCES - EMERGENCY RESPONSE GUIDEBOOK, GUIDE 153 (ERG, 2004)
Increase, in the downwind direction, as necessary, the isolation distance of at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids in all directions.
- FIRE - PUBLIC SAFETY EVACUATION DISTANCES - EMERGENCY RESPONSE GUIDEBOOK, GUIDE 153 (ERG, 2004)
If tank, rail car or tank truck is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions.
- PUBLIC SAFETY MEASURES - EMERGENCY RESPONSE GUIDEBOOK, GUIDE 153 (ERG, 2004)
CALL Emergency Response Telephone Number on Shipping Paper first. If Shipping Paper not available or no answer, refer to appropriate telephone number: MEXICO: SETIQ: 01-800-00-214-00 in the Mexican Republic; For calls originating in Mexico City and the Metropolitan Area: 5559-1588; For calls originating elsewhere, call: 011-52-555-559-1588.
CENACOM: 01-800-00-413-00 in the Mexican Republic; For calls originating in Mexico City and the Metropolitan Area: 5550-1496, 5550-1552, 5550-1485, or 5550-4885; For calls originating elsewhere, call: 011-52-555-550-1496, or 011-52-555-550-1552; 011-52-555-550-1485, or 011-52-555-550-4885.
ARGENTINA: CIQUIME: 0-800-222-2933 in the Republic of Argentina; For calls originating elsewhere, call: +54-11-4613-1100.
BRAZIL: PRÓ-QUÍMICA: 0-800-118270 (Toll-free in Brazil); For calls originating elsewhere, call: +55-11-232-1144 (Collect calls are accepted).
COLUMBIA: CISPROQUIM: 01-800-091-6012 in Colombia; For calls originating in Bogotá, Colombia, call: 288-6012; For calls originating elsewhere, call: 011-57-1-288-6012.
CANADA: UNITED STATES:
For additional details see the section entitled "WHO TO CALL FOR ASSISTANCE" under the ERG Instructions. As an immediate precautionary measure, isolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids. Keep unauthorized personnel away. Stay upwind. Keep out of low areas. Ventilate enclosed areas.
- AIHA ERPG Values for CAS60-11-7 (AIHA, 2006):
- DOE TEEL Values for CAS60-11-7 (U.S. Department of Energy, Office of Emergency Management, 2010):
Listed as Dimethylaminoazobenzene, 4- TEEL-0 (units = mg/m3): 4 TEEL-1 (units = mg/m3): 12.5 TEEL-2 (units = mg/m3): 75 TEEL-3 (units = mg/m3): 75 Definitions: TEEL-0: The threshold concentration below which most people will experience no adverse health effects. TEEL-1: The airborne concentration (expressed as ppm [parts per million] or mg/m(3) [milligrams per cubic meter]) of a substance above which it is predicted that the general population, including susceptible individuals, could experience notable discomfort, irritation, or certain asymptomatic, nonsensory effects. However, these effects are not disabling and are transient and reversible upon cessation of exposure. TEEL-2: The airborne concentration (expressed as ppm or mg/m(3)) of a substance above which it is predicted that the general population, including susceptible individuals, could experience irreversible or other serious, long-lasting, adverse health effects or an impaired ability to escape. TEEL-3: The airborne concentration (expressed as ppm or mg/m(3)) of a substance above which it is predicted that the general population, including susceptible individuals, could experience life-threatening adverse health effects or death.
- AEGL Values for CAS60-11-7 (National Research Council, 2010; National Research Council, 2009; National Research Council, 2008; National Research Council, 2007; NRC, 2001; NRC, 2002; NRC, 2003; NRC, 2004; NRC, 2004; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2006; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2007; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2005; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2005; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2007; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2006; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2006; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2006; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2006; 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National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2009; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2009; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2009; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2009; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2009; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2009; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2009; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2008; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2007; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2006; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2006; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2006; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2007; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2007; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2007; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2007; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2007; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2005; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2005; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2005; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2005; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2005; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2005; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2005; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2005; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2007; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2005; National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances, 2006; 62 FR 58840, 1997; 65 FR 14186, 2000; 65 FR 39264, 2000; 65 FR 77866, 2000; 66 FR 21940, 2001; 67 FR 7164, 2002; 68 FR 42710, 2003; 69 FR 54144, 2004):
- NIOSH IDLH Values for CAS60-11-7 (National Institute for Occupational Safety and Health, 2007):
CONTAINMENT/WASTE TREATMENT OPTIONS
SPILL OR LEAK PRECAUTIONS - EMERGENCY RESPONSE GUIDEBOOK, GUIDE 153 (ERG, 2004) ELIMINATE all ignition sources (no smoking, flares, sparks or flames in immediate area). Do not touch damaged containers or spilled material unless wearing appropriate protective clothing. Stop leak if you can do it without risk. Prevent entry into waterways, sewers, basements or confined areas. Absorb or cover with dry earth, sand or other non-combustible material and transfer to containers. DO NOT GET WATER INSIDE CONTAINERS.
RECOMMENDED PROTECTIVE CLOTHING - EMERGENCY RESPONSE GUIDEBOOK, GUIDE 153 (ERG, 2004) Wear positive pressure self-contained breathing apparatus (SCBA). Wear chemical protective clothing that is specifically recommended by the manufacturer. It may provide little or no thermal protection. Structural firefighters' protective clothing provides limited protection. fire situations ONLY; it is not effective in spill situations where direct contact with the substance is possible.
4-Dimethylaminoazobenzene may be a candidate for the following: Fluidized bed incineration at a temperature range of 450 to 980 degrees C (residence time of seconds for liquids and gases, longer for solids); rotary kiln incineration at a temperature range of 820 to 1600 degrees C (residence time of seconds for liquids and gases and hours for solids) (HSDB , 1995). Waste management activities associated with material disposition are unique to individual situations. Proper waste characterization and decisions regarding waste management should be coordinated with the appropriate local, state, or federal authorities to ensure compliance with all applicable rules and regulations.
-ENVIRONMENTAL HAZARD MANAGEMENT
POLLUTION HAZARD
- 4-Dimethylaminoazobenzene's release to the environment probably occurred via its production and use. This compound is not known to occur naturally (HSDB , 1995).
ENVIRONMENTAL FATE AND KINETICS
In the atmosphere, this compound may exist primarily adsorbed onto particulates. Vapor may be subject to direct photolysis. Reaction with photochemically produced hydroxyl radicals may be an important route; a vapor-phase half-life of 7.04 hours is estimated (HSDB , 1995).
SURFACE WATER 4-Dimethylaminoazobenzene may undergo direct photolysis, adsorb to sediment, and bioconcentrate in aquatic organisms. It is not predicted to evaporate or hydrolyze. It may biodegrade (HSDB , 1995).
BIODEGRADATION
- There is some evidence that 4-dimethylaminoazobenzene is biodegraded. This compound (at a level of 0.29 ppm) was incubated with a culture of settled domestic wastewater; after 7 days it appeared at only trace levels. It was not detected at all in 1st, 2nd, and 3rd subcultures (HSDB , 1995).
BIOACCUMULATION
ENVIRONMENTAL TOXICITY
- No information found at the time of this review.
-PHYSICAL/CHEMICAL PROPERTIES
MOLECULAR WEIGHT
DESCRIPTION/PHYSICAL STATE
- 4-Dimethylaminoazobenzene is a yellow, leaf-shaped crystalline solid (Clayton & Clayton, 1994; (Lewis, 1992) NIOSH, 1995).
VAPOR PRESSURE
- 3.0x10(-7) mmHg (estimated) (NIOSH, 1995)
FREEZING/MELTING POINT
116 degrees C; 237 degrees F (Lewis, 1993) NIOSH, 1995) 114-117 degrees C (Budavari, 1989) Clayton & Clayton, 1994)
BOILING POINT
SOLUBILITY
This compound is 0.001% (by weight) soluble in water; essentially insoluble in water (Budavari, 1989) Clayton & Clayton, 1994; (Lewis, 1992) NIOSH, 1995). water solubility: 13.6 ppm (HSDB , 1995)
It is soluble in alcohol, benzene, chloroform, ether, strong mineral acids, oils, and petroleum ether (Budavari, 1989) Clayton & Clayton, 1994; (Lewis, 1993).
OCTANOL/WATER PARTITION COEFFICIENT
- log Kow = 4.58 (HSDB , 1995)
HENRY'S CONSTANT
- 7.1x10(-9) atm m(3)/mol (calculated) (HSDB , 1995)
SPECTRAL CONSTANTS
OTHER/PHYSICAL
- NUCLEAR MAGNETIC RESONANCE
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